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E8W331

- E8W331_STRFA

UniProt

E8W331 - E8W331_STRFA

Protein

Beta-galactosidase

Gene

Sfla_4952

Organism
Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei118 – 1181Substrate
    Metal bindingi122 – 1221ZincUniRule annotation
    Binding sitei156 – 1561SubstrateUniRule annotation
    Active sitei157 – 1571Proton donorUniRule annotation
    Metal bindingi165 – 1651ZincUniRule annotation
    Metal bindingi167 – 1671ZincUniRule annotation
    Metal bindingi170 – 1701ZincUniRule annotation
    Active sitei316 – 3161NucleophileUniRule annotation
    Binding sitei324 – 3241Substrate

    GO - Molecular functioni

    1. beta-galactosidase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. galactose metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseUniRule annotationImported, Hydrolase

    Keywords - Ligandi

    Metal-bindingUniRule annotation, ZincUniRule annotation

    Enzyme and pathway databases

    BioCyciSFLA591167:GI5Y-5026-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
    Short name:
    Beta-galUniRule annotation
    Gene namesi
    Ordered Locus Names:Sfla_4952Imported
    OrganismiStreptomyces pratensis (strain ATCC 33331 / IAF-45CD)Imported
    Taxonomic identifieri591167 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
    ProteomesiUP000002066: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. beta-galactosidase complex Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliE8W331.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 42 family.UniRule annotation

    Phylogenomic databases

    KOiK12308.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    3.40.50.880. 1 hit.
    InterProiIPR013739. Beta_galactosidase_C.
    IPR013738. Beta_galactosidase_Trimer.
    IPR029062. Class_I_gatase-like.
    IPR003476. Glyco_hydro_42.
    IPR013529. Glyco_hydro_42_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF02449. Glyco_hydro_42. 1 hit.
    PF08533. Glyco_hydro_42C. 1 hit.
    PF08532. Glyco_hydro_42M. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001084. B-galactosidase. 1 hit.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF52317. SSF52317. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E8W331-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPHSESAPYP VGLHKLAFGG DYNPEQWPEE VWHEDVRLMR EAGVTMVSVG    50
    IFSWALLEPE PGTYDFGWLD RLLDLLHVNG IRADLGTPTV VPPAWFYRAH 100
    PEALPVSRDG VRYAFGSRGA ICHSSAPYRA AAADITEQLA RRYGNHPALA 150
    MWHVHNEYGV PVSACYCDSC AAHFRRWLAA RHGSADAVNA AWGTAFWGQR 200
    YRSLEDIDPP RTTPTVGNPA QQLDYARFAD ATMRENFTAE RDILHRLAPG 250
    IPVTTNFMTA LSQCESVDYW AWGREVDIVS NDHYLITDGR RTHVNLAMAA 300
    DLTRSVAGGA PWLLLEHSTS GVNWQPRNPA KRPGEMARNS LAHVARGSEG 350
    AMFFQWRQSR RGAEKFHSAM VPHAGTDSRI WREVSALGAG LGLLEGIRGT 400
    RTVADVAMIW DWQSWWAQGL EWRPSEEHDA RERADTFYAS LFDRHLTVDF 450
    AHPDADLSGY PLVVVPALYL ATEETGRNLR RYVEQGGTLV VSYFSGIVDA 500
    DDAVHPGAYP GALRDVLGLT VEEFSPLGEG GTVRLITPEG APEGPELTGD 550
    LWSDVVIPRG AETVWSYADG IPAGRPAVTR NRLGEGTAWY LSTRLSGPDL 600
    DAVLDRAAAD ARIEPRTSLP YDVEVVRRTG DSGSYLFVIN HTDAEAVVAL 650
    DTPGTELLTG EPAVDKLAVP AGAVRVVRLD G 681
    Length:681
    Mass (Da):74,827
    Last modified:April 5, 2011 - v1
    Checksum:iA9C3C0E8F32B7364
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002475 Genomic DNA. Translation: ADW06353.1.
    RefSeqiYP_004925870.1. NC_016114.1.

    Genome annotation databases

    EnsemblBacteriaiADW06353; ADW06353; Sfla_4952.
    GeneIDi11368625.
    KEGGisfa:Sfla_4952.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002475 Genomic DNA. Translation: ADW06353.1 .
    RefSeqi YP_004925870.1. NC_016114.1.

    3D structure databases

    ProteinModelPortali E8W331.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADW06353 ; ADW06353 ; Sfla_4952 .
    GeneIDi 11368625.
    KEGGi sfa:Sfla_4952.

    Phylogenomic databases

    KOi K12308.

    Enzyme and pathway databases

    BioCyci SFLA591167:GI5Y-5026-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    3.40.50.880. 1 hit.
    InterProi IPR013739. Beta_galactosidase_C.
    IPR013738. Beta_galactosidase_Trimer.
    IPR029062. Class_I_gatase-like.
    IPR003476. Glyco_hydro_42.
    IPR013529. Glyco_hydro_42_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF02449. Glyco_hydro_42. 1 hit.
    PF08533. Glyco_hydro_42C. 1 hit.
    PF08532. Glyco_hydro_42M. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001084. B-galactosidase. 1 hit.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF52317. SSF52317. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Streptomyces flavogriseus ATCC 33331."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P., Mead D., Woyke T.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33331 / DSM 40990 / IAF-45CDImported.

    Entry informationi

    Entry nameiE8W331_STRFA
    AccessioniPrimary (citable) accession number: E8W331
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3