Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

2-hydroxy-3-oxopropionate reductase

Gene

Rahaq_0295

Organism
Rahnella sp. (strain Y9602)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei169 – 1691UniRule annotation

GO - Molecular functioni

  1. 2-hydroxy-3-oxopropionate reductase activity Source: UniProtKB-EC
  2. 3-hydroxyisobutyrate dehydrogenase activity Source: InterPro
  3. NAD binding Source: InterPro
  4. phosphogluconate dehydrogenase (decarboxylating) activity Source: InterPro

GO - Biological processi

  1. glyoxylate metabolic process Source: InterPro
  2. pentose-phosphate shunt Source: InterPro
  3. valine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciRSP741091:GHHP-296-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-hydroxy-3-oxopropionate reductaseImported (EC:1.1.1.60Imported)
Gene namesi
Ordered Locus Names:Rahaq_0295Imported
OrganismiRahnella sp. (strain Y9602)Imported
Taxonomic identifieri741091 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeRahnella
ProteomesiUP000007257: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE8XV59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000219608.
KOiK00042.
OMAiMVKRTFN.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR002204. 3-OH-isobutyrate_DH-rel_CS.
IPR008927. 6-PGluconate_DH_C-like.
IPR006115. 6PGDH_NADP-bd.
IPR013328. DH_multihelical.
IPR015815. HIBADH-type.
IPR016040. NAD(P)-bd_dom.
IPR029154. NADP-bd.
IPR006398. Tartro_sem_red.
[Graphical view]
PfamiPF14833. NAD_binding_11. 1 hit.
PF03446. NAD_binding_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000103. HIBADH. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR01505. tartro_sem_red. 1 hit.
PROSITEiPS00895. 3_HYDROXYISOBUT_DH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8XV59-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIGFIGLGI MGAPMAQHLV DAGHSLHFST LGNVPASLTD AGAKACATPA
60 70 80 90 100
EVTVHADVII IMVPDTPDVA TVLFGDNGCA SVPLKGKTIV DMSSISPIET
110 120 130 140 150
KTFAQRVQQL GGEYLDAPVS GGEIGAQQGT LTIMVGGKES VFNDIKPLFE
160 170 180 190 200
LMGKNITLVG DCGAGQTCKV ANQIIVALNI EAVSEALLFA SRAGADPARV
210 220 230 240 250
RQALMGGFAS SRILEVHGER MIKRTFAPGF KVALHQKDLN LALQSAKALS
260 270 280 290
ISLPNTATCQ ELFNVCAANG GSQLDHSSLI QSLEMMSNHK IG
Length:292
Mass (Da):30,407
Last modified:April 5, 2011 - v1
Checksum:iD96BF580E09268B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002505 Genomic DNA. Translation: ADW71925.1.
RefSeqiYP_004211052.1. NC_015061.1.

Genome annotation databases

EnsemblBacteriaiADW71925; ADW71925; Rahaq_0295.
GeneIDi10211255.
KEGGirah:Rahaq_0295.
PATRICi47398701. VBIRahSp167412_0299.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002505 Genomic DNA. Translation: ADW71925.1.
RefSeqiYP_004211052.1. NC_015061.1.

3D structure databases

ProteinModelPortaliE8XV59.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADW71925; ADW71925; Rahaq_0295.
GeneIDi10211255.
KEGGirah:Rahaq_0295.
PATRICi47398701. VBIRahSp167412_0299.

Phylogenomic databases

HOGENOMiHOG000219608.
KOiK00042.
OMAiMVKRTFN.

Enzyme and pathway databases

BioCyciRSP741091:GHHP-296-MONOMER.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR002204. 3-OH-isobutyrate_DH-rel_CS.
IPR008927. 6-PGluconate_DH_C-like.
IPR006115. 6PGDH_NADP-bd.
IPR013328. DH_multihelical.
IPR015815. HIBADH-type.
IPR016040. NAD(P)-bd_dom.
IPR029154. NADP-bd.
IPR006398. Tartro_sem_red.
[Graphical view]
PfamiPF14833. NAD_binding_11. 1 hit.
PF03446. NAD_binding_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000103. HIBADH. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR01505. tartro_sem_red. 1 hit.
PROSITEiPS00895. 3_HYDROXYISOBUT_DH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Rahnella sp. Y9602."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Sobecky P.A., Martinez R.J., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y9602Imported.

Entry informationi

Entry nameiE8XV59_RAHSY
AccessioniPrimary (citable) accession number: E8XV59
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: January 7, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.