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E8SYK8 (E8SYK8_GEOS2) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Segregation and condensation protein B HAMAP-Rule MF_01804
Gene names
Name:scpB HAMAP-Rule MF_01804
Ordered Locus Names:GYMC52_2270 EMBL ADU94672.1
OrganismGeobacillus sp. (strain Y412MC52) [Complete proteome] [HAMAP] EMBL ADU94672.1
Taxonomic identifier550542 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves By similarity. HAMAP-Rule MF_01804 SAAS SAAS005234

Subunit structure

Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA By similarity. HAMAP-Rule MF_01804 SAAS SAAS005234

Subcellular location

Cytoplasm By similarity SAAS SAAS005234.

Cytoplasm. Note: Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells By similarity. HAMAP-Rule MF_01804

Sequence similarities

Belongs to the ScpB family. HAMAP-Rule MF_01804

Sequences

Sequence LengthMass (Da)Tools
E8SYK8 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: DA927D893B632927

FASTA27330,247
        10         20         30         40         50         60 
MAAAVRCGGP LFFCCLFAHA MIRRRVDSHW GEKTWETTKT GGKEEGRQRV WRGRRAMEQN 

        70         80         90        100        110        120 
EREKKGAGAL KPAKAIVEAL LFAAGDEGLS LSQIAAVLEV SELEAKAVIE ELQQDCRREE 

       130        140        150        160        170        180 
RGIQLVELGG VFLLATKKEH APYLKKLVEA PGASPLSQAA LETLAIIAYR QPITRAEIEE 

       190        200        210        220        230        240 
IRGVKSDKPL QTLMARALIK EVGRAEGTGR PILYGTTPEF LDYFGLKTLE ELPPLPEWAD 

       250        260        270 
DGESEREADL FFEKLAENLS DGQPEYGKLK KNG 

« Hide

References

« Hide 'large scale' references
[1]"Complete sequence of chromosome of Geobacillus sp. Y412MC52."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Munk C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mead D., Woyke T.
Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Y412MC52 EMBL ADU94672.1.
[2]"Molecular basis of SMC ATPase activation: role of internal structural changes of the regulatory subcomplex ScpAB."
Kamada K., Miyata M., Hirano T.
Structure 21:581-594(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.37 ANGSTROMS) OF 68-155.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002442 Genomic DNA. Translation: ADU94672.1.
RefSeqYP_004132815.1. NC_014915.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3W6JX-ray2.60B/C/E/F68-247[»]
3W6KX-ray2.37B/C/E/F68-155[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADU94672; ADU94672; GYMC52_2270.
GeneID10108968.
KEGGgya:GYMC52_2270.
PATRIC45226271. VBIGeoSp94955_2471.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000242838.
KOK06024.

Enzyme and pathway databases

BioCycGSP550542:GH52-2365-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 2 hits.
HAMAPMF_01804. ScpB.
InterProIPR005234. ScpB_csome_segregation.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF04079. DUF387. 1 hit.
[Graphical view]
PIRSFPIRSF019345. ScpB. 1 hit.
TIGRFAMsTIGR00281. TIGR00281. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE8SYK8_GEOS2
AccessionPrimary (citable) accession number: E8SYK8
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 19, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)