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E8SMH4 (E8SMH4_NEIGO) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
ORF Names:NGTW08_1778 EMBL ADV08733.1
OrganismNeisseria gonorrhoeae TCDC-NG08107 [Complete proteome] EMBL ADV08733.1
Taxonomic identifier940296 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length923 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1631 By similarity HAMAP-Rule MF_00595
Active site5911 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
E8SMH4 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: E49B24545074350A

FASTA923103,906
        10         20         30         40         50         60 
MNGLARMRHL RYIYSIYGNE RKIMQLHILN NPKDAALAAD AEFLKQSLFN LLHEEASPLV 

        70         80         90        100        110        120 
VETVKLLSTS DDSAALIEKV LPQLDERQTY DLTLACGLFA QILNIAEDVH HERRRQIHED 

       130        140        150        160        170        180 
AGHNAAEGSL TETVRRLKAG KADGKSVQRQ LDNTSVTAVL TAHPTEVQRQ TVLNFNRRIR 

       190        200        210        220        230        240 
ALLPQRERCT NADALARLRR EIDTVLLGLW QTSETRRHKL SVNDEINNGV SIFPMSFFEA 

       250        260        270        280        290        300 
LPKLYRKMEH DFQTAYPDVR VPNILKIGGW IGGDRDGNPF VSGETLRFAF RRHADAVFRF 

       310        320        330        340        350        360 
YRSELDKLYR ELPLSIRRVK VNDDVMALAA LSPDEEIART EEPYRRAIAY IMARAMGKAR 

       370        380        390        400        410        420 
SLGLGMGCKF GFLEPYASAQ KFLDDLKKLQ RSLIDNGSRL LAEGRLADLI RSVSVFGFHM 

       430        440        450        460        470        480 
MPLDLRQHAG KHADVVAELF QHAGLEDYNS LNEEQKQAAL LRELGHQRPL YSPFITYSDH 

       490        500        510        520        530        540 
TCRELAIFNE ARKIKDEFGE DAVTQSIISN CEQPGDLLAL ALLLKESGLL AVENGKPHSR 

       550        560        570        580        590        600 
INIVPLFETI EALENACPVM ETMFRLDWYD ALLESRGNIQ EIMLGYSDSN KDGGYVTSSW 

       610        620        630        640        650        660 
CLHQAELGLV ELFKKYDVRM RLFHGRGGSV GRGGGPSYQA ILAQPAGSVA GQIRITEQGE 

       670        680        690        700        710        720 
VITAKYADPG NAQRNLETLV AATLEASILP DKKDPDAKLM QALSDVSFKY YRELITHPDF 

       730        740        750        760        770        780 
IDYFLQTSPI QEIATLNLGS RPASRKTLAR IQDLRAIPWV FSWMQNRLML PAWYGFGSAV 

       790        800        810        820        830        840 
ETLCEGSPET LAALRGHAQN NPFFQAMLSN MEQVMAKTDI TLAENYAGLS ESPEKAKVIF 

       850        860        870        880        890        900 
GMIKEEYRRS RKALLDLLQT EELLRDNRSL ARSLALRIPY LNALNGLQVA MLKRLRKEPD 

       910        920 
NPHALLMVHL TINGVAQGLR NTG 

« Hide

References

[1]Chen C.-C., Hsia K.-C., Huang C.-T., Wong W.-W., Yen M.-Y., Li L.-H., Lin K.-Y., Chen K.-W., Li S.-Y.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: TCDC-NG08107 EMBL ADV08733.1.
[2]"Draft genome sequence of a dominant, multidrug-resistant Neisseria gonorrhoeae strain, TCDC-NG08107, from a sexual group at high risk of acquiring human immunodeficiency virus infection and syphilis."
Chen C.C., Hsia K.C., Huang C.T., Wong W.W., Yen M.Y., Li L.H., Lin K.Y., Chen K.W., Li S.Y.
J. Bacteriol. 193:1788-1789(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: TCDC-NG08107 EMBL ADV08733.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002440 Genomic DNA. Translation: ADV08733.1.
RefSeqYP_005890596.1. NC_017511.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADV08733; ADV08733; NGTW08_1778.
GeneID12407083.
KEGGngt:NGTW08_1778.
PATRIC45473418. VBINeiGon174987_2204.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01595.

Enzyme and pathway databases

BioCycNGON940296:GLHN-1796-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8SMH4_NEIGO
AccessionPrimary (citable) accession number: E8SMH4
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)