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E8WM84

- E8WM84_GEOS8

UniProt

E8WM84 - E8WM84_GEOS8

Protein
Submitted name:

2-isopropylmalate synthase/homocitrate synthase family protein

Gene

GM18_1123

Organism
Geobacter sp. (strain M18)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 2-isopropylmalate synthase activity Source: InterPro

    GO - Biological processi

    1. leucine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Enzyme and pathway databases

    BioCyciGSP443143:GHZL-1154-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2-isopropylmalate synthase/homocitrate synthase family proteinImported (EC:2.3.1.182Imported)
    Gene namesi
    Ordered Locus Names:GM18_1123Imported
    OrganismiGeobacter sp. (strain M18)Imported
    Taxonomic identifieri443143 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
    ProteomesiUP000001442: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE8WM84.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alpha-IPM synthase/homocitrate synthase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000046860.
    KOiK01649.
    OMAiDGAQTNG.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013709. 2-isopropylmalate_synth_dimer.
    IPR002034. AIPM/Hcit_synth_CS.
    IPR013785. Aldolase_TIM.
    IPR005675. LeuA-rel.
    IPR000891. PYR_CT.
    [Graphical view]
    PANTHERiPTHR10277:SF5. PTHR10277:SF5. 1 hit.
    PfamiPF00682. HMGL-like. 1 hit.
    PF08502. LeuA_dimer. 1 hit.
    [Graphical view]
    SMARTiSM00917. LeuA_dimer. 1 hit.
    [Graphical view]
    SUPFAMiSSF110921. SSF110921. 1 hit.
    TIGRFAMsiTIGR00977. LeuA_rel. 1 hit.
    PROSITEiPS00815. AIPM_HOMOCIT_SYNTH_1. 1 hit.
    PS50991. PYR_CT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E8WM84-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLVKLYDTT LRDGTQAEDI SFLVEDKIRI AHKLDECGIH YIEGGWPGSN    50
    PKDVAFFKDI KKEKLSQAKI AAFGSTRRAK ITPDKDQNLR TLVDSKADAA 100
    TIFGKSWDFQ VHEALRIPLE ENLEMIFDSL EYLKGHMPEV FYDAEHFFDG 150
    YKSNPEYAIK TLQAAQQAGA DCIILCDTNG GSMPYEIARI VNEVKKSITT 200
    PLGVHAHNDG ECAVANTIIS VEQGIVHVQG TINGFGERCG NANLCSIIPA 250
    LKVKMKRDCI SDAQMRTLRE LSRYVYELAN LAPNKHQPYV GNSAFAHKGG 300
    VHVSAIQRHP ETYEHMRPEL VGNTTRVLVS DLSGRANILA KATEFNINLD 350
    SKDPVTLEIL EDIKSMENRG YQFEGAEASF ELLMKRALGT HRKFFSVIGF 400
    RVIDEKRSED DQPISEATIK VKVGGKIEHT ASEGHGPVNA LDNALRKALE 450
    KFYPRLKDVK LHDYKVRVLP AGQGTASSIR VLIESGDKEG RWGTVGVSSN 500
    VIEASYQALV DAIEFKLHKD EETAAPKK 528
    Length:528
    Mass (Da):58,642
    Last modified:April 5, 2011 - v1
    Checksum:iDCC80117B9F71451
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002479 Genomic DNA. Translation: ADW12598.1.
    RefSeqiWP_015719458.1. NC_014973.1.
    YP_004197874.1. NC_014973.1.

    Genome annotation databases

    EnsemblBacteriaiADW12598; ADW12598; GM18_1123.
    GeneIDi10196714.
    KEGGigeb:GM18_1123.
    PATRICi46946144. VBIGeoSp68312_1119.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002479 Genomic DNA. Translation: ADW12598.1 .
    RefSeqi WP_015719458.1. NC_014973.1.
    YP_004197874.1. NC_014973.1.

    3D structure databases

    ProteinModelPortali E8WM84.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADW12598 ; ADW12598 ; GM18_1123 .
    GeneIDi 10196714.
    KEGGi geb:GM18_1123.
    PATRICi 46946144. VBIGeoSp68312_1119.

    Phylogenomic databases

    HOGENOMi HOG000046860.
    KOi K01649.
    OMAi DGAQTNG.

    Enzyme and pathway databases

    BioCyci GSP443143:GHZL-1154-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013709. 2-isopropylmalate_synth_dimer.
    IPR002034. AIPM/Hcit_synth_CS.
    IPR013785. Aldolase_TIM.
    IPR005675. LeuA-rel.
    IPR000891. PYR_CT.
    [Graphical view ]
    PANTHERi PTHR10277:SF5. PTHR10277:SF5. 1 hit.
    Pfami PF00682. HMGL-like. 1 hit.
    PF08502. LeuA_dimer. 1 hit.
    [Graphical view ]
    SMARTi SM00917. LeuA_dimer. 1 hit.
    [Graphical view ]
    SUPFAMi SSF110921. SSF110921. 1 hit.
    TIGRFAMsi TIGR00977. LeuA_rel. 1 hit.
    PROSITEi PS00815. AIPM_HOMOCIT_SYNTH_1. 1 hit.
    PS50991. PYR_CT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: M18Imported.

    Entry informationi

    Entry nameiE8WM84_GEOS8
    AccessioniPrimary (citable) accession number: E8WM84
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3