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E8V8U3

- E8V8U3_TERSS

UniProt

E8V8U3 - E8V8U3_TERSS

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Protein
Inorganic pyrophosphatase
Gene
ppa, AciPR4_3376
Organism
Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi66 – 661Magnesium 1 By similarityUniRule annotation
Metal bindingi71 – 711Magnesium 1 By similarityUniRule annotation
Metal bindingi71 – 711Magnesium 2 By similarityUniRule annotation
Metal bindingi103 – 1031Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. inorganic diphosphatase activity Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. phosphate-containing compound metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTSAA401053:GHYY-3418-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Inorganic pyrophosphataseUniRule annotation (EC:3.6.1.1UniRule annotation)
Alternative name(s):
Pyrophosphate phospho-hydrolase
Gene namesi
Name:ppaUniRule annotation
Ordered Locus Names:AciPR4_3376Imported
OrganismiTerriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4)Imported
Taxonomic identifieri401053 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeTerriglobus
ProteomesiUP000006844: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PPase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000236472.
KOiK01507.

Family and domain databases

Gene3Di3.90.80.10. 1 hit.
HAMAPiMF_00209. Inorganic_PPase.
InterProiIPR008162. Pyrophosphatase.
[Graphical view]
PANTHERiPTHR10286. PTHR10286. 1 hit.
PfamiPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMiSSF50324. SSF50324. 1 hit.
PROSITEiPS00387. PPASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8V8U3-1 [UniParc]FASTAAdd to Basket

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MPNYLELPVG SKAPHEVNVV IEIPLDGVTK FEYDKQLHVF RLDRNLYSPV    50
HYPGDYGFIP STLGDDGDPL DVLVLVDTPS FPGCVQSVRP IGLMEMIDNG 100
EGDEKVLAVG CANPRYFDVN SYEQIHPHKL KEIIHFFSTY KDLEGKKVEI 150
KGWRDTAYAH EVIKKSMAAF KNGTKI 176
Length:176
Mass (Da):19,837
Last modified:April 5, 2011 - v1
Checksum:iD88858073830F3F3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002467 Genomic DNA. Translation: ADV84130.1.
RefSeqiYP_004184124.1. NC_014963.1.

Genome annotation databases

EnsemblBacteriaiADV84130; ADV84130; AciPR4_3376.
GeneIDi10161308.
KEGGitsa:AciPR4_3376.
PATRICi46832646. VBITerSaa54836_3502.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002467 Genomic DNA. Translation: ADV84130.1 .
RefSeqi YP_004184124.1. NC_014963.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADV84130 ; ADV84130 ; AciPR4_3376 .
GeneIDi 10161308.
KEGGi tsa:AciPR4_3376.
PATRICi 46832646. VBITerSaa54836_3502.

Phylogenomic databases

HOGENOMi HOG000236472.
KOi K01507.

Enzyme and pathway databases

BioCyci TSAA401053:GHYY-3418-MONOMER.

Family and domain databases

Gene3Di 3.90.80.10. 1 hit.
HAMAPi MF_00209. Inorganic_PPase.
InterProi IPR008162. Pyrophosphatase.
[Graphical view ]
PANTHERi PTHR10286. PTHR10286. 1 hit.
Pfami PF00719. Pyrophosphatase. 1 hit.
[Graphical view ]
SUPFAMi SSF50324. SSF50324. 1 hit.
PROSITEi PS00387. PPASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Terriglobus saanensis type strain SP1PR4(T), an Acidobacteria from tundra soil."
    Rawat S.R., Mannisto M.K., Starovoytov V., Goodwin L., Nolan M., Hauser L., Land M., Davenport K.W., Woyke T., Haggblom M.M.
    Stand. Genomic Sci. 7:59-69(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC BAA-1853 / DSM 23119 / SP1PR4.

Entry informationi

Entry nameiE8V8U3_TERSS
AccessioniPrimary (citable) accession number: E8V8U3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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