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E8WVX0

- E8WVX0_ACISM

UniProt

E8WVX0 - E8WVX0_ACISM

Protein

Alanine racemase

Gene

AciX9_3728

Organism
Acidobacterium sp. (strain MP5ACTX9)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 28 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei32 – 321Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei128 – 1281SubstrateUniRule annotation
    Active sitei276 – 2761Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei325 – 3251Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:AciX9_3728Imported
    OrganismiAcidobacterium sp. (strain MP5ACTX9)Imported
    Taxonomic identifieri696844 [NCBI]
    Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeAcidobacterium
    ProteomesiUP000000343: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei32 – 321N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE8WVX0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E8WVX0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNNWTEIDAA ALTANYKAIQ RVAGAEVLAV IKARAYGHGA ERCAPILVRA    50
    GARWLGVTCA SEGQQVRAAL DHAGLEADIL VMSGSLPKDV PAIVSAHLIP 100
    VIWTTDHIDL LAGIGCRVHV EVDTGMGRQG VRPGQDLATL LARISAAGLR 150
    LDGLFTHFCS SEVANSNLTL RQRALFEAAV QQTVTAGLTP AWLHAANSSA 200
    VDNETPEPSS GDWLTTLAAA AGSQTMVRTG LALYGYCLPI EGGALHHLSP 250
    ALQPVLTWKA RILAVRDLAP GDTVGYNATF IAGPAMKVAL LPVGYADGLR 300
    RELSHPHGWV MVQGHPAPIL GRISMNLTVV DVTAIPAASA GDEATLLGPG 350
    ITAEDHARLA RTISYEILCG IHPCG 375
    Length:375
    Mass (Da):39,265
    Last modified:April 5, 2011 - v1
    Checksum:iFBEE7E5E8A758D85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002480 Genomic DNA. Translation: ADW70729.1.
    RefSeqiYP_004219509.1. NC_015064.1.

    Genome annotation databases

    EnsemblBacteriaiADW70729; ADW70729; AciX9_3728.
    GeneIDi10205752.
    KEGGiacm:AciX9_3728.
    PATRICi46825001. VBIAciSp155132_4372.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002480 Genomic DNA. Translation: ADW70729.1 .
    RefSeqi YP_004219509.1. NC_015064.1.

    3D structure databases

    ProteinModelPortali E8WVX0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADW70729 ; ADW70729 ; AciX9_3728 .
    GeneIDi 10205752.
    KEGGi acm:AciX9_3728.
    PATRICi 46825001. VBIAciSp155132_4372.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Acidobacterium sp. MP5ACTX9."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Rawat S.R., Mannisto M., Haggblom M.M., Woyke T.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MP5ACTX9Imported.

    Entry informationi

    Entry nameiE8WVX0_ACISM
    AccessioniPrimary (citable) accession number: E8WVX0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3