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Protein

DNA ligase

Gene

AciPR4_3963

Organism
Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTSAA401053:GHYY-4018-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:AciPR4_3963Imported
OrganismiTerriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4)Imported
Taxonomic identifieri401053 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaAcidobacterialesAcidobacteriaceaeTerriglobus
ProteomesiUP000006844 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE8V3M5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK10747.
OMAiIASISHA.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8V3M5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALFLQLAEL ADVLAATSSR LKKRAAIAEG ITAVHAQSPE EAGLFALYLA
60 70 80 90 100
GQTFPEADPR KLNAGGAVLS RIIASISHAA DTAMTEAYRR HGDLGAATHD
110 120 130 140 150
LFLDAGHNPP PTLTFTDLHD AFAQASIART TVIRQIVLTD LLTRAIPVEA
160 170 180 190 200
KYLIKLMLGD MRIGVKQSLV EEAIAVAAEA SLSDVRNAVM LQADLACATE
210 220 230 240 250
MAFAKTLREA RMRLFHPLGF MLASPVETPE EAVERFAKIP VESDASTPPP
260 270 280 290 300
THVEPDPPSV SEDAYTVTAQ EEISPEAIHI HAQIEDKYDG MRVQLHCGDP
310 320 330 340 350
AQPGRVALYS RNREDVTESY PEIAEAFAHA ESGAMILDGE LLAWDVQQER
360 370 380 390 400
ALPFAVLSPR IGRKRVSNEV RTATPVVFMA FDVLYASDSL LLDLPLRERR
410 420 430 440 450
NRLEAIAERL LAVTHSPLAL PATADTGLFA HDNGAAQTGV QRLLLSPISL
460 470 480 490 500
AYSAEDLDRA YNAARERGNE GVMIKAADSI YQPGRRGISW VKLKRQLGTL
510 520 530 540 550
DVVITGAEYG HGKRSQFLSD YTFAIRAPEG DLLNVGKAYS GVTDAEIVKL
560 570 580 590 600
TAWLKDHTLE DQGHFRTVEP GIVLEVAFNN VMRSSRHASG FALRFPRILR
610 620 630
IRTDKPLEEI DTLERVEEIY QSQPDKPAEA
Length:630
Mass (Da):68,879
Last modified:April 5, 2011 - v1
Checksum:i6931CDA56D387B40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002467 Genomic DNA. Translation: ADV84712.1.
RefSeqiYP_004184706.1. NC_014963.1.

Genome annotation databases

EnsemblBacteriaiADV84712; ADV84712; AciPR4_3963.
KEGGitsa:AciPR4_3963.
PATRICi46833881. VBITerSaa54836_4105.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002467 Genomic DNA. Translation: ADV84712.1.
RefSeqiYP_004184706.1. NC_014963.1.

3D structure databases

ProteinModelPortaliE8V3M5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADV84712; ADV84712; AciPR4_3963.
KEGGitsa:AciPR4_3963.
PATRICi46833881. VBITerSaa54836_4105.

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK10747.
OMAiIASISHA.

Enzyme and pathway databases

BioCyciTSAA401053:GHYY-4018-MONOMER.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Terriglobus saanensis type strain SP1PR4(T), an Acidobacteria from tundra soil."
    Rawat S.R., Mannisto M.K., Starovoytov V., Goodwin L., Nolan M., Hauser L., Land M., Davenport K.W., Woyke T., Haggblom M.M.
    Stand. Genomic Sci. 7:59-69(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC BAA-1853 / DSM 23119 / SP1PR4Imported.

Entry informationi

Entry nameiE8V3M5_TERSS
AccessioniPrimary (citable) accession number: E8V3M5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 1, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.