E8VNZ5 (E8VNZ5_VIBVM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Holliday junction ATP-dependent DNA helicase RuvA HAMAP-Rule MF_00031
EC=3.6.4.12 HAMAP-Rule MF_00031

Gene names

Name:	ruvA HAMAP-Rule MF_00031
Ordered Locus Names:	VVMO6_01026 EMBL ADV86048.1

Organism

Vibrio vulnificus (strain MO6-24/O) [Complete proteome] [HAMAP]

Taxonomic identifier

914127 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › Vibrio vulnificus

Protein attributes

Sequence length	204 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB By similarity. HAMAP-Rule MF_00031 SAAS SAAS011114
Catalytic activity	ATP + H2O = ADP + phosphate. HAMAP-Rule MF_00031 SAAS SAAS011114
Subunit structure	Forms a complex with RuvB By similarity. HAMAP-Rule MF_00031
Sequence similarities	Belongs to the RuvA family. HAMAP-Rule MF_00031

Ontologies

Keywords
Biological process	DNA damage DNA recombination HAMAP-Rule MF_00031 SAAS SAAS011114 DNA repair SOS response HAMAP-Rule MF_00031 SAAS SAAS011114
Ligand	ATP-binding DNA-binding HAMAP-Rule MF_00031 SAAS SAAS011114 Nucleotide-binding
Molecular function	Helicase HAMAP-Rule MF_00031 SAAS SAAS011114 EMBL ADV86048.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA duplex unwinding Inferred from electronic annotation. Source: GOC DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repair Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular_component	Holliday junction helicase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: UniProtKB-KW four-way junction helicase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E8VNZ5 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 3256FAECAD1EC08B	FASTA	204	22,205
	10 20 30 40 50 60 MIGRLRGILL EKQPPELLIE VNGIGYEVQM PMSCFYELPN IGEEAIIYTH FVVREDAQLL 70 80 90 100 110 120 YGFNTVKERA LFREVIKANG VGPKLGLAIL SGMTASQFVA SVEREDISTL VKLPGVGKKT 130 140 150 160 170 180 AERLVVEMKD RLKGWSAGDL FTPFTDAAPV DSGSTSSNSA EEEAVSALLA LGYKPVQASK 190 200 VVSQIAKPDM TSEQLIREAL KSMV

References

[1]	"Complete genome sequence of Vibrio vulnificus MO6-24/O." Park J.H., Cho Y.J., Chun J., Seok Y.J., Lee J.K., Kim K.S., Lee K.H., Park S.J., Choi S.H. J. Bacteriol. 193:2062-2063(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MO6-24/O.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002469 Genomic DNA. Translation: ADV86048.1.
RefSeq	YP_004188251.1. NC_014965.1.
3D structure databases
ProteinModelPortal	E8VNZ5.
SMR	E8VNZ5. Positions 1-202.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADV86048; ADV86048; VVMO6_01026.
GeneID	10165794.
KEGG	vvm:VVMO6_01026.
PATRIC	47050077. VBIVibVul176069_1024.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K03550.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
HAMAP	MF_00031. DNA_helic_RuvA.
InterPro	IPR011114. DNA_helicas_Holl-junc_RuvA_C. IPR013849. DNA_helicase_Holl-junc_RuvA_I. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. IPR012340. NA-bd_OB-fold. IPR000085. RuvA. IPR010994. RuvA_2-like. [Graphical view]
Pfam	PF07499. RuvA_C. 1 hit. PF01330. RuvA_N. 1 hit. [Graphical view]
SMART	SM00278. HhH1. 2 hits. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF47781. RuvA_2_like. 1 hit. SSF46929. RuvA_C-like. 1 hit.
TIGRFAMs	TIGR00084. ruvA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E8VNZ5_VIBVM

Accession

Primary (citable) accession number: E8VNZ5

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	April 3, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)