E8VKI4 (E8VKI4_BACST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-dehydropantoate 2-reductase RuleBase RU003776
EC=1.1.1.169 RuleBase RU003776

Gene names

Ordered Locus Names:

BSn5_19290

Organism

Bacillus subtilis (strain BSn5) [Complete proteome] [HAMAP]

Taxonomic identifier

936156 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus subtilis group › Bacillus subtilis

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid By similarity. RuleBase RU003776
Catalytic activity	(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH. RuleBase RU003776
Sequence similarities	Belongs to the ketopantoate reductase family. RuleBase RU003776

Ontologies

Keywords
Biological process	Pantothenate biosynthesis RuleBase RU003776
Ligand	NADP RuleBase RU003776
Molecular function	Oxidoreductase RuleBase RU003776 EMBL ADV96462.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pantothenate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	2-dehydropantoate 2-reductase activity Inferred from electronic annotation. Source: EC NADP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E8VKI4 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 9D70717BB57681E4	FASTA	303	33,616
	10 20 30 40 50 60 MKFLVVGAGG VGGYIGGRLS EKGNDVTFLV RQKRAEQLKK TGLVIHSEKG NVSFQPELIS 70 80 90 100 110 120 AGETGQFDVV IIASKAYSLG QVIEDVKPFI HQESVIIPFL NGYRHYEQLF AAFSKEQVLG 130 140 150 160 170 180 GLCFIESALD NKGEIHHTST SHRFVFGEWN GERTERIRAL EEAFSGVKAE VIISGHIEKD 190 200 210 220 230 240 IWKKYLFIAA QAGITTLFQR PLGPILATEA GRHTAQTLIG EICAVLRKEG VPADPDLEEE 250 260 270 280 290 300 SFRTMTSMSY HMKSSMLRDM ENGQTTEGDH LHGFLLEKAK RLSLAAPVLE TVYANLQMYE AEK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Bacillus subtilis BSn5, an endophytic bacterium of Amorphophallus konjac with antimicrobial activity to plant pathogen Erwinia carotovora subsp. carotovora." Deng Y., Zhu Y., Wang P., Zhu L., Zheng J., Li R., Ruan L., Peng D., Sun M. J. Bacteriol. 193:2070-2071(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BSn5.
[2]	"Complete Genome Sequence of Bacillus Subtilis BSn5, a Strain of Plant-associated Bacterium with Antimicrobial Activity to Soil-borne Plant Pathogens." Deng Y., Sun M. Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BSn5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002468 Genomic DNA. Translation: ADV96462.1.
RefSeq	YP_004207489.1. NC_014976.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADV96462; ADV96462; BSn5_19290.
GeneID	10184586.
KEGG	bsn:BSn5_19290.
PATRIC	46875207. VBIBacSub180317_3939.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000050222.
KO	K00077.
Enzyme and pathway databases
BioCyc	BSUB936156:GHCY-3939-MONOMER.
Family and domain databases
Gene3D	1.10.1040.10. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR003710. ApbA. IPR013752. ApbA_C. IPR013332. ApbA_N. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF02558. ApbA. 1 hit. PF08546. ApbA_C. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR00745. apbA_panE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E8VKI4_BACST

Accession

Primary (citable) accession number: E8VKI4

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)