Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

E8WVX0 (E8WVX0_ACISM) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:AciX9_3728 EMBL ADW70729.1
OrganismAcidobacterium sp. (strain MP5ACTX9) [Complete proteome] [HAMAP]
Taxonomic identifier696844 [NCBI]
Taxonomic lineageBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium

Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site321Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2761Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1281Substrate By similarity HAMAP-Rule MF_01201
Binding site3251Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue321N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E8WVX0 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: FBEE7E5E8A758D85

FASTA37539,265
        10         20         30         40         50         60 
MNNWTEIDAA ALTANYKAIQ RVAGAEVLAV IKARAYGHGA ERCAPILVRA GARWLGVTCA 

        70         80         90        100        110        120 
SEGQQVRAAL DHAGLEADIL VMSGSLPKDV PAIVSAHLIP VIWTTDHIDL LAGIGCRVHV 

       130        140        150        160        170        180 
EVDTGMGRQG VRPGQDLATL LARISAAGLR LDGLFTHFCS SEVANSNLTL RQRALFEAAV 

       190        200        210        220        230        240 
QQTVTAGLTP AWLHAANSSA VDNETPEPSS GDWLTTLAAA AGSQTMVRTG LALYGYCLPI 

       250        260        270        280        290        300 
EGGALHHLSP ALQPVLTWKA RILAVRDLAP GDTVGYNATF IAGPAMKVAL LPVGYADGLR 

       310        320        330        340        350        360 
RELSHPHGWV MVQGHPAPIL GRISMNLTVV DVTAIPAASA GDEATLLGPG ITAEDHARLA 

       370 
RTISYEILCG IHPCG 

« Hide

References

[1]"Complete sequence of chromosome of Acidobacterium sp. MP5ACTX9."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Rawat S.R., Mannisto M., Haggblom M.M., Woyke T.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MP5ACTX9.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002480 Genomic DNA. Translation: ADW70729.1.
RefSeqYP_004219509.1. NC_015064.1.

3D structure databases

ProteinModelPortalE8WVX0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADW70729; ADW70729; AciX9_3728.
GeneID10205752.
KEGGacm:AciX9_3728.
PATRIC46825001. VBIAciSp155132_4372.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE8WVX0_ACISM
AccessionPrimary (citable) accession number: E8WVX0
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 19, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)