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Protein

Aldose 1-epimerase

Gene

Sfla_4416

Organism
Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciSFLA591167:GI5Y-4487-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Ordered Locus Names:Sfla_4416Imported
OrganismiStreptomyces pratensis (strain ATCC 33331 / IAF-45CD)Imported
Taxonomic identifieri591167 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000002066 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333 PotentialImportedAdd
BLAST
Chaini34 – 388355 PotentialImportedPRO_5000701563Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliE8WD38.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

KOiK01785.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006311. TAT_signal.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E8WD38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFSTGTSRR TVLAATAAAG LAVAAGAPAA HASATGRAPS KELFGTLADG
60 70 80 90 100
TEVHRWTLAN GGTRLKVLSW GGVVQSLEVP DRRGRTANVS LGFGGLPDYV
110 120 130 140 150
AKSPYFGGLI GRYGNRIAGG RFTLDGVTHQ LPVNDGPNSL HGGDQGFDKR
160 170 180 190 200
VWDVRPFTGR GDVGLVLTRT SPDGEAGYPG SLAVRVVYTL TSRGEWRVDY
210 220 230 240 250
TATTDRATVL NLTSHTYFNL AGEGSGSADG HLLELAAARY TPVDATLIPT
260 270 280 290 300
GELAPVARTP FDFRRSRALG EAVRTPHEQI GYGQGIDHNY VLDKGTTARP
310 320 330 340 350
EYALTVTDPG SGRVMKMYTT EPGMQVYTGN FLDGTLTGTS GRVYRQGDAF
360 370 380
CLESQHFPDS PNQPSFPSTV LRPGDTYRST TVHAFSAR
Length:388
Mass (Da):41,245
Last modified:April 4, 2011 - v1
Checksum:iED9BDF59914E2434
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002475 Genomic DNA. Translation: ADW05823.1.
RefSeqiYP_004925340.1. NC_016114.1.

Genome annotation databases

EnsemblBacteriaiADW05823; ADW05823; Sfla_4416.
KEGGisfa:Sfla_4416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002475 Genomic DNA. Translation: ADW05823.1.
RefSeqiYP_004925340.1. NC_016114.1.

3D structure databases

ProteinModelPortaliE8WD38.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADW05823; ADW05823; Sfla_4416.
KEGGisfa:Sfla_4416.

Phylogenomic databases

KOiK01785.

Enzyme and pathway databases

UniPathwayiUPA00242.
BioCyciSFLA591167:GI5Y-4487-MONOMER.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006311. TAT_signal.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS51318. TAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Streptomyces flavogriseus ATCC 33331."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P., Mead D., Woyke T.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33331 / DSM 40990 / IAF-45CDImported.

Entry informationi

Entry nameiE8WD38_STRFA
AccessioniPrimary (citable) accession number: E8WD38
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2011
Last sequence update: April 4, 2011
Last modified: March 31, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.