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E8WTK5

- E8WTK5_GEOS8

UniProt

E8WTK5 - E8WTK5_GEOS8

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Protein
Elongation factor Tu
Gene
tuf, GM18_0817, GM18_0830
Organism
Geobacter sp. (strain M18)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. nucleotidyltransferase activity Source: UniProtKB-KW
  4. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported, NucleotidyltransferaseImported, Transferase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciGSP443143:GHZL-837-MONOMER.
    GSP443143:GHZL-851-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:GM18_0817Imported, GM18_0830Imported
    OrganismiGeobacter sp. (strain M18)Imported
    Taxonomic identifieri443143 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
    ProteomesiUP000001442: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E8WTK5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKAKFERTK PHVNIGTIGH VDHGKTTLTA AITKVLAGKG QAEFKAFDQI    50
    DNAPEERERG ITIATAHVEY ETDKRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVVSAAD GPMPQTREHI LLARQVGVPY IVVFLNKADM VDDEELLELV 150
    ELEVRELLSS YDFPGDDIPI IKGSALKGLE GDKGELGEEA ILKLMDAVDS 200
    YIPEPVRAID KPFLMPVEDV FSISGRGTVA TGRVERGIVK VGEEVEIVGM 250
    KATTKTTVTG VEMFRKLLDE GRAGDNIGAL LRGVKREDIE RGQVLAKPGS 300
    ITPHTKFKAE AYILSKEEGG RHTPFFNGYR PQFYFRTTDV TGVVDLEAGV 350
    EMVMPGDNVS VVVNLITPIA MDEGLRFAIR EGGRTVGAGV VASIIE 396
    Length:396
    Mass (Da):43,008
    Last modified:April 5, 2011 - v1
    Checksum:iEB6D910757AF60AE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002479 Genomic DNA. Translation: ADW12296.1.
    CP002479 Genomic DNA. Translation: ADW12309.1.
    RefSeqiWP_015719165.1. NC_014973.1.
    YP_004197572.1. NC_014973.1.
    YP_004197585.1. NC_014973.1.

    Genome annotation databases

    EnsemblBacteriaiADW12296; ADW12296; GM18_0817.
    ADW12309; ADW12309; GM18_0830.
    GeneIDi10196397.
    10196411.
    KEGGigeb:GM18_0817.
    geb:GM18_0830.
    PATRICi46945513. VBIGeoSp68312_0816.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002479 Genomic DNA. Translation: ADW12296.1 .
    CP002479 Genomic DNA. Translation: ADW12309.1 .
    RefSeqi WP_015719165.1. NC_014973.1.
    YP_004197572.1. NC_014973.1.
    YP_004197585.1. NC_014973.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADW12296 ; ADW12296 ; GM18_0817 .
    ADW12309 ; ADW12309 ; GM18_0830 .
    GeneIDi 10196397.
    10196411.
    KEGGi geb:GM18_0817.
    geb:GM18_0830.
    PATRICi 46945513. VBIGeoSp68312_0816.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.

    Enzyme and pathway databases

    BioCyci GSP443143:GHZL-837-MONOMER.
    GSP443143:GHZL-851-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: M18Imported.

    Entry informationi

    Entry nameiE8WTK5_GEOS8
    AccessioniPrimary (citable) accession number: E8WTK5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: September 3, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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