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E8TLH3

- E8TLH3_MESCW

UniProt

E8TLH3 - E8TLH3_MESCW

Protein

Elongation factor Tu

Gene

tuf

Organism
Mesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi76 – 805GTPUniRule annotation
    Nucleotide bindingi131 – 1344GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMCIC765698:GHQ5-3651-MONOMER.
    MCIC765698:GHQ5-3672-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:Mesci_3604Imported, Mesci_3624Imported
    OrganismiMesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)Imported
    Taxonomic identifieri765698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
    ProteomesiUP000007471: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiISAPAAC.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E8TLH3-1 [UniParc]FASTAAdd to Basket

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    MAKGKFERNK PHVNIGTIGH VDHGKTSLTA AITKYFGEYK RYDQIDAAPE    50
    EKARGITIST AHVEYETANR HYAHVDCPGH ADYVKNMITG AAQMDGAILV 100
    VSAADGPMPQ TREHILLARQ VGVPSIVVFL NKVDQVDDAE LLELVELEVR 150
    ELLTKNEFPG DDIPIVKGSA LAALEDSDKK IGEDAIRELM AAVDAYIPTP 200
    VRPLDKPFLM PIEDVFSISG RGTVVTGRVE RGVVKVGEEL EIIGIRPTTK 250
    TTCTGVEMFR KLLDQGQAGD NIGALLRGVD REGVERGQVL AKPGTVKPHK 300
    KFVAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGIVS LPEGTEMVMP 350
    GDNITVDVEL IVPIAMEEKL RFAIREGGRT VGAGIVVTIK E 391
    Length:391
    Mass (Da):42,769
    Last modified:April 5, 2011 - v1
    Checksum:i87954F20DF0EB633
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002447 Genomic DNA. Translation: ADV12724.1.
    CP002447 Genomic DNA. Translation: ADV12744.1.
    RefSeqiWP_013531404.1. NC_014923.1.
    YP_004142774.1. NC_014923.1.
    YP_004142794.1. NC_014923.1.

    Genome annotation databases

    EnsemblBacteriaiADV12724; ADV12724; Mesci_3604.
    ADV12744; ADV12744; Mesci_3624.
    GeneIDi10119089.
    10119110.
    KEGGimci:Mesci_3604.
    mci:Mesci_3624.
    PATRICi45257342. VBIMesCic160642_4109.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002447 Genomic DNA. Translation: ADV12724.1 .
    CP002447 Genomic DNA. Translation: ADV12744.1 .
    RefSeqi WP_013531404.1. NC_014923.1.
    YP_004142774.1. NC_014923.1.
    YP_004142794.1. NC_014923.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADV12724 ; ADV12724 ; Mesci_3604 .
    ADV12744 ; ADV12744 ; Mesci_3624 .
    GeneIDi 10119089.
    10119110.
    KEGGi mci:Mesci_3604.
    mci:Mesci_3624.
    PATRICi 45257342. VBIMesCic160642_4109.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi ISAPAAC.

    Enzyme and pathway databases

    BioCyci MCIC765698:GHQ5-3651-MONOMER.
    MCIC765698:GHQ5-3672-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae WSM1271."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G., Tiwari R.P., Woyke T.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: WSM1271Imported.
    2. "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae WSM1271."
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G., Tiwari R.P., Woyke T.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HAMBI 2942 / LMG 23838 / WSM1271Imported.

    Entry informationi

    Entry nameiE8TLH3_MESCW
    AccessioniPrimary (citable) accession number: E8TLH3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3