Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E8WFP2

- E8WFP2_STRFA

UniProt

E8WFP2 - E8WFP2_STRFA

Protein

Malate synthase

Gene

Sfla_1036

Organism
Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei169 – 1691Proton acceptorUniRule annotation
    Active sitei453 – 4531Proton donorUniRule annotation

    GO - Molecular functioni

    1. malate synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-UniPathway
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Enzyme and pathway databases

    BioCyciSFLA591167:GI5Y-1040-MONOMER.
    UniPathwayiUPA00703; UER00720.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Malate synthaseUniRule annotation (EC:2.3.3.9UniRule annotation)
    Gene namesi
    Ordered Locus Names:Sfla_1036Imported
    OrganismiStreptomyces pratensis (strain ATCC 33331 / IAF-45CD)Imported
    Taxonomic identifieri591167 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000002066: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE8WFP2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the malate synthase family.UniRule annotation

    Phylogenomic databases

    KOiK01638.

    Family and domain databases

    InterProiIPR011076. Malate_synth-like.
    IPR006252. Malate_synthA.
    IPR001465. Malate_synthase.
    IPR019830. Malate_synthase_CS.
    [Graphical view]
    PfamiPF01274. Malate_synthase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001363. Malate_synth. 1 hit.
    SUPFAMiSSF51645. SSF51645. 1 hit.
    TIGRFAMsiTIGR01344. malate_syn_A. 1 hit.
    PROSITEiPS00510. MALATE_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E8WFP2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAPAPSPLA IVDAEPLPRQ DEVLTDAALA FVAELHRRFT PRRDELLARR    50
    GERRAEIART STLDFLPETE AVRVDDTWKV APAPAALDDR RVEITGPTDR 100
    KMTVNALNSG ARVWLADFED ASAPTWENVV TGQLNLIDAY TRNIDFTDPR 150
    SGKSYALKPA EELATVVTRP RGWHLDERHL QLDGTPVPGA LVDFGLYFFH 200
    NAQRLIDLGK GPYFYLPKTE SYLEARLWND IFVFAQDYVG IPQGTVRATV 250
    LIETITAAYE MEEILYELRD HASGLNAGRW DYLFSIVKNF RDGGSKFVLP 300
    DRNLVTMTAP FMRAYTELLV RTCHKRGAHA IGGMAAFIPS RRDAEVNKVA 350
    FEKVKADKDR EAGDGFDGSW VAHPDLVPIA MASFDAVLGA KPNQKDRLRE 400
    DVSVAAGDLI AIDTLDAKPS YDGLRNAVAV GIRYIEAWLR GMGAVAIFNL 450
    MEDAATAEIS RSQIWQWINA DVVFENGEHA TSDLARKVAA EELAAIRAEV 500
    GDETFEAGKW QQAHDLLLQV SLDQDYADFL TLPAYEQLG 539
    Length:539
    Mass (Da):59,891
    Last modified:April 5, 2011 - v1
    Checksum:iDACA73566F71A31F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002475 Genomic DNA. Translation: ADW02490.1.
    RefSeqiYP_004922007.1. NC_016114.1.

    Genome annotation databases

    EnsemblBacteriaiADW02490; ADW02490; Sfla_1036.
    GeneIDi11372123.
    KEGGisfa:Sfla_1036.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002475 Genomic DNA. Translation: ADW02490.1 .
    RefSeqi YP_004922007.1. NC_016114.1.

    3D structure databases

    ProteinModelPortali E8WFP2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADW02490 ; ADW02490 ; Sfla_1036 .
    GeneIDi 11372123.
    KEGGi sfa:Sfla_1036.

    Phylogenomic databases

    KOi K01638.

    Enzyme and pathway databases

    UniPathwayi UPA00703 ; UER00720 .
    BioCyci SFLA591167:GI5Y-1040-MONOMER.

    Family and domain databases

    InterProi IPR011076. Malate_synth-like.
    IPR006252. Malate_synthA.
    IPR001465. Malate_synthase.
    IPR019830. Malate_synthase_CS.
    [Graphical view ]
    Pfami PF01274. Malate_synthase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001363. Malate_synth. 1 hit.
    SUPFAMi SSF51645. SSF51645. 1 hit.
    TIGRFAMsi TIGR01344. malate_syn_A. 1 hit.
    PROSITEi PS00510. MALATE_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Streptomyces flavogriseus ATCC 33331."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P., Mead D., Woyke T.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33331 / DSM 40990 / IAF-45CDImported.

    Entry informationi

    Entry nameiE8WFP2_STRFA
    AccessioniPrimary (citable) accession number: E8WFP2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3