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E8W1I5 (E8W1I5_STRFA) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu HAMAP-Rule MF_00118

Short name=EF-Tu HAMAP-Rule MF_00118
Gene names
Name:tuf HAMAP-Rule MF_00118
Ordered Locus Names:Sfla_2530 EMBL ADW03959.1
OrganismStreptomyces pratensis (strain ATCC 33331 / IAF-45CD) [Complete proteome] [HAMAP] EMBL ADW03959.1
Taxonomic identifier591167 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325 HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325 HAMAP-Rule MF_00118

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding19 – 268GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding83 – 875GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding138 – 1414GTP By similarity HAMAP-Rule MF_00118

Sequences

Sequence LengthMass (Da)Tools
E8W1I5 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 882C0AC6AFFA5073

FASTA39743,734
        10         20         30         40         50         60 
MAKAKFERTK PHVNIGTIGH IDHGKTTLTA AITKVLHDAY PDLNEASAFD QIDKAPEERQ 

        70         80         90        100        110        120 
RGITISIAHV EYQTESRHYA HVDCPGHADY IKNMITGAAQ MDGAILVVAA TDGPMPQTKE 

       130        140        150        160        170        180 
HVLLARQVGV PYIVVALNKA DMVDDEEILE LVELEVRELL SEYEFPGDDL PVVKVSALKA 

       190        200        210        220        230        240 
LEGDAEWGKT VLDLMKAVDE NIPQPERDVE KPFLMPIEDV FTITGRGTVV TGRIERGVLK 

       250        260        270        280        290        300 
VNETVDIVGI KQEKTTTTVT GIEMFRKLLD EGQAGENVGL LLRGIKREDV ERGQVIIKPG 

       310        320        330        340        350        360 
SVTPHTEFQA QAYILSKDEG GRHTPFFNNY RPQFYFRTTD VTGVVTLPEG TEMVMPGDNT 

       370        380        390 
LMDVALIQPV AMEEGLKFAI REGGRTVGAG QVTKIVK 

« Hide

References

[1]"Complete sequence of chromosome of Streptomyces flavogriseus ATCC 33331."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Brumm P., Mead D., Woyke T.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33331 / DSM 40990 / IAF-45CD.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002475 Genomic DNA. Translation: ADW03959.1.
RefSeqYP_004923476.1. NC_016114.1.

3D structure databases

ProteinModelPortalE8W1I5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADW03959; ADW03959; Sfla_2530.
GeneID11368039.
KEGGsfa:Sfla_2530.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02358.

Enzyme and pathway databases

BioCycSFLA591167:GI5Y-2547-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8W1I5_STRFA
AccessionPrimary (citable) accession number: E8W1I5
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)