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E8TEA0

- E8TEA0_MESCW

UniProt

E8TEA0 - E8TEA0_MESCW

Protein

Ribulose bisphosphate carboxylase large chain

Gene

cbbL

Organism
Mesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

    Catalytic activityi

    2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
    3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

    Cofactori

    Binds 1 magnesium ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei136 – 1361Substrate; in homodimeric partnerUniRule annotation
    Binding sitei186 – 1861SubstrateUniRule annotation
    Active sitei188 – 1881Proton acceptorUniRule annotation
    Binding sitei190 – 1901SubstrateUniRule annotation
    Metal bindingi214 – 2141Magnesium; via carbamate groupUniRule annotation
    Metal bindingi216 – 2161MagnesiumUniRule annotation
    Metal bindingi217 – 2171MagnesiumUniRule annotation
    Active sitei306 – 3061Proton acceptorUniRule annotation
    Binding sitei307 – 3071SubstrateUniRule annotation
    Binding sitei339 – 3391SubstrateUniRule annotation
    Sitei346 – 3461Transition state stabilizerUniRule annotation
    Binding sitei391 – 3911SubstrateUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. monooxygenase activity Source: UniProtKB-KW
    3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. reductive pentose-phosphate cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

    Keywords - Biological processi

    Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciMCIC765698:GHQ5-4336-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribulose bisphosphate carboxylase large chainUniRule annotation (EC:4.1.1.39UniRule annotation)
    Short name:
    RuBisCO large subunitUniRule annotation
    Gene namesi
    Name:cbbLUniRule annotation
    Ordered Locus Names:Mesci_4283Imported
    OrganismiMesorhizobium ciceri bv. biserrulae (strain HAMBI 2942 / LMG 23838 / WSM1271)Imported
    Taxonomic identifieri765698 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
    ProteomesiUP000007471: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei214 – 2141N6-carboxylysineUniRule annotation

    Interactioni

    Subunit structurei

    Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE8TEA0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000230831.
    KOiK01601.
    OMAiCTPLKQA.

    Family and domain databases

    Gene3Di3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPiMF_01338. RuBisCO_L_type1.
    InterProiIPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view]
    PfamiPF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E8TEA0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKIDILPAG TLKEGKERYK SGVIPYKKMG YWEPDYRPKE TDLIAMFRIT    50
    PQPGVDHEEA AAAIAGESST ATWTVVWTDR LTACELYRAK AFRSEPVPNT 100
    GPGTKTEQQY FAYIAYDLDL FEPGSIANLT ASIIGNVFGF KAVKALRLED 150
    MRIPVAYLKT FQGPATGIVV ERERLDKFGR PLLGATTKPK LGLSGRNYGR 200
    VVYEALKGGL DFVKDDENIN SQPFMHWRDR FLYCMEAVNK ASAATGEVKG 250
    HYLNVTAGTM EEMYERAEFA KQLGSCIVMI DLVIGYTAIQ SMAKWARRND 300
    MILHLHRAGN STYSRQKNHG MNFRVICKWM RMAGVDHIHA GTVVGKLEGD 350
    PLMIKGFYDT LREERTPQNL ETGLFFDQEW ASLNKVMPVA SGGIHAGQMH 400
    QLIHYLGEDV ILQFGGGTIG HPDGIQAGAT ANRVALEAMI LARNEGRDYL 450
    REGTKILEQA ARWCTPLKAA LETWKDVTFN YESTDTADFV PTATPSF 497
    Length:497
    Mass (Da):55,476
    Last modified:April 5, 2011 - v1
    Checksum:i95D543D064004907
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002447 Genomic DNA. Translation: ADV13393.1.
    RefSeqiWP_013532056.1. NC_014923.1.
    YP_004143443.1. NC_014923.1.

    Genome annotation databases

    EnsemblBacteriaiADV13393; ADV13393; Mesci_4283.
    GeneIDi10119774.
    KEGGimci:Mesci_4283.
    PATRICi45258702. VBIMesCic160642_4780.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002447 Genomic DNA. Translation: ADV13393.1 .
    RefSeqi WP_013532056.1. NC_014923.1.
    YP_004143443.1. NC_014923.1.

    3D structure databases

    ProteinModelPortali E8TEA0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADV13393 ; ADV13393 ; Mesci_4283 .
    GeneIDi 10119774.
    KEGGi mci:Mesci_4283.
    PATRICi 45258702. VBIMesCic160642_4780.

    Phylogenomic databases

    HOGENOMi HOG000230831.
    KOi K01601.
    OMAi CTPLKQA.

    Enzyme and pathway databases

    BioCyci MCIC765698:GHQ5-4336-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.110. 1 hit.
    3.30.70.150. 1 hit.
    HAMAPi MF_01338. RuBisCO_L_type1.
    InterProi IPR020878. RuBisCo_large_chain_AS.
    IPR020888. RuBisCO_lsu.
    IPR000685. RuBisCO_lsu_C.
    IPR017443. RuBisCO_lsu_fd_N.
    IPR017444. RuBisCO_lsu_N.
    [Graphical view ]
    Pfami PF00016. RuBisCO_large. 1 hit.
    PF02788. RuBisCO_large_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51649. SSF51649. 1 hit.
    SSF54966. SSF54966. 1 hit.
    PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae WSM1271."
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G., Tiwari R.P., Woyke T.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HAMBI 2942 / LMG 23838 / WSM1271Imported.

    Entry informationi

    Entry nameiE8TEA0_MESCW
    AccessioniPrimary (citable) accession number: E8TEA0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Miscellaneous

    The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3