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E8TGJ4

- E8TGJ4_MESCW

UniProt

E8TGJ4 - E8TGJ4_MESCW

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Protein
Alanine racemase
Gene
Mesci_5615
Organism
Mesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei51 – 511Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei145 – 1451Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciMCIC765698:GHQ5-5677-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mesci_5615Imported
OrganismiMesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)Imported
Taxonomic identifieri765698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
ProteomesiUP000007471: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei51 – 511N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE8TGJ4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000118797.
KOiK01775.
OMAiQTISHEE.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

E8TGJ4-1 [UniParc]FASTAAdd to Basket

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MCALTSIAPV QSKKAASREA WYEIDLGAIR HNYRQLRRHL PRTVKIFACL    50
KRNAYGCGAG PVARTLATEG ADGFAVATLP DAMAIREMGI DLPVLLYPGP 100
LPTSAKTIEA LGLTVTVSSL DELESWRAAM SVTRIFVKAD LGFFRAGATP 150
QEIGRLLAAA HVCSDVEVQG LYAHLSELPT SVTSDASEQF SRLQRILQDA 200
EASGTRPPII MMSSTAGVLR HPAMDLDAVD PGALFIGLPE TDRPMRAVTL 250
RPALKAISTC LVSVKRIDAS LGPIPDIPGF RSGMTIGVLG MGWGDGLPRH 300
VPAQAEALVR GQRARLLPPA HLEHLRIDLT DVPDARFGDQ VLLLGQQAHQ 350
TISHEEVAAQ WGTDLIGLYA QLRDHIPRVY V 381
Length:381
Mass (Da):41,101
Last modified:April 5, 2011 - v1
Checksum:i4D8E7F932A0A0415
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002447 Genomic DNA. Translation: ADV14707.1.
RefSeqiYP_004144757.1. NC_014923.1.

Genome annotation databases

EnsemblBacteriaiADV14707; ADV14707; Mesci_5615.
GeneIDi10121115.
KEGGimci:Mesci_5615.
PATRICi45261463. VBIMesCic160642_6138.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002447 Genomic DNA. Translation: ADV14707.1 .
RefSeqi YP_004144757.1. NC_014923.1.

3D structure databases

ProteinModelPortali E8TGJ4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADV14707 ; ADV14707 ; Mesci_5615 .
GeneIDi 10121115.
KEGGi mci:Mesci_5615.
PATRICi 45261463. VBIMesCic160642_6138.

Phylogenomic databases

HOGENOMi HOG000118797.
KOi K01775.
OMAi QTISHEE.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci MCIC765698:GHQ5-5677-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae WSM1271."
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G., Tiwari R.P., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HAMBI 2942 / LMG 23838 / WSM1271.

Entry informationi

Entry nameiE8TGJ4_MESCW
AccessioniPrimary (citable) accession number: E8TGJ4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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