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E8SYK9 (E8SYK9_GEOS2) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Segregation and condensation protein A HAMAP-Rule MF_01805
Gene names
Name:scpA HAMAP-Rule MF_01805
Ordered Locus Names:GYMC52_2271 EMBL ADU94673.1
OrganismGeobacillus sp. (strain Y412MC52) [Complete proteome] [HAMAP] EMBL ADU94673.1
Taxonomic identifier550542 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves By similarity. HAMAP-Rule MF_01805 SAAS SAAS003768

Subunit structure

Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA By similarity. HAMAP-Rule MF_01805 SAAS SAAS003768

Subcellular location

Cytoplasm By similarity SAAS SAAS003768.

Cytoplasm. Note: Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells By similarity. HAMAP-Rule MF_01805

Sequence similarities

Belongs to the ScpA family. HAMAP-Rule MF_01805

Sequences

Sequence LengthMass (Da)Tools
E8SYK9 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 3215B4B478A515DB

FASTA24928,885
        10         20         30         40         50         60 
MQLPYNVKIE AFEGPLDLLL HLINRYEIDI YDIPVAQITE QYMAYIHAMQ ELELDIASEY 

        70         80         90        100        110        120 
LVMAATLLAI KSKMLLPPSN EEAVDGDIEW GDDGDPREEL TQRLLEYKKF KEAARELKRR 

       130        140        150        160        170        180 
EEERALLFTK PPSDLSAYAD EKKAAPLDVN VYDMLGALSK LLRRKKLQKP MRAKISRQDI 

       190        200        210        220        230        240 
SVEQRMAEIL HELKQANGRK NFYELFPSYD RSYIVVTFLA ILELMKQDEI IVEQERNFSD 


LFLAVKPAG 

« Hide

References

« Hide 'large scale' references
[1]"Complete sequence of chromosome of Geobacillus sp. Y412MC52."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Munk C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mead D., Woyke T.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y412MC52 EMBL ADU94673.1.
[2]"Molecular basis of SMC ATPase activation: role of internal structural changes of the regulatory subcomplex ScpAB."
Kamada K., Miyata M., Hirano T.
Structure 21:581-594(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 2-172.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002442 Genomic DNA. Translation: ADU94673.1.
RefSeqYP_004132816.1. NC_014915.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3W6JX-ray2.60A/D2-172[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADU94673; ADU94673; GYMC52_2271.
GeneID10108969.
KEGGgya:GYMC52_2271.
PATRIC45226273. VBIGeoSp94955_2472.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000242824.
KOK05896.

Enzyme and pathway databases

BioCycGSP550542:GH52-2366-MONOMER.

Family and domain databases

HAMAPMF_01805. ScpA.
InterProIPR003768. ScpA.
[Graphical view]
PfamPF02616. ScpA_ScpB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8SYK9_GEOS2
AccessionPrimary (citable) accession number: E8SYK9
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)