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Protein
Submitted name:

Alpha amylase catalytic region protein

Gene

GYMC52_3303

Organism
Geobacillus sp. (strain Y412MC52)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei268 – 2681NucleophileUniRule annotation
Active sitei298 – 2981Proton donorUniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciGSP550542:GH52-3418-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha amylase catalytic region proteinImported
Gene namesi
Ordered Locus Names:GYMC52_3303Imported
OrganismiGeobacillus sp. (strain Y412MC52)Imported
Taxonomic identifieri550542 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
ProteomesiUP000002223: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3535 PotentialImportedAdd
BLAST

Structurei

3D structure databases

ProteinModelPortaliE8SWW3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

HOGENOMiHOG000094847.
KOiK01176.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015237. Alpha-amylase_C_pro.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF09154. DUF1939. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E8SWW3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLTFHRIIRK GWMFLLAFLL TASLFCPTGQ PAKAAAPFNG TMMQYFEWYL
60 70 80 90 100
PDDGALWTKV ANEANNLSSL GITALWLPPA YKGTSRSDVG YGVYDLYDLG
110 120 130 140 150
EFNQKGTVRT KYGTKAQYLQ AIQAAHAAGM QVYADVVFDH KGGADGTEWV
160 170 180 190 200
DAVEVNPSDR NQEISGTYQI QAWTKFDFPG RGNTYSSFKW RWYHFDGVDW
210 220 230 240 250
DESRKLSRIY KFRGIGKAWD WEVDTENGNY DYLMYADLDM DHPEVVTELK
260 270 280 290 300
NWGKWYVNTT NIDGFRLDAV KHIKFSFFPD WLSYVRSQTG KPLFTVGEYW
310 320 330 340 350
SYDINKLHNY ITKTNGTMSL FDAPLHNKFY TASKSGGAFD MRTLMTNTLM
360 370 380 390 400
KDQPTLAVTF VDNHDTEPGQ ALQSWVDPWF KPLAYAFILT RQEGYPCVFY
410 420 430 440 450
GDYYGIPQYN IPSLKSKIDP LLIARRDYAY GTQHDYLDHS DIIGWTREGV
460 470 480 490 500
TEKPGSGLAA LITDGPGGSK WMYVGKQHAG KVFYDLTGNR SDTVTINSDG
510 520 530 540
WGEFKVNGGS VSVWVPRKTT VSTIAWPITT RPWTGEFVRW TEPRLVAWP
Length:549
Mass (Da):62,611
Last modified:April 5, 2011 - v1
Checksum:i41212347066E7994
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002442 Genomic DNA. Translation: ADU95655.1.
RefSeqiYP_004133798.1. NC_014915.1.

Genome annotation databases

EnsemblBacteriaiADU95655; ADU95655; GYMC52_3303.
GeneIDi10110021.
KEGGigya:GYMC52_3303.
PATRICi45228542. VBIGeoSp94955_3579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002442 Genomic DNA. Translation: ADU95655.1.
RefSeqiYP_004133798.1. NC_014915.1.

3D structure databases

ProteinModelPortaliE8SWW3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADU95655; ADU95655; GYMC52_3303.
GeneIDi10110021.
KEGGigya:GYMC52_3303.
PATRICi45228542. VBIGeoSp94955_3579.

Phylogenomic databases

HOGENOMiHOG000094847.
KOiK01176.

Enzyme and pathway databases

BioCyciGSP550542:GH52-3418-MONOMER.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015237. Alpha-amylase_C_pro.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF09154. DUF1939. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Geobacillus sp. Y412MC52."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Munk C., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mead D., Woyke T.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Y412MC52Imported.

Entry informationi

Entry nameiE8SWW3_GEOS2
AccessioniPrimary (citable) accession number: E8SWW3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.