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Protein
Submitted name:

2-oxoglutarate dehydrogenase E1 component

Gene

VVMO6_02195

Organism
Vibrio vulnificus (strain MO6-24/O)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciVVUL914127:GJJH-2281-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase E1 componentImported (EC:1.2.4.2Imported)
Gene namesi
Ordered Locus Names:VVMO6_02195Imported
OrganismiVibrio vulnificus (strain MO6-24/O)Imported
Taxonomic identifieri914127 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000006905: Chromosome I

Structurei

3D structure databases

ProteinModelPortaliE8VNP7.
SMRiE8VNP7. Positions 85-935.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK00164.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

E8VNP7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHNGVMKAWL ESSHLAGANA TYVEDLYELY LSDPDLVSEE WKRVFEGLPK
60 70 80 90 100
PTKEVAEQPH SRVRDYFRRL AQETKHYSVQ VSDPDVDAKQ VKVLQLINAY
110 120 130 140 150
RFRGHEAAEL DPLGLWQRPT VAELDPAFHN LTEDDFEETF NVGSFAVGQE
160 170 180 190 200
TMPLKDIYTA LKKTYCGSIG AEYMHMTDTE QKRWIQQRLE SVVGQPSFDK
210 220 230 240 250
DEKRTFLAEL TAAEGLERYL GAKFPGAKRF SLEGGDAMIP MMKELIRHAG
260 270 280 290 300
RSGMREVVIG MAHRGRLNML VNVLGKKPQD LFDEFAGKHG ESWGTGDVKY
310 320 330 340 350
HQGFSADFAT PGGDVHLALA FNPSHLEIVN PVVMGSVRAR QDRLGDDDGS
360 370 380 390 400
KVLPITIHGD SAIAGQGVVA ETFNMSQARG FCVGGTVRVV VNNQVGFTTS
410 420 430 440 450
NPRDTRSTMY CTDIAKMVQA PIFHVNADDP EAVAFVTRIA LDYRNEFKRD
460 470 480 490 500
VVIDLVCYRR HGHNEADEPN ATQPLMYQKI KKHPTPRKLY ADVLIDRNEC
510 520 530 540 550
DIETATQMVN EYRDALDHGE VVVKEWRPMA LHSVDWSPYL GHDWDTPWSN
560 570 580 590 600
TYDKQRLVEL GKRLCQYPES HTLHSRVSKL YNDRTAMTNG EKELDWGMAE
610 620 630 640 650
TLAYATLVDD GKRIRISGQD SGRGTFFHRH AVLHNQNDAS TYVPLANIHD
660 670 680 690 700
KQGPFEVFDS VLSEEAVLAF EYGYATAEPS GLTLWEAQFG DFANGAQVVI
710 720 730 740 750
DQFISSGEQK WARLCGLTML LPHGYEGQGP EHSSARLERY LQLCAEQNMQ
760 770 780 790 800
VVVPSTPAQV YHMIRRQVVR PMRRPLIVMS PKSLLRHPLC TSSLDDLANG
810 820 830 840 850
TFMPAIPEID ELDPAKVKRV VFCSGKVYFD LLEQRRNNEQ DDVAIVRIEQ
860 870 880 890 900
LYPFPMDDVK AAIAPYVNVE DFVWCQEEPQ NQGAWYCSQH NFRAAIPAGT
910 920 930 940
ELKYAGRPAS ASPAVGYMSV HLKQQKALID DALNVNEKTS D
Length:941
Mass (Da):106,008
Last modified:April 5, 2011 - v1
Checksum:iB36F7B589608A3DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002469 Genomic DNA. Translation: ADV87217.1.
RefSeqiWP_011149792.1. NC_014965.1.
YP_004189420.1. NC_014965.1.

Genome annotation databases

EnsemblBacteriaiADV87217; ADV87217; VVMO6_02195.
GeneIDi10166976.
KEGGivvm:VVMO6_02195.
PATRICi47052420. VBIVibVul176069_2174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002469 Genomic DNA. Translation: ADV87217.1.
RefSeqiWP_011149792.1. NC_014965.1.
YP_004189420.1. NC_014965.1.

3D structure databases

ProteinModelPortaliE8VNP7.
SMRiE8VNP7. Positions 85-935.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADV87217; ADV87217; VVMO6_02195.
GeneIDi10166976.
KEGGivvm:VVMO6_02195.
PATRICi47052420. VBIVibVul176069_2174.

Phylogenomic databases

KOiK00164.

Enzyme and pathway databases

BioCyciVVUL914127:GJJH-2281-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MO6-24/OImported.

Entry informationi

Entry nameiE8VNP7_VIBVM
AccessioniPrimary (citable) accession number: E8VNP7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.