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E8Y5E4 (E8Y5E4_ECOKO) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aldose 1-epimerase PIRNR PIRNR005096

EC=5.1.3.3 PIRNR PIRNR005096
Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096
Gene names
Name:galM EMBL AFH18966.1
Ordered Locus Names:EKO11_3130 EMBL ADX51716.1
ORF Names:KO11_20000 EMBL AFH18966.1
OrganismEscherichia coli (strain ATCC 55124 / KO11) [Complete proteome] [HAMAP] EMBL ADX51716.1
Taxonomic identifier595495 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096

Catalytic activity

Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096

Pathway

Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096

Sequence similarities

Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
   Biological processCarbohydrate metabolism PIRNR PIRNR005096
   Molecular functionIsomerase PIRNR PIRNR005096 EMBL ADX51716.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgalactose metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionaldose 1-epimerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

carbohydrate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
E8Y5E4 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 4373732BAEA83E1D

FASTA34638,190
        10         20         30         40         50         60 
MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR EALLGCASPE 

        70         80         90        100        110        120 
CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV NQLHGGPEGF DKRRWQIVNQ 

       130        140        150        160        170        180 
NDRQVLFALS SDDGDQGFPG NLGATVQYRL TDDNRISITY RATVDKPCPV NMTNHVYFNL 

       190        200        210        220        230        240 
DGEQSDVRNH KLQILADEYL PVDEGGIPHD GLKSVAGTSF DFRSAKIIAS EFLADDDQRK 

       250        260        270        280        290        300 
VKGYDHAFLL QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNFLG GTPSRGTEPY 

       310        320        330        340 
ADWQGLALES EFLPDSPNHP EWPQPDCFLR PGEEYSSLTE YQFIAE 

« Hide

References

[1]"Complete sequence of chromosome of Escherichia coli KO11."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Keating D., Landick R., Woyke T.
Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 55124 / KO11 and KO11 EMBL ADX51716.1.
[2]"Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes."
Turner P.C., Yomano L.P., Jarboe L.R., York S.W., Baggett C.L., Moritz B.E., Zentz E.B., Shanmugam K.T., Ingram L.O.
J. Ind. Microbiol. Biotechnol. 39:629-639(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KO11FL EMBL AFH18966.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002516 Genomic DNA. Translation: ADX51716.1.
CP002970 Genomic DNA. Translation: AFH18966.1.
RefSeqYP_005278780.1. NC_016902.1.
YP_006166318.1. NC_017660.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADX51716; ADX51716; EKO11_3130.
AFH18966; AFH18966; KO11_20000.
GeneID11779639.
12760331.
KEGGekf:KO11_20000.
eko:EKO11_3130.
PATRIC48646283. VBIEscCol13896_3168.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01785.

Enzyme and pathway databases

BioCycECOL595495:GI1Q-3180-MONOMER.
UniPathwayUPA00242.

Family and domain databases

Gene3D2.70.98.10. 1 hit.
InterProIPR018052. Ald1_epimerase_CS.
IPR013458. Ald_epimerase_bac.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PANTHERPTHR10091. PTHR10091. 1 hit.
PfamPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFPIRSF005096. GALM. 1 hit.
SUPFAMSSF74650. SSF74650. 1 hit.
TIGRFAMsTIGR02636. galM_Leloir. 1 hit.
PROSITEPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8Y5E4_ECOKO
AccessionPrimary (citable) accession number: E8Y5E4
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)