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Protein

DNA ligase

Gene

AciX9_0660

Organism
Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciGTUN1198114:G12UY-650-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:AciX9_0660Imported
OrganismiGranulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)Imported
Taxonomic identifieri1198114 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeGranulicella
Proteomesi
  • UP000000343 Componenti: Chromosome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini386 – 549DNA_LIGASE_A3InterPro annotationAdd BLAST164

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036008
KOiK10747
OMAiWIKYKRD
OrthoDBiPOG091H09SJ

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

E8WZS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALFGAVAGL AEEMAGTASR LKKRAAIAAA ILAVHEELAE EVGLFCLYLA
60 70 80 90 100
GLPFAEADPR KLNAGGALLS KALLAVSGAT GEQLTAGYRK YGDMGAAGFD
110 120 130 140 150
LLQLHPTSQT RDMGHPLLLG DVRDAFAGMA TAKTTAIRAG LVEGLLRRAT
160 170 180 190 200
ALEAKYLLKL MLGDMRIGVK QSLVEEAIGV AAAAEVADVR HAVMLEADLG
210 220 230 240 250
GAAMRAFGGT LAEARMRLFH PLGFMLASPV ETPEEAIERF TAKPVKVAKA
260 270 280 290 300
KKSKKTEESD ELLVAEIEGA MLEDDKRTTE GTEGKERSTE ATVGVQAFLE
310 320 330 340 350
DKYDGMRAQL HFGDAEQVGR VAIYSRNRED ITESFPELCE AFSEASGELG
360 370 380 390 400
GLILDGEILG WDFQHGVALP FALLGQRIGR KKVGNEIRQQ VPVVFMAFDL
410 420 430 440 450
MFERGKLTLG LPLRERRRRL EEVVGALAEK AVSPLVLTEH AARRHEAQAR
460 470 480 490 500
MFGGDEEAEA GVARLMLSPS KLVESAEEID RAYADARARA NEGVMIKAAD
510 520 530 540 550
SVYLPGRRGL AWVKLKRELA TLDVVVTGAE FGQGRKAGTL SDYTFAVQTD
560 570 580 590 600
AGELLNVGKA YSGVTDAEIL ELTEFFKAHT LEDHGHSRTV EPLVIFEVAF
610 620 630 640 650
NNVMRSDRHA SGFALRFPRI LRIRTDKPLG EIDTVARVEE IYQSQVDKPK
660
DSAKAVKGSG QAVMGQLR
Length:668
Mass (Da):72,201
Last modified:April 5, 2011 - v1
Checksum:iA8600CB90CCE4272
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002480 Genomic DNA Translation: ADW67731.1
RefSeqiWP_013579059.1, NC_015064.1

Genome annotation databases

EnsemblBacteriaiADW67731; ADW67731; AciX9_0660
KEGGiacm:AciX9_0660

Similar proteinsi

Entry informationi

Entry nameiE8WZS0_GRATM
AccessioniPrimary (citable) accession number: E8WZS0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health