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E8Y987

- E8Y987_ECOKO

UniProt

E8Y987 - E8Y987_ECOKO

Protein

Glutaminase

Gene

yneH

Organism
Escherichia coli (strain ATCC 55124 / KO11)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei66 – 661SubstrateUniRule annotation
    Binding sitei117 – 1171SubstrateUniRule annotation
    Binding sitei161 – 1611SubstrateUniRule annotation
    Binding sitei168 – 1681SubstrateUniRule annotation
    Binding sitei192 – 1921SubstrateUniRule annotation
    Binding sitei244 – 2441SubstrateUniRule annotation
    Binding sitei262 – 2621Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    HydrolaseUniRule annotationSAAS annotationImported

    Enzyme and pathway databases

    BioCyciECOL595495:GI1Q-2336-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:yneHImported
    Synonyms:glsAUniRule annotation
    Ordered Locus Names:EKO11_2292Imported
    ORF Names:KO11_15545Imported
    OrganismiEscherichia coli (strain ATCC 55124 / KO11)Imported
    Taxonomic identifieri595495 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000002250: Chromosome, UP000010089: Chromosome

    PTM / Processingi

    Keywords - PTMi

    AcetylationUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Structurei

    3D structure databases

    SMRiE8Y987. Positions 24-308.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    KOiK01425.
    OMAiMSIAVWS.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E8Y987-1 [UniParc]FASTAAdd to Basket

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    MAVAMDNAIL ENILRQVRPL IGQGKVADYI PALATVDGSR LGIAICTVDG    50
    QLFQAGDAQE RFSIQSISKV LSLVVAMRHY SEEEIWQRVG KDPSGSPFNS 100
    LVQLEMEQGI PRNPFINAGA LVVCDMLQGR LSAPRQRMLE VVRGLSGVSD 150
    ISYDTVVARS EFEHSARNAA IAWLMKSFGN FHHDVTTVLQ NYFHYCALKM 200
    SCVELARTFV FLANQGKAIH IDEPVVTPMQ ARQINALMAT SGMYQNAGEF 250
    AWRVGLPAKS GVGGGIVAIV PHEMAIAVWS PELDDAGNSL AGIAVLEQLT 300
    KQLGRSVY 308
    Length:308
    Mass (Da):33,516
    Last modified:April 5, 2011 - v1
    Checksum:iDDC39D9DC0D8A651
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002516 Genomic DNA. Translation: ADX50901.1.
    CP002970 Genomic DNA. Translation: AFH18078.1.
    RefSeqiYP_005277965.1. NC_016902.1.
    YP_006165430.1. NC_017660.1.

    Genome annotation databases

    EnsemblBacteriaiADX50901; ADX50901; EKO11_2292.
    AFH18078; AFH18078; KO11_15545.
    GeneIDi11777112.
    12763601.
    KEGGiekf:KO11_15545.
    eko:EKO11_2292.
    PATRICi48644556. VBIEscCol13896_2320.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002516 Genomic DNA. Translation: ADX50901.1 .
    CP002970 Genomic DNA. Translation: AFH18078.1 .
    RefSeqi YP_005277965.1. NC_016902.1.
    YP_006165430.1. NC_017660.1.

    3D structure databases

    SMRi E8Y987. Positions 24-308.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADX50901 ; ADX50901 ; EKO11_2292 .
    AFH18078 ; AFH18078 ; KO11_15545 .
    GeneIDi 11777112.
    12763601.
    KEGGi ekf:KO11_15545.
    eko:EKO11_2292.
    PATRICi 48644556. VBIEscCol13896_2320.

    Phylogenomic databases

    KOi K01425.
    OMAi MSIAVWS.

    Enzyme and pathway databases

    BioCyci ECOL595495:GI1Q-2336-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Escherichia coli KO11."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Keating D., Landick R., Woyke T.
      Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 55124 / KO11Imported and KO11Imported.
    2. "Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes."
      Turner P.C., Yomano L.P., Jarboe L.R., York S.W., Baggett C.L., Moritz B.E., Zentz E.B., Shanmugam K.T., Ingram L.O.
      J. Ind. Microbiol. Biotechnol. 39:629-639(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KO11FLImported.

    Entry informationi

    Entry nameiE8Y987_ECOKO
    AccessioniPrimary (citable) accession number: E8Y987
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3