E8VAI5 (E8VAI5_BACST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Succinyl-CoA ligase [ADP-forming] subunit alpha RuleBase RU000699
EC=6.2.1.5 RuleBase RU000699

Gene names

Ordered Locus Names:

BSn5_20160 EMBL ADV96636.1

Organism

Bacillus subtilis (strain BSn5) [Complete proteome] [HAMAP] EMBL ADV96636.1

Taxonomic identifier

936156 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus subtilis group › Bacillus subtilis

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. RuleBase RU000699
Subunit structure	Heterotetramer of two alpha and two beta subunits By similarity. RuleBase RU000699
Sequence similarities	Belongs to the succinate/malate CoA ligase alpha subunit family. RuleBase RU000677

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000699 Nucleotide-binding
Molecular function	Ligase RuleBase RU000677 EMBL ADV96636.1
PTM	Phosphoprotein RuleBase RU000677
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP citrate synthase activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro succinate-CoA ligase (ADP-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	247	1	Tele-phosphohistidine intermediate By similarity PIRSR PIRSR001553-1

Sequences

	Sequence		Length	Mass (Da)
	E8VAI5 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: EE0462D35F2B9978	FASTA	300	31,382
	10 20 30 40 50 60 MSVFINKDTR VIVQGITGST ALFHTKQMLE YGTNIVGGVT PGKGGTEAEG VPVFNTVAEA 70 80 90 100 110 120 VQTTGANASV IYVPAPFAAD AIMEAVDAEL DLVICITEHI PVLDMVKVKR FMEGKKTRLI 130 140 150 160 170 180 GPNCPGVITP EECKIGIMPG YIHKKGHVGV VSRSGTLTYE AVHQLSEAGV GQSTAVGIGG 190 200 210 220 230 240 DPVNGTNFID VLKAFNEDPD THAVIMIGEI GGTAEEEAAE WVKANMTKPV VGFIGGKTAP 250 260 270 280 290 300 PGKRMGHAGA IISGGKGTAD EKIKTLNACG IEVAETPSVM GETLIKVLKE KNLFETCKTH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Bacillus subtilis BSn5, an endophytic bacterium of Amorphophallus konjac with antimicrobial activity for the plant pathogen Erwinia carotovora subsp. carotovora." Deng Y., Zhu Y., Wang P., Zhu L., Zheng J., Li R., Ruan L., Peng D., Sun M. J. Bacteriol. 193:2070-2071(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BSn5 EMBL ADV96636.1.
[2]	"Complete Genome Sequence of Bacillus Subtilis BSn5, a Strain of Plant-associated Bacterium with Antimicrobial Activity to Soil-borne Plant Pathogens." Deng Y., Sun M. Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: BSn5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002468 Genomic DNA. Translation: ADV96636.1.
RefSeq	YP_004207663.1. NC_014976.1.
3D structure databases
ProteinModelPortal	E8VAI5.
SMR	E8VAI5. Positions 2-288.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADV96636; ADV96636; BSn5_20160.
GeneID	10184760.
KEGG	bsn:BSn5_20160.
PATRIC	46875556. VBIBacSub180317_4112.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000239685.
KO	K01902.
Enzyme and pathway databases
BioCyc	BSUB936156:GHCY-4112-MONOMER.
Family and domain databases
Gene3D	3.40.50.261. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR017440. Cit_synth/succinyl-CoA_lig_AS. IPR003781. CoA-bd. IPR005810. CoA_lig_alpha. IPR005811. CoA_ligase. IPR016040. NAD(P)-bd_dom. IPR016102. Succinyl-CoA_synth-like. [Graphical view]
Pfam	PF02629. CoA_binding. 1 hit. PF00549. Ligase_CoA. 1 hit. [Graphical view]
PIRSF	PIRSF001553. SucCS_alpha. 1 hit.
PRINTS	PR01798. SCOASYNTHASE.
SMART	SM00881. CoA_binding. 1 hit. [Graphical view]
SUPFAM	SSF52210. CoA_ligase. 1 hit.
TIGRFAMs	TIGR01019. sucCoAalpha. 1 hit.
PROSITE	PS01216. SUCCINYL_COA_LIG_1. 1 hit. PS00399. SUCCINYL_COA_LIG_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E8VAI5_BACST

Accession

Primary (citable) accession number: E8VAI5

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 29, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)