ID   E8U9H7_DEIML            Unreviewed;       826 AA.
AC   E8U9H7;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN   OrderedLocusNames=Deima_2073 {ECO:0000313|EMBL:ADV67716.1};
OS   Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 /
OS   LB-34).
OC   Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=709986 {ECO:0000313|EMBL:ADV67716.1, ECO:0000313|Proteomes:UP000008635};
RN   [1] {ECO:0000313|EMBL:ADV67716.1, ECO:0000313|Proteomes:UP000008635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34
RC   {ECO:0000313|Proteomes:UP000008635};
RX   PubMed=21677853; DOI=10.4056/sigs.1633949;
RA   Pukall R., Zeytun A., Lucas S., Lapidus A., Hammon N., Deshpande S.,
RA   Nolan M., Cheng J.F., Pitluck S., Liolios K., Pagani I., Mikhailova N.,
RA   Ivanova N., Mavromatis K., Pati A., Tapia R., Han C., Goodwin L., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Brambilla E.M., Rohde M., Goker M., Detter J.C., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Deinococcus maricopensis type strain (LB-
RT   34).";
RL   Stand. Genomic Sci. 4:163-172(2011).
RN   [2] {ECO:0000313|Proteomes:UP000008635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34
RC   {ECO:0000313|Proteomes:UP000008635};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Goodwin L., Pitluck S., Kyrpides N.,
RA   Mavromatis K., Pagani I., Ivanova N., Ovchinnikova G., Zeytun A.,
RA   Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Pukall R., Gehrich-Schroeter G.,
RA   Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Deinococcus maricopensis DSM 21211.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC       ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC         Rule:MF_00595};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946, ECO:0000256|HAMAP-
CC         Rule:MF_00595};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
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DR   EMBL; CP002454; ADV67716.1; -; Genomic_DNA.
DR   RefSeq; WP_013557221.1; NC_014958.1.
DR   AlphaFoldDB; E8U9H7; -.
DR   STRING; 709986.Deima_2073; -.
DR   KEGG; dmr:Deima_2073; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_0; -.
DR   OrthoDB; 9768133at2; -.
DR   Proteomes; UP000008635; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW   Rule:MF_00595};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW   Pyruvate {ECO:0000313|EMBL:ADV67716.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008635}.
FT   ACT_SITE        131
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT                   ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        503
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT                   ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   826 AA;  91101 MW;  429DB5B7E2F1AC22 CRC64;
     MGIREDVNTL GRALGQVLKE QEGEAFFDTV ERVRALVRQA RAGDGDAPLR ELLEGATPED
     AENLVRAFSL YFQLVNLAEE YERVRTLAGR EGVRPQSLEA ALTELHASGL SADDAEALIQ
     RVNLGLTFTA HPTEMRRRTV RAHLVQVARD IPDLSDPTTY DAAVERITAH VEALWNTPEL
     RRLKPTVLDE VKGGLSYVPS IAQAVTRLQR DLQRAFERVY GRPTSARVPL SLHSWMGGDR
     DGNPFVTPDA TRDTLTLHRD RARDLLLNAI RQTYADLSQD ERGEETYRAE LQALHDAVQA
     GQHVDLTAQL DALDARLREH GQARSADVLL APLRTHARTF GQHLVSLDIR EHSALTGAAA
     AALLDAAGMP GYADLPEHAK TELLTRELRS RRPLWPAGEA LPEELERAVG PIREVARAVR
     KVGPRAFGRY IISMSESVSD VLEPLLLARE VGFRVLPVPL FETLDDLERA PSVVWELLSL
     PEYRAVLGSD VQEIMLGYSD SNKDAGFLAA NWALHEAQRR LADVCRRAGV PWRFFHGRGT
     SIGRGGGPAS RAILGQPAGT IGSGLRITEQ GEALADKYSH PVLAHRNLEQ ALSGLLLAAA
     RPAADLPAAW TEALDRAARA SAGAYRALVT TPEFLPFFEA ATPIHEISRL NIASRPVRRP
     GAPTLQNLRA IPWVMSWTQN RANLPGWYGL REGLREIGVP LARELYAQWP FFRSMLDNAQ
     MSLAKSDLLI FDEYLTLGGP ALGPDLKAAY ADTVALVQDI VGADLLRNEP RLHESIGLRN
     PYIDPIHRLQ VELLRRARRE DGGLDRYERP LLLSVQGIAA GVRNTG
//