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Protein

Glutamate decarboxylase

Gene

Sfla_3455

Organism
Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Sfla_3455Imported
OrganismiStreptomyces pratensis (strain ATCC 33331 / IAF-45CD)Imported
Taxonomic identifieri591167 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000002066 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei287N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi591167.Sfla_3455

Structurei

3D structure databases

ProteinModelPortaliE8WG52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

E8WG52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALHQGRHGR PAPSEEHRRL ALNPFFGEAD PTAPMVAAPP THRLPEDPLP
60 70 80 90 100
PSTAYRLVHD ELMLDGNSRL NLATFVTTWM EPQAGVLMSE CRDKNMIDKD
110 120 130 140 150
EYPRTAELER RCVAMLADLW NAPDPASTVG CSTTGSSEAC MLAGMALKRR
160 170 180 190 200
WSARNADRYP ATARPNLVMG VNVQVCWEKF CTFWEVEPRQ VPMDGERFHL
210 220 230 240 250
DPQAAAELCD ENTIGVVGIL GSTFDGSYEP IADLCAALDD LQERTGLDIP
260 270 280 290 300
VHVDGASGAM IAPFLDPDLV WDFRLPRVSS INTSGHKYGL VYPGVGWALW
310 320 330 340 350
RSQAELPEEL VFRVNYLGGD MPTFALNFSR PGAQVVAQYY TFLRLGREGY
360 370 380 390 400
RAVQQASRDI ARRLAVQFEA LEDFRLLTRG DELPVFAVTT KPDVQAYDVF
410 420 430 440 450
DVSRRLRERG WLVPAYTFPA NRQDLSVLRV VCRNGFSSDL AELLLDDLRG
460 470
LLPELRSQAH PLHRDPGVQT AFHH
Length:474
Mass (Da):52,985
Last modified:April 5, 2011 - v1
Checksum:i3F72C8988DC79935
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002475 Genomic DNA Translation: ADW04875.1
RefSeqiWP_014155495.1, NC_016114.1

Genome annotation databases

EnsemblBacteriaiADW04875; ADW04875; Sfla_3455
KEGGisfa:Sfla_3455
PATRICifig|591167.6.peg.3529

Similar proteinsi

Entry informationi

Entry nameiE8WG52_STRFA
AccessioniPrimary (citable) accession number: E8WG52
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health