E8SQM3 (E8SQM3_NEIGO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

ORF Names:

NGTW08_1189 EMBL ADV08157.1

Organism

Neisseria gonorrhoeae TCDC-NG08107 EMBL ADV08157.1

Taxonomic identifier

940296 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › Neisseria gonorrhoeae

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 RuleBase RU000608
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E8SQM3 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 434CED1AF8C1359D	FASTA	352	38,874
	10 20 30 40 50 60 MRPLNVQIRL GNLRHNYRIL KEMHGGKLLA VVKADAYGHG AVRCAFALAD LADGFAVATI 70 80 90 100 110 120 DEGIRLRESG ITHPIVLLEG VFEASEYEAV EQYSLWPAVG NQWQLEALLS RHWKKPVKVW 130 140 150 160 170 180 LKMDSGMHRT GFFPHDYASA YAALKQSEYV DSIVKFSHFS CADEPESGMT EIQMEAFDLG 190 200 210 220 230 240 TKGLEGEESL ANSAAILNIP EARRDWGRAG LALYGISPFG GNDDRLKPVM RLSTRIFGER 250 260 270 280 290 300 VLQPHSPIGY GATFYTSKST RVGLIACGYA DGYPRRAPSN SPVAVDGKLT RVIGRISMDM 310 320 330 340 350 MTIELDASQE GLGHEVELWG DTVNINTVAE AAGTIPYELM CNIKRAKFTY IE

References

[1]

Chen C.-C., Hsia K.-C., Huang C.-T., Wong W.-W., Yen M.-Y., Li L.-H., Lin K.-Y., Chen K.-W., Li S.-Y. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: TCDC-NG08107 EMBL ADV08157.1.

[2]

"Draft Genome Sequence of a Dominant, Multidrug-Resistant Neisseria gonorrhoeae Strain, TCDC-NG08107, from a Sexual Group at High Risk of Acquiring Human Immunodeficiency Virus Infection and Syphilis." Chen C.C., Hsia K.C., Huang C.T., Wong W.W., Yen M.Y., Li L.H., Lin K.Y., Chen K.W., Li S.Y. J. Bacteriol. 193:1788-1789(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: TCDC-NG08107 EMBL ADV08157.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002440 Genomic DNA. Translation: ADV08157.1.
RefSeq	YP_005890020.1. NC_017511.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADV08157; ADV08157; NGTW08_1189.
GeneID	12406483.
KEGG	ngt:NGTW08_1189.
PATRIC	45471860. VBINeiGon174987_1474.
Phylogenomic databases
KO	K01775.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E8SQM3_NEIGO

Accession

Primary (citable) accession number: E8SQM3

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	April 3, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)