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E8TGJ4

- E8TGJ4_MESCW

UniProt

E8TGJ4 - E8TGJ4_MESCW

Protein

Alanine racemase

Gene

Mesci_5615

Organism
Mesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei51 – 511Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei145 – 1451SubstrateUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMCIC765698:GHQ5-5677-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Mesci_5615Imported
    OrganismiMesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)Imported
    Taxonomic identifieri765698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
    ProteomesiUP000007471: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei51 – 511N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE8TGJ4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000118797.
    KOiK01775.
    OMAiQTISHEE.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E8TGJ4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MCALTSIAPV QSKKAASREA WYEIDLGAIR HNYRQLRRHL PRTVKIFACL    50
    KRNAYGCGAG PVARTLATEG ADGFAVATLP DAMAIREMGI DLPVLLYPGP 100
    LPTSAKTIEA LGLTVTVSSL DELESWRAAM SVTRIFVKAD LGFFRAGATP 150
    QEIGRLLAAA HVCSDVEVQG LYAHLSELPT SVTSDASEQF SRLQRILQDA 200
    EASGTRPPII MMSSTAGVLR HPAMDLDAVD PGALFIGLPE TDRPMRAVTL 250
    RPALKAISTC LVSVKRIDAS LGPIPDIPGF RSGMTIGVLG MGWGDGLPRH 300
    VPAQAEALVR GQRARLLPPA HLEHLRIDLT DVPDARFGDQ VLLLGQQAHQ 350
    TISHEEVAAQ WGTDLIGLYA QLRDHIPRVY V 381
    Length:381
    Mass (Da):41,101
    Last modified:April 5, 2011 - v1
    Checksum:i4D8E7F932A0A0415
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002447 Genomic DNA. Translation: ADV14707.1.
    RefSeqiYP_004144757.1. NC_014923.1.

    Genome annotation databases

    EnsemblBacteriaiADV14707; ADV14707; Mesci_5615.
    GeneIDi10121115.
    KEGGimci:Mesci_5615.
    PATRICi45261463. VBIMesCic160642_6138.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002447 Genomic DNA. Translation: ADV14707.1 .
    RefSeqi YP_004144757.1. NC_014923.1.

    3D structure databases

    ProteinModelPortali E8TGJ4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADV14707 ; ADV14707 ; Mesci_5615 .
    GeneIDi 10121115.
    KEGGi mci:Mesci_5615.
    PATRICi 45261463. VBIMesCic160642_6138.

    Phylogenomic databases

    HOGENOMi HOG000118797.
    KOi K01775.
    OMAi QTISHEE.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci MCIC765698:GHQ5-5677-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae WSM1271."
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G., Tiwari R.P., Woyke T.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HAMBI 2942 / LMG 23838 / WSM1271Imported.

    Entry informationi

    Entry nameiE8TGJ4_MESCW
    AccessioniPrimary (citable) accession number: E8TGJ4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3