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Protein

DNA ligase

Gene

AciX9_0660

Organism
Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:AciX9_0660Imported
OrganismiGranulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)Imported
Taxonomic identifieri1198114 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeGranulicella
ProteomesiUP000000343 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8WZS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALFGAVAGL AEEMAGTASR LKKRAAIAAA ILAVHEELAE EVGLFCLYLA
60 70 80 90 100
GLPFAEADPR KLNAGGALLS KALLAVSGAT GEQLTAGYRK YGDMGAAGFD
110 120 130 140 150
LLQLHPTSQT RDMGHPLLLG DVRDAFAGMA TAKTTAIRAG LVEGLLRRAT
160 170 180 190 200
ALEAKYLLKL MLGDMRIGVK QSLVEEAIGV AAAAEVADVR HAVMLEADLG
210 220 230 240 250
GAAMRAFGGT LAEARMRLFH PLGFMLASPV ETPEEAIERF TAKPVKVAKA
260 270 280 290 300
KKSKKTEESD ELLVAEIEGA MLEDDKRTTE GTEGKERSTE ATVGVQAFLE
310 320 330 340 350
DKYDGMRAQL HFGDAEQVGR VAIYSRNRED ITESFPELCE AFSEASGELG
360 370 380 390 400
GLILDGEILG WDFQHGVALP FALLGQRIGR KKVGNEIRQQ VPVVFMAFDL
410 420 430 440 450
MFERGKLTLG LPLRERRRRL EEVVGALAEK AVSPLVLTEH AARRHEAQAR
460 470 480 490 500
MFGGDEEAEA GVARLMLSPS KLVESAEEID RAYADARARA NEGVMIKAAD
510 520 530 540 550
SVYLPGRRGL AWVKLKRELA TLDVVVTGAE FGQGRKAGTL SDYTFAVQTD
560 570 580 590 600
AGELLNVGKA YSGVTDAEIL ELTEFFKAHT LEDHGHSRTV EPLVIFEVAF
610 620 630 640 650
NNVMRSDRHA SGFALRFPRI LRIRTDKPLG EIDTVARVEE IYQSQVDKPK
660
DSAKAVKGSG QAVMGQLR
Length:668
Mass (Da):72,201
Last modified:April 5, 2011 - v1
Checksum:iA8600CB90CCE4272
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002480 Genomic DNA. Translation: ADW67731.1.
RefSeqiWP_013579059.1. NC_015064.1.
YP_004216511.1. NC_015064.1.

Genome annotation databases

EnsemblBacteriaiADW67731; ADW67731; AciX9_0660.
KEGGiacm:AciX9_0660.
PATRICi46818775. VBIAciSp155132_1310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002480 Genomic DNA. Translation: ADW67731.1.
RefSeqiWP_013579059.1. NC_015064.1.
YP_004216511.1. NC_015064.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADW67731; ADW67731; AciX9_0660.
KEGGiacm:AciX9_0660.
PATRICi46818775. VBIAciSp155132_1310.

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Acidobacterium sp. MP5ACTX9."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Rawat S.R., Mannisto M., Haggblom M.M., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MP5ACTX9Imported.

Entry informationi

Entry nameiE8WZS0_GRATM
AccessioniPrimary (citable) accession number: E8WZS0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 29, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.