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E8W2X6

- E8W2X6_STRFA

UniProt

E8W2X6 - E8W2X6_STRFA

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei135 – 1351UniRule annotation
Active sitei567 – 5671UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSFLA591167:GI5Y-3821-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Sfla_3770Imported
OrganismiStreptomyces pratensis (strain ATCC 33331 / IAF-45CD)Imported
Taxonomic identifieri591167 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000002066: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8W2X6 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSSADQTPAA NTELRADIRR LGDLLGETLV RQEGQDLLDL VERVRALTRE
60 70 80 90 100
DGEAAAELLG DTDLETAAQL VRAFSTYFHL ANVTEQVHRA HEMRDRRSAE
110 120 130 140 150
GGLLARTADR LKDADPDHLR ETVKNLNVRP VFTAHPTEAA RRSVLNKLRR
160 170 180 190 200
IAELLETPVI EADRRRQDIR LAENIDLIWQ TDELRVVRPE PADEARNAIY
210 220 230 240 250
YLDELHANAV GDVLEDLAAE LERVGVELPA GTRPLTFGTW IGGDRDGNPN
260 270 280 290 300
VTPTVTWDVL ILQHEHGITD ALELVDQLRG LLSNSIRYTG ATDELLTSLQ
310 320 330 340 350
TDLERLPEIS PRYKRLNAEE PYRLKATCVR QKLVNTRERL ASGTPHRPGC
360 370 380 390 400
DYLGTAELIA DLALIQTSLR EHRGGLFADG RMDRTIRTLT AFGLQLATMD
410 420 430 440 450
VREHADAHHH TLGQLFDRLG EESWRYTDMP RDYRQKLLAK ELRSRRPLAP
460 470 480 490 500
TPAPLDAAGE KTLGVFHTIS QAFERFGPEV IESYIISMCQ GADDVFAAAV
510 520 530 540 550
LAREAGLLDL HGGWAKIGIV PLLETTDELK AADVILDEML ADPSYRRLVS
560 570 580 590 600
LRGDVQEVML GYSDSSKFGG ITTSQWEIHR AQRRLRDVAH RYGVRLRLFH
610 620 630 640 650
GRGGTVGRGG GPSHDAILAQ PWGTLEGEIK VTEQGEVISD KYLIPALARE
660 670 680 690 700
NLELTVAATL QASALHTAPR QSDEALARWD AAMDTVSDAA HQAYRKLVED
710 720 730 740 750
PDLPAYFLAS TPVDQLADLH LGSRPSRRPG SGVSLDGLRA IPWVFGWTQS
760 770 780 790 800
RQIVPGWFGV GSGLKALREA GLDTVLDEMH EQWHFFQNFL SNVEMTLAKT
810 820 830 840 850
DLRIARHYVD TLVPDELKHV FDVIQAEHEL TVQEVLKVTG GKELLGTNPV
860 870 880 890 900
LQQTFAIRDA YLDPISYLQV SLLARQRQAA ERGEEPDPLL ARALLLTVNG

VAAGLRNTG
Length:909
Mass (Da):101,098
Last modified:April 5, 2011 - v1
Checksum:i7F614AE11F70D53B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002475 Genomic DNA. Translation: ADW05187.1.
RefSeqiYP_004924704.1. NC_016114.1.

Genome annotation databases

EnsemblBacteriaiADW05187; ADW05187; Sfla_3770.
GeneIDi11366453.
KEGGisfa:Sfla_3770.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002475 Genomic DNA. Translation: ADW05187.1 .
RefSeqi YP_004924704.1. NC_016114.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADW05187 ; ADW05187 ; Sfla_3770 .
GeneIDi 11366453.
KEGGi sfa:Sfla_3770.

Phylogenomic databases

KOi K01595.

Enzyme and pathway databases

BioCyci SFLA591167:GI5Y-3821-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Streptomyces flavogriseus ATCC 33331."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P., Mead D., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33331 / DSM 40990 / IAF-45CDImported.

Entry informationi

Entry nameiE8W2X6_STRFA
AccessioniPrimary (citable) accession number: E8W2X6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3