E8Y5E4 (E8Y5E4_ECOKO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aldose 1-epimerase PIRNR PIRNR005096
EC=5.1.3.3 PIRNR PIRNR005096

Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096

Gene names

Name:	galM EMBL AFH18966.1
Ordered Locus Names:	EKO11_3130 EMBL ADX51716.1
ORF Names:	KO11_20000 EMBL AFH18966.1

Organism

Escherichia coli (strain ATCC 55124 / KO11) [Complete proteome] [HAMAP] EMBL ADX51716.1

Taxonomic identifier

595495 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096
Catalytic activity	Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096
Pathway	Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096
Sequence similarities	Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
Biological process	Carbohydrate metabolism PIRNR PIRNR005096
Molecular function	Isomerase PIRNR PIRNR005096 EMBL ADX51716.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	galactose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	aldose 1-epimerase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E8Y5E4 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 4373732BAEA83E1D	FASTA	346	38,190
	10 20 30 40 50 60 MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR EALLGCASPE 70 80 90 100 110 120 CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV NQLHGGPEGF DKRRWQIVNQ 130 140 150 160 170 180 NDRQVLFALS SDDGDQGFPG NLGATVQYRL TDDNRISITY RATVDKPCPV NMTNHVYFNL 190 200 210 220 230 240 DGEQSDVRNH KLQILADEYL PVDEGGIPHD GLKSVAGTSF DFRSAKIIAS EFLADDDQRK 250 260 270 280 290 300 VKGYDHAFLL QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNFLG GTPSRGTEPY 310 320 330 340 ADWQGLALES EFLPDSPNHP EWPQPDCFLR PGEEYSSLTE YQFIAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequence of chromosome of Escherichia coli KO11." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Keating D., Landick R., Woyke T. Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 55124 / KO11 and KO11 EMBL ADX51716.1.
[2]	"Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes." Turner P.C., Yomano L.P., Jarboe L.R., York S.W., Baggett C.L., Moritz B.E., Zentz E.B., Shanmugam K.T., Ingram L.O. J. Ind. Microbiol. Biotechnol. 39:629-639(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: KO11FL EMBL AFH18966.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002516 Genomic DNA. Translation: ADX51716.1. CP002970 Genomic DNA. Translation: AFH18966.1.
RefSeq	YP_005278780.1. NC_016902.1. YP_006166318.1. NC_017660.1.
3D structure databases
SMR	E8Y5E4. Positions 28-343.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADX51716; ADX51716; EKO11_3130. AFH18966; AFH18966; KO11_20000.
GeneID	11779639. 12760331.
KEGG	ekf:KO11_20000. eko:EKO11_3130.
PATRIC	48646283. VBIEscCol13896_3168.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K01785.
Enzyme and pathway databases
UniPathway	UPA00242.
Family and domain databases
Gene3D	2.70.98.10. 1 hit.
InterPro	IPR018052. Ald1_epimerase_CS. IPR013458. Ald_epimerase_bac. IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
PANTHER	PTHR10091. PTHR10091. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
PIRSF	PIRSF005096. GALM. 1 hit.
SUPFAM	SSF74650. Gal_mut_like. 1 hit.
TIGRFAMs	TIGR02636. galM_Leloir. 1 hit.
PROSITE	PS00545. ALDOSE_1_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E8Y5E4_ECOKO

Accession

Primary (citable) accession number: E8Y5E4

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)