E8WM84 (E8WM84_GEOS8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-isopropylmalate synthase/homocitrate synthase family protein EMBL ADW12598.1
EC=2.3.1.182 EMBL ADW12598.1

Gene names

Ordered Locus Names:

GM18_1123

Organism

Geobacter sp. (strain M18) [Complete proteome] [HAMAP] EMBL ADW12598.1

Taxonomic identifier

443143 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	528 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the alpha-IPM synthase/homocitrate synthase family. RuleBase RU003523

Ontologies

Keywords
Molecular function	Acyltransferase EMBL ADW12598.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	leucine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	2-isopropylmalate synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E8WM84 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: DCC80117B9F71451	FASTA	528	58,642
	10 20 30 40 50 60 MSLVKLYDTT LRDGTQAEDI SFLVEDKIRI AHKLDECGIH YIEGGWPGSN PKDVAFFKDI 70 80 90 100 110 120 KKEKLSQAKI AAFGSTRRAK ITPDKDQNLR TLVDSKADAA TIFGKSWDFQ VHEALRIPLE 130 140 150 160 170 180 ENLEMIFDSL EYLKGHMPEV FYDAEHFFDG YKSNPEYAIK TLQAAQQAGA DCIILCDTNG 190 200 210 220 230 240 GSMPYEIARI VNEVKKSITT PLGVHAHNDG ECAVANTIIS VEQGIVHVQG TINGFGERCG 250 260 270 280 290 300 NANLCSIIPA LKVKMKRDCI SDAQMRTLRE LSRYVYELAN LAPNKHQPYV GNSAFAHKGG 310 320 330 340 350 360 VHVSAIQRHP ETYEHMRPEL VGNTTRVLVS DLSGRANILA KATEFNINLD SKDPVTLEIL 370 380 390 400 410 420 EDIKSMENRG YQFEGAEASF ELLMKRALGT HRKFFSVIGF RVIDEKRSED DQPISEATIK 430 440 450 460 470 480 VKVGGKIEHT ASEGHGPVNA LDNALRKALE KFYPRLKDVK LHDYKVRVLP AGQGTASSIR 490 500 510 520 VLIESGDKEG RWGTVGVSSN VIEASYQALV DAIEFKLHKD EETAAPKK

References

[1]

"Complete sequence of Geobacter sp. M18." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Munk C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Holmes D. , Aklujkar M., Lovley D., Woyke T. Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: M18.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002479 Genomic DNA. Translation: ADW12598.1.
RefSeq	YP_004197874.1. NC_014973.1.
3D structure databases
ProteinModelPortal	E8WM84.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADW12598; ADW12598; GM18_1123.
GeneID	10196714.
KEGG	geb:GM18_1123.
PATRIC	46946144. VBIGeoSp68312_1119.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000046860.
KO	K01649.
Enzyme and pathway databases
BioCyc	GSP443143:GHZL-1154-MONOMER.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
InterPro	IPR013709. 2-isopropylmalate_synth_dimer. IPR002034. AIPM/Hcit_synth_CS. IPR013785. Aldolase_TIM. IPR005675. LeuA-rel. IPR000891. PYR_CT. [Graphical view]
PANTHER	PTHR10277:SF5. PTHR10277:SF5. 1 hit.
Pfam	PF00682. HMGL-like. 1 hit. PF08502. LeuA_dimer. 1 hit. [Graphical view]
SMART	SM00917. LeuA_dimer. 1 hit. [Graphical view]
SUPFAM	SSF110921. 2-isopropylmalate_synth_dimer. 1 hit.
TIGRFAMs	TIGR00977. LeuA_rel. 1 hit.
PROSITE	PS00815. AIPM_HOMOCIT_SYNTH_1. 1 hit. PS50991. PYR_CT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E8WM84_GEOS8

Accession

Primary (citable) accession number: E8WM84

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)