Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alanine racemase

Gene

TEQUI_1568

Organism
Taylorella equigenitalis (strain MCE9)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (TEQUI_1325), Alanine racemase (TEQUI_1568)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei74Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei173SubstrateUniRule annotation1
Active sitei300Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei348Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciTEQU937774:GHXS-1568-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:TEQUI_1568Imported
OrganismiTaylorella equigenitalis (strain MCE9)Imported
Taxonomic identifieri937774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeTaylorella
Proteomesi
  • UP000007472 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500323248124 – 412Alanine racemaseSequence analysisAdd BLAST389

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei74N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi937774.TEQUI_1568.

Structurei

3D structure databases

ProteinModelPortaliE8UEB1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini279 – 407Ala_racemase_CInterPro annotationAdd BLAST129

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105CJ4. Bacteria.
COG0787. LUCA.
HOGENOMiHOG000279190.
KOiK01775.
OMAiYSDGYRR.
OrthoDBiPOG091H022F.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase. 1 hit.
InterProiView protein in InterPro
IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
PfamiView protein in Pfam
PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
PRINTSiPR00992. ALARACEMASE.
SMARTiView protein in SMART
SM01005. Ala_racemase_C. 1 hit.
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiView protein in PROSITE
PS00395. ALANINE_RACEMASE. 1 hit.

Sequencei

Sequence statusi: Complete.

E8UEB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYPLKSLTI VIASLFAAQS NSAPVLSTDD VKVSQLSELS ANAWIEVDVQ
60 70 80 90 100
AFENNIAELQ KLLNGKSKVC AILKADAYGH GINLLMPSII KMNVPCIGIA
110 120 130 140 150
SNEEARIARA HNYEGTIMRV RAASINEIKD GLKYDMEELV GDVTQAQTIN
160 170 180 190 200
ALAKEAGKDV RIHISLNSAG MDRNGIDMST DNGRAEALEL TKFSNLKVVG
210 220 230 240 250
IMTHYPEENE EIIRKDLVRF NEDSKWLIEN AGLNRNQIVI HTANSYTTLT
260 270 280 290 300
VPEAHFDMVR PGGLLYGDSI PTRTEYKRIL SFKSRVANIN HYPKGSTVGY
310 320 330 340 350
DRTFKLERDS MLANLPFGYS DGYRRIFSNK GYVLINGHKV PVVGRVSMNT
360 370 380 390 400
TMVDVTDFPD ILEGAEVVIF GTQGDAKVEQ ADIEEINGAL LADLYTVWGN
410
SNPRIAKPTT TN
Length:412
Mass (Da):45,487
Last modified:April 5, 2011 - v1
Checksum:i7338E2A688B3FC65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002456 Genomic DNA. Translation: ADU92480.1.
RefSeqiWP_013522715.1. NC_014914.1.

Genome annotation databases

EnsemblBacteriaiADU92480; ADU92480; TEQUI_1568.
KEGGiteq:TEQUI_1568.

Similar proteinsi

Entry informationi

Entry nameiE8UEB1_TAYEM
AccessioniPrimary (citable) accession number: E8UEB1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 27, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported