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E8WFP2 (E8WFP2_STRFA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length539 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. RuleBase RU000555

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. RuleBase RU000555

Sequence similarities

Belongs to the malate synthase family. RuleBase RU000555

Ontologies

Keywords
   Biological processGlyoxylate bypass RuleBase RU000555
Tricarboxylic acid cycle RuleBase RU000555
   Molecular functionAcyltransferase EMBL ADW02490.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1691Proton acceptor By similarity PIRSR PIRSR001363-1
Active site4531Proton donor By similarity PIRSR PIRSR001363-1

Sequences

Sequence LengthMass (Da)Tools
E8WFP2 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: DACA73566F71A31F

FASTA53959,891
        10         20         30         40         50         60 
MSAPAPSPLA IVDAEPLPRQ DEVLTDAALA FVAELHRRFT PRRDELLARR GERRAEIART 

        70         80         90        100        110        120 
STLDFLPETE AVRVDDTWKV APAPAALDDR RVEITGPTDR KMTVNALNSG ARVWLADFED 

       130        140        150        160        170        180 
ASAPTWENVV TGQLNLIDAY TRNIDFTDPR SGKSYALKPA EELATVVTRP RGWHLDERHL 

       190        200        210        220        230        240 
QLDGTPVPGA LVDFGLYFFH NAQRLIDLGK GPYFYLPKTE SYLEARLWND IFVFAQDYVG 

       250        260        270        280        290        300 
IPQGTVRATV LIETITAAYE MEEILYELRD HASGLNAGRW DYLFSIVKNF RDGGSKFVLP 

       310        320        330        340        350        360 
DRNLVTMTAP FMRAYTELLV RTCHKRGAHA IGGMAAFIPS RRDAEVNKVA FEKVKADKDR 

       370        380        390        400        410        420 
EAGDGFDGSW VAHPDLVPIA MASFDAVLGA KPNQKDRLRE DVSVAAGDLI AIDTLDAKPS 

       430        440        450        460        470        480 
YDGLRNAVAV GIRYIEAWLR GMGAVAIFNL MEDAATAEIS RSQIWQWINA DVVFENGEHA 

       490        500        510        520        530 
TSDLARKVAA EELAAIRAEV GDETFEAGKW QQAHDLLLQV SLDQDYADFL TLPAYEQLG 

« Hide

References

[1]"Complete sequence of chromosome of Streptomyces flavogriseus ATCC 33331."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P., Mead D., Woyke T.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33331 / DSM 40990 / IAF-45CD.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002475 Genomic DNA. Translation: ADW02490.1.
RefSeqYP_004922007.1. NC_016114.1.

3D structure databases

ProteinModelPortalE8WFP2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADW02490; ADW02490; Sfla_1036.
GeneID11372123.
KEGGsfa:Sfla_1036.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01638.

Enzyme and pathway databases

BioCycSFLA591167:GI5Y-1040-MONOMER.
UniPathwayUPA00703; UER00720.

Family and domain databases

InterProIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF001363. Malate_synth. 1 hit.
SUPFAMSSF51645. SSF51645. 1 hit.
TIGRFAMsTIGR01344. malate_syn_A. 1 hit.
PROSITEPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8WFP2_STRFA
AccessionPrimary (citable) accession number: E8WFP2
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)