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E8WVX0

- E8WVX0_GRATM

UniProt

E8WVX0 - E8WVX0_GRATM

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Protein

Alanine racemase

Gene

AciX9_3728

Organism
Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei32 – 321Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei128 – 1281SubstrateUniRule annotation
Active sitei276 – 2761Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei325 – 3251Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:AciX9_3728Imported
OrganismiGranulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9)Imported
Taxonomic identifieri1198114 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeGranulicella
ProteomesiUP000000343: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei32 – 321N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE8WVX0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

E8WVX0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNWTEIDAA ALTANYKAIQ RVAGAEVLAV IKARAYGHGA ERCAPILVRA
60 70 80 90 100
GARWLGVTCA SEGQQVRAAL DHAGLEADIL VMSGSLPKDV PAIVSAHLIP
110 120 130 140 150
VIWTTDHIDL LAGIGCRVHV EVDTGMGRQG VRPGQDLATL LARISAAGLR
160 170 180 190 200
LDGLFTHFCS SEVANSNLTL RQRALFEAAV QQTVTAGLTP AWLHAANSSA
210 220 230 240 250
VDNETPEPSS GDWLTTLAAA AGSQTMVRTG LALYGYCLPI EGGALHHLSP
260 270 280 290 300
ALQPVLTWKA RILAVRDLAP GDTVGYNATF IAGPAMKVAL LPVGYADGLR
310 320 330 340 350
RELSHPHGWV MVQGHPAPIL GRISMNLTVV DVTAIPAASA GDEATLLGPG
360 370
ITAEDHARLA RTISYEILCG IHPCG
Length:375
Mass (Da):39,265
Last modified:April 5, 2011 - v1
Checksum:iFBEE7E5E8A758D85
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002480 Genomic DNA. Translation: ADW70729.1.
RefSeqiYP_004219509.1. NC_015064.1.

Genome annotation databases

EnsemblBacteriaiADW70729; ADW70729; AciX9_3728.
GeneIDi10205752.
KEGGiacm:AciX9_3728.
PATRICi46825001. VBIAciSp155132_4372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002480 Genomic DNA. Translation: ADW70729.1 .
RefSeqi YP_004219509.1. NC_015064.1.

3D structure databases

ProteinModelPortali E8WVX0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADW70729 ; ADW70729 ; AciX9_3728 .
GeneIDi 10205752.
KEGGi acm:AciX9_3728.
PATRICi 46825001. VBIAciSp155132_4372.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Acidobacterium sp. MP5ACTX9."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Rawat S.R., Mannisto M., Haggblom M.M., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MP5ACTX9Imported.

Entry informationi

Entry nameiE8WVX0_GRATM
AccessioniPrimary (citable) accession number: E8WVX0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3