Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

Thebr_0815

Organism
Thermoanaerobacter brockii subsp. finnii (strain ATCC 43586 / DSM 3389 / AKO-1) (Thermoanaerobacter finnii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:Thebr_0815Imported
OrganismiThermoanaerobacter brockii subsp. finnii (strain ATCC 43586 / DSM 3389 / AKO-1) (Thermoanaerobacter finnii)Imported
Taxonomic identifieri509193 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacteraceaeThermoanaerobacter
Proteomesi
  • UP000002062 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE8UR06
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 77Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini95 – 132Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili264 – 291Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, LipoylUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000281566
KOiK00627

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR003016 2-oxoA_DH_lipoyl-BS
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS00189 LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

E8UR06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVNVVMPKL GLTMKEGRVD RWLKKVGDIV KKGEEIVEVS TDKITNVVES
60 70 80 90 100
PADGILAKIL VNEGEIVPVA TPIGIITAEG EKLEEVEKSE EKFIKATPVA
110 120 130 140 150
KRLAKENNID LSLITGTGPG GRITEEDVKK FISEQKVKTE EEGPKKEVAV
160 170 180 190 200
IEGQALEKVE RMPMDNIRKT ISQRMKKSWS EIPHVTEDIK VDVTELVNLR
210 220 230 240 250
ENLNHISDNK FTYTDLIAKA CVIAIKKNPV VNWSIEGEYI IKNSSINLGI
260 270 280 290 300
AVALDNGLIV PVVKEADKKS LLELSKNIKE LSERARNNKL TPDEIIGSTF
310 320 330 340 350
TITNLGMYEI DSFTPIINPP ESAILGVNKI YKEPVVLDDN IVIRHIIKLS
360 370 380
LSFDHRLIDG ATAAKFLLDL KKTLENPLSL LI
Length:382
Mass (Da):42,392
Last modified:April 5, 2011 - v1
Checksum:iD64F17E577CE7B3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002466 Genomic DNA Translation: ADV79403.1
RefSeqiWP_004401863.1, NC_014964.1

Genome annotation databases

EnsemblBacteriaiADV79403; ADV79403; Thebr_0815
KEGGitbo:Thebr_0815

Similar proteinsi

Entry informationi

Entry nameiE8UR06_THEBF
AccessioniPrimary (citable) accession number: E8UR06
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health