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E8VNZ5 (E8VNZ5_VIBVM) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Holliday junction ATP-dependent DNA helicase RuvA HAMAP-Rule MF_00031

EC=3.6.4.12 HAMAP-Rule MF_00031
Gene names
Name:ruvA HAMAP-Rule MF_00031
Ordered Locus Names:VVMO6_01026 EMBL ADV86048.1
OrganismVibrio vulnificus (strain MO6-24/O) [Complete proteome] [HAMAP] EMBL ADV86048.1
Taxonomic identifier914127 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length204 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB By similarity. HAMAP-Rule MF_00031 SAAS SAAS011114

Catalytic activity

ATP + H2O = ADP + phosphate. HAMAP-Rule MF_00031 SAAS SAAS011114

Subunit structure

Forms a complex with RuvB By similarity. HAMAP-Rule MF_00031 SAAS SAAS011114

Sequence similarities

Belongs to the RuvA family. HAMAP-Rule MF_00031

Sequences

Sequence LengthMass (Da)Tools
E8VNZ5 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 3256FAECAD1EC08B

FASTA20422,205
        10         20         30         40         50         60 
MIGRLRGILL EKQPPELLIE VNGIGYEVQM PMSCFYELPN IGEEAIIYTH FVVREDAQLL 

        70         80         90        100        110        120 
YGFNTVKERA LFREVIKANG VGPKLGLAIL SGMTASQFVA SVEREDISTL VKLPGVGKKT 

       130        140        150        160        170        180 
AERLVVEMKD RLKGWSAGDL FTPFTDAAPV DSGSTSSNSA EEEAVSALLA LGYKPVQASK 

       190        200 
VVSQIAKPDM TSEQLIREAL KSMV 

« Hide

References

[1]"Complete genome sequence of Vibrio vulnificus MO6-24/O."
Park J.H., Cho Y.J., Chun J., Seok Y.J., Lee J.K., Kim K.S., Lee K.H., Park S.J., Choi S.H.
J. Bacteriol. 193:2062-2063(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MO6-24/O EMBL ADV86048.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002469 Genomic DNA. Translation: ADV86048.1.
RefSeqYP_004188251.1. NC_014965.1.

3D structure databases

ProteinModelPortalE8VNZ5.
SMRE8VNZ5. Positions 1-202.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADV86048; ADV86048; VVMO6_01026.
GeneID10165794.
KEGGvvm:VVMO6_01026.
PATRIC47050077. VBIVibVul176069_1024.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK03550.

Enzyme and pathway databases

BioCycVVUL914127:GJJH-1099-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00031. DNA_helic_RuvA.
InterProIPR011114. DNA_helicas_Holl-junc_RuvA_C.
IPR013849. DNA_helicase_Holl-junc_RuvA_I.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR012340. NA-bd_OB-fold.
IPR000085. RuvA.
IPR010994. RuvA_2-like.
[Graphical view]
PfamPF07499. RuvA_C. 1 hit.
PF01330. RuvA_N. 1 hit.
[Graphical view]
SMARTSM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMSSF46929. SSF46929. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00084. ruvA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE8VNZ5_VIBVM
AccessionPrimary (citable) accession number: E8VNZ5
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 16, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)