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E8UEB1

- E8UEB1_TAYEM

UniProt

E8UEB1 - E8UEB1_TAYEM

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Protein

Alanine racemase

Gene

TEQUI_1568

Organism
Taylorella equigenitalis (strain MCE9)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei74 – 741Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei173 – 1731SubstrateUniRule annotation
Active sitei300 – 3001Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei348 – 3481Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciTEQU937774:GHXS-1568-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:TEQUI_1568Imported
OrganismiTaylorella equigenitalis (strain MCE9)Imported
Taxonomic identifieri937774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeTaylorella
ProteomesiUP000007472: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei74 – 741N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE8UEB1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279190.
KOiK01775.
OMAiHVANSYI.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8UEB1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKYPLKSLTI VIASLFAAQS NSAPVLSTDD VKVSQLSELS ANAWIEVDVQ
60 70 80 90 100
AFENNIAELQ KLLNGKSKVC AILKADAYGH GINLLMPSII KMNVPCIGIA
110 120 130 140 150
SNEEARIARA HNYEGTIMRV RAASINEIKD GLKYDMEELV GDVTQAQTIN
160 170 180 190 200
ALAKEAGKDV RIHISLNSAG MDRNGIDMST DNGRAEALEL TKFSNLKVVG
210 220 230 240 250
IMTHYPEENE EIIRKDLVRF NEDSKWLIEN AGLNRNQIVI HTANSYTTLT
260 270 280 290 300
VPEAHFDMVR PGGLLYGDSI PTRTEYKRIL SFKSRVANIN HYPKGSTVGY
310 320 330 340 350
DRTFKLERDS MLANLPFGYS DGYRRIFSNK GYVLINGHKV PVVGRVSMNT
360 370 380 390 400
TMVDVTDFPD ILEGAEVVIF GTQGDAKVEQ ADIEEINGAL LADLYTVWGN
410
SNPRIAKPTT TN
Length:412
Mass (Da):45,487
Last modified:April 5, 2011 - v1
Checksum:i7338E2A688B3FC65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002456 Genomic DNA. Translation: ADU92480.1.
RefSeqiYP_004130623.1. NC_014914.1.

Genome annotation databases

EnsemblBacteriaiADU92480; ADU92480; TEQUI_1568.
GeneIDi10115403.
KEGGiteq:TEQUI_1568.
PATRICi45377042. VBITayEqu178523_1512.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002456 Genomic DNA. Translation: ADU92480.1 .
RefSeqi YP_004130623.1. NC_014914.1.

3D structure databases

ProteinModelPortali E8UEB1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADU92480 ; ADU92480 ; TEQUI_1568 .
GeneIDi 10115403.
KEGGi teq:TEQUI_1568.
PATRICi 45377042. VBITayEqu178523_1512.

Phylogenomic databases

HOGENOMi HOG000279190.
KOi K01775.
OMAi HVANSYI.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci TEQU937774:GHXS-1568-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Taylorella equigenitalis MCE9, the causative agent of contagious equine metritis."
    Hebert L., Moumen B., Duquesne F., Breuil M.F., Laugier C., Batto J.M., Renault P., Petry S.
    J. Bacteriol. 193:1785-1785(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MCE9Imported.

Entry informationi

Entry nameiE8UEB1_TAYEM
AccessioniPrimary (citable) accession number: E8UEB1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 26, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3