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E8WTK5

- E8WTK5_GEOS8

UniProt

E8WTK5 - E8WTK5_GEOS8

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Protein

Elongation factor Tu

Gene

tuf

Organism
Geobacter sp. (strain M18)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. nucleotidyltransferase activity Source: UniProtKB-KW
  4. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation, NucleotidyltransferaseImported, Transferase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciGSP443143:GHZL-837-MONOMER.
GSP443143:GHZL-851-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:GM18_0817Imported, GM18_0830Imported
OrganismiGeobacter sp. (strain M18)Imported
Taxonomic identifieri443143 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000001442: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiGTEMCMP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8WTK5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKAKFERTK PHVNIGTIGH VDHGKTTLTA AITKVLAGKG QAEFKAFDQI
60 70 80 90 100
DNAPEERERG ITIATAHVEY ETDKRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVVSAAD GPMPQTREHI LLARQVGVPY IVVFLNKADM VDDEELLELV
160 170 180 190 200
ELEVRELLSS YDFPGDDIPI IKGSALKGLE GDKGELGEEA ILKLMDAVDS
210 220 230 240 250
YIPEPVRAID KPFLMPVEDV FSISGRGTVA TGRVERGIVK VGEEVEIVGM
260 270 280 290 300
KATTKTTVTG VEMFRKLLDE GRAGDNIGAL LRGVKREDIE RGQVLAKPGS
310 320 330 340 350
ITPHTKFKAE AYILSKEEGG RHTPFFNGYR PQFYFRTTDV TGVVDLEAGV
360 370 380 390
EMVMPGDNVS VVVNLITPIA MDEGLRFAIR EGGRTVGAGV VASIIE
Length:396
Mass (Da):43,008
Last modified:April 5, 2011 - v1
Checksum:iEB6D910757AF60AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002479 Genomic DNA. Translation: ADW12296.1.
CP002479 Genomic DNA. Translation: ADW12309.1.
RefSeqiWP_015719165.1. NC_014973.1.
YP_004197572.1. NC_014973.1.
YP_004197585.1. NC_014973.1.

Genome annotation databases

EnsemblBacteriaiADW12296; ADW12296; GM18_0817.
ADW12309; ADW12309; GM18_0830.
GeneIDi10196397.
10196411.
KEGGigeb:GM18_0817.
geb:GM18_0830.
PATRICi46945513. VBIGeoSp68312_0816.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002479 Genomic DNA. Translation: ADW12296.1 .
CP002479 Genomic DNA. Translation: ADW12309.1 .
RefSeqi WP_015719165.1. NC_014973.1.
YP_004197572.1. NC_014973.1.
YP_004197585.1. NC_014973.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADW12296 ; ADW12296 ; GM18_0817 .
ADW12309 ; ADW12309 ; GM18_0830 .
GeneIDi 10196397.
10196411.
KEGGi geb:GM18_0817.
geb:GM18_0830.
PATRICi 46945513. VBIGeoSp68312_0816.

Phylogenomic databases

HOGENOMi HOG000229290.
KOi K02358.
OMAi GTEMCMP.

Enzyme and pathway databases

BioCyci GSP443143:GHZL-837-MONOMER.
GSP443143:GHZL-851-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M18Imported.

Entry informationi

Entry nameiE8WTK5_GEOS8
AccessioniPrimary (citable) accession number: E8WTK5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 26, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3