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E8W2X6

- E8W2X6_STRFA

UniProt

E8W2X6 - E8W2X6_STRFA

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, Sfla_3770
Organism
Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei135 – 1351 By similarityUniRule annotation
Active sitei567 – 5671 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciSFLA591167:GI5Y-3821-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Sfla_3770Imported
OrganismiStreptomyces pratensis (strain ATCC 33331 / IAF-45CD)Imported
Taxonomic identifieri591167 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000002066: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8W2X6-1 [UniParc]FASTAAdd to Basket

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MSSADQTPAA NTELRADIRR LGDLLGETLV RQEGQDLLDL VERVRALTRE    50
DGEAAAELLG DTDLETAAQL VRAFSTYFHL ANVTEQVHRA HEMRDRRSAE 100
GGLLARTADR LKDADPDHLR ETVKNLNVRP VFTAHPTEAA RRSVLNKLRR 150
IAELLETPVI EADRRRQDIR LAENIDLIWQ TDELRVVRPE PADEARNAIY 200
YLDELHANAV GDVLEDLAAE LERVGVELPA GTRPLTFGTW IGGDRDGNPN 250
VTPTVTWDVL ILQHEHGITD ALELVDQLRG LLSNSIRYTG ATDELLTSLQ 300
TDLERLPEIS PRYKRLNAEE PYRLKATCVR QKLVNTRERL ASGTPHRPGC 350
DYLGTAELIA DLALIQTSLR EHRGGLFADG RMDRTIRTLT AFGLQLATMD 400
VREHADAHHH TLGQLFDRLG EESWRYTDMP RDYRQKLLAK ELRSRRPLAP 450
TPAPLDAAGE KTLGVFHTIS QAFERFGPEV IESYIISMCQ GADDVFAAAV 500
LAREAGLLDL HGGWAKIGIV PLLETTDELK AADVILDEML ADPSYRRLVS 550
LRGDVQEVML GYSDSSKFGG ITTSQWEIHR AQRRLRDVAH RYGVRLRLFH 600
GRGGTVGRGG GPSHDAILAQ PWGTLEGEIK VTEQGEVISD KYLIPALARE 650
NLELTVAATL QASALHTAPR QSDEALARWD AAMDTVSDAA HQAYRKLVED 700
PDLPAYFLAS TPVDQLADLH LGSRPSRRPG SGVSLDGLRA IPWVFGWTQS 750
RQIVPGWFGV GSGLKALREA GLDTVLDEMH EQWHFFQNFL SNVEMTLAKT 800
DLRIARHYVD TLVPDELKHV FDVIQAEHEL TVQEVLKVTG GKELLGTNPV 850
LQQTFAIRDA YLDPISYLQV SLLARQRQAA ERGEEPDPLL ARALLLTVNG 900
VAAGLRNTG 909
Length:909
Mass (Da):101,098
Last modified:April 5, 2011 - v1
Checksum:i7F614AE11F70D53B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002475 Genomic DNA. Translation: ADW05187.1.
RefSeqiYP_004924704.1. NC_016114.1.

Genome annotation databases

EnsemblBacteriaiADW05187; ADW05187; Sfla_3770.
GeneIDi11366453.
KEGGisfa:Sfla_3770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002475 Genomic DNA. Translation: ADW05187.1 .
RefSeqi YP_004924704.1. NC_016114.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADW05187 ; ADW05187 ; Sfla_3770 .
GeneIDi 11366453.
KEGGi sfa:Sfla_3770.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci SFLA591167:GI5Y-3821-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Streptomyces flavogriseus ATCC 33331."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P., Mead D., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33331 / DSM 40990 / IAF-45CD.

Entry informationi

Entry nameiE8W2X6_STRFA
AccessioniPrimary (citable) accession number: E8W2X6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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