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E8T632 (E8T632_THEA1) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase A HAMAP-Rule MF_00171

EC=5.4.99.12 HAMAP-Rule MF_00171
Alternative name(s):
tRNA pseudouridine(38-40) synthase HAMAP-Rule MF_00171
tRNA pseudouridylate synthase I HAMAP-Rule MF_00171
tRNA-uridine isomerase I HAMAP-Rule MF_00171
Gene names
Name:truA HAMAP-Rule MF_00171
Ordered Locus Names:Theam_0646 EMBL ADU96616.1
OrganismThermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1) [Complete proteome] [HAMAP] EMBL ADU96616.1
Taxonomic identifier648996 [NCBI]
Taxonomic lineageBacteriaAquificaeAquificalesDesulfurobacteriaceaeThermovibrio

Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs By similarity. HAMAP-Rule MF_00171 SAAS SAAS020097

Catalytic activity

tRNA uridine(38-40) = tRNA pseudouridine(38-40). HAMAP-Rule MF_00171 RuleBase RU003792 SAAS SAAS020097

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00171

Sequence similarities

Belongs to the tRNA pseudouridine synthase TruA family. HAMAP-Rule MF_00171 RuleBase RU003792

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site521Nucleophile By similarity HAMAP-Rule MF_00171 PIRSR PIRSR001430-1
Binding site1101Substrate By similarity HAMAP-Rule MF_00171 PIRSR PIRSR001430-2

Sequences

Sequence LengthMass (Da)Tools
E8T632 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 787DE70850FBB148

FASTA25429,564
        10         20         30         40         50         60 
MRNFKLTVEY LGTNYYGWQF LPDKPTVQGE IIRCLETVLR HPVKLIGASR TDAGVHARGQ 

        70         80         90        100        110        120 
VANFLTAKEV SCEKLLSALN GLLPPDIRVK EVEEVPLEFH ARRSARGKLY RYRLFIRDVP 

       130        140        150        160        170        180 
SPFEFRRSWY LRRTLSVEPM REATQFLVGT HDFTTFSKSE RKREVNPIRT IDKIEITNKE 

       190        200        210        220        230        240 
WEEGVLVELL FTGRSFLRHM VRVIVATLVK VGTGEVKPQE VKEMLQAKDR SRAPFLAPPD 

       250 
GLYLERVFYD DYPY 

« Hide

References

[1]"Complete sequence of chromosome of Thermovibrio ammonificans HB-1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Vetriani C., Woyke T.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 15698 / JCM 12110 / HB-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002444 Genomic DNA. Translation: ADU96616.1.
RefSeqYP_004151257.1. NC_014926.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADU96616; ADU96616; Theam_0646.
GeneID10125683.
KEGGtam:Theam_0646.
PATRIC45383617. VBITheAmm13058_0742.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000248673.
KOK06173.
OMAGKSFLWE.

Enzyme and pathway databases

BioCycTAMM648996:GI3X-665-MONOMER.

Family and domain databases

Gene3D3.30.70.580. 1 hit.
3.30.70.660. 1 hit.
HAMAPMF_00171. TruA.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view]
PANTHERPTHR11142. PTHR11142. 1 hit.
PfamPF01416. PseudoU_synth_1. 2 hits.
[Graphical view]
PIRSFPIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00071. hisT_truA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE8T632_THEA1
AccessionPrimary (citable) accession number: E8T632
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 19, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)