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Protein

Multidrug resistance protein MdtG

Gene

mdtG

Organism
Rahnella sp. (strain Y9602)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciRSP741091:GHHP-3034-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Multidrug resistance protein MdtGUniRule annotation
Gene namesi
Name:mdtGUniRule annotation
Ordered Locus Names:Rahaq_2981
OrganismiRahnella sp. (strain Y9602)
Taxonomic identifieri741091 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeRahnella
Proteomesi
  • UP000007257 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 4021HelicalUniRule annotationAdd
BLAST
Transmembranei62 – 8221HelicalUniRule annotationAdd
BLAST
Transmembranei96 – 11621HelicalUniRule annotationAdd
BLAST
Transmembranei119 – 13921HelicalUniRule annotationAdd
BLAST
Transmembranei150 – 17021HelicalUniRule annotationAdd
BLAST
Transmembranei177 – 19721HelicalUniRule annotationAdd
BLAST
Transmembranei225 – 24521HelicalUniRule annotationAdd
BLAST
Transmembranei260 – 28021HelicalUniRule annotationAdd
BLAST
Transmembranei294 – 31421HelicalUniRule annotationAdd
BLAST
Transmembranei382 – 40221HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 412412Multidrug resistance protein MdtGPRO_0000414582Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi741091.Rahaq_2981.

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFITTMII.

Family and domain databases

HAMAPiMF_01528. MFS_MdtG.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8XY75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSASEPEIA PDPINWKRNL FVAWIGCFLT GAAFSLIMPF LPLYVETLGV
60 70 80 90 100
TGHESLNMWS GLVFSITFLF SAIASPFWGG LADRKGRKIM LLRSALGMSI
110 120 130 140 150
VMVLMGFAQN IWQFLILRAL LGLLGGFVPN ANALIATQIP RNKSGWALGT
160 170 180 190 200
LSTGGVSGAL LGPLVGGLLA DSYGLRPVFF ITASVLFLCF IMTLYFIREQ
210 220 230 240 250
FVPVSKKDML NRKQVFASLK NPKLVLCLFV TTMIIQVATG SIAPILTLYV
260 270 280 290 300
RELAGNTQNL AFISGMIASV PGVAALMSAP RLGKLGDRIG PERILVAMMA
310 320 330 340 350
LSVLLLIPMA LVQTPLQLGI LRFLLGACDG ALLPAVQTLL IYNCTNQVAG
360 370 380 390 400
RVFSYNQSFR DVGNVTGPLL GAAVSASYGF RTVFFVTAMV VLFNAGYSYW
410
CLQRRPHQAM ID
Length:412
Mass (Da):44,561
Last modified:April 5, 2011 - v1
Checksum:iC54E28D1D3B488AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002505 Genomic DNA. Translation: ADW74575.1.
RefSeqiWP_013576271.1. NC_015061.1.

Genome annotation databases

EnsemblBacteriaiADW74575; ADW74575; Rahaq_2981.
KEGGirah:Rahaq_2981.
PATRICi47404146. VBIRahSp167412_2963.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002505 Genomic DNA. Translation: ADW74575.1.
RefSeqiWP_013576271.1. NC_015061.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi741091.Rahaq_2981.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADW74575; ADW74575; Rahaq_2981.
KEGGirah:Rahaq_2981.
PATRICi47404146. VBIRahSp167412_2963.

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFITTMII.

Enzyme and pathway databases

BioCyciRSP741091:GHHP-3034-MONOMER.

Family and domain databases

HAMAPiMF_01528. MFS_MdtG.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Rahnella sp. Y9602."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Sobecky P.A., Martinez R.J., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y9602.

Entry informationi

Entry nameiMDTG_RAHSY
AccessioniPrimary (citable) accession number: E8XY75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: April 5, 2011
Last modified: November 11, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.