E8SM44 (E8SM44_NEIGO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Multidrug efflux protein EMBL ADV07402.1

Gene names

ORF Names:

NGTW08_0430 EMBL ADV07402.1

Organism

Neisseria gonorrhoeae TCDC-NG08107 EMBL ADV07402.1

Taxonomic identifier

940296 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › Neisseria gonorrhoeae

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4HUK PDB 4HUL PDB 4HUM PDB 4HUN
Gene Ontology (GO)
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	antiporter activity Inferred from electronic annotation. Source: InterPro drug transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E8SM44 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 0B0AC1EDC75DA7FB	FASTA	459	49,811
	10 20 30 40 50 60 MLLDLDRFSF SVFLKEIRLL TALALPMLLA QVAQVGIGFV DTVMAGGAGK EDLAAVALGS 70 80 90 100 110 120 SAFATVYITF MGIMAALNPM IAQLYGAGKT GEAGETGRQG IWFGLILGIF GMILMWAAIT 130 140 150 160 170 180 PFRNWLTLSD YVEGTMAQYM LFTSLAMPAA MVHRALHAYA SSLNRPRLIM LVSFAAFVLN 190 200 210 220 230 240 VPLNYIFVYG KFGMPALGGA GCGVATMAVF WFSALALWIY IAKEKFFRPF GLTAKFGKPD 250 260 270 280 290 300 WAVFKQIWKI GAPIGLSYFL EASAFSFIVF LIAPFGEDYV AAQQVGISLS GILYMIPQSV 310 320 330 340 350 360 GSAGTVRIGF SLGRREFSRA RYISGVSLVS GWVLAVITVL SLVLFRSPLA SMYNDDPAVL 370 380 390 400 410 420 SIASTVLLFA GLFQPADFTQ CIASYALRGY KVTKVPMFIH AAAFWGCGLL PGYLLAYRFD 430 440 450 MGIYGFWTAL IASLTIAAVA LVWCLEKYSM ELVKSHKAV

References

[1]	Chen C.-C., Hsia K.-C., Huang C.-T., Wong W.-W., Yen M.-Y., Li L.-H., Lin K.-Y., Chen K.-W., Li S.-Y. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: TCDC-NG08107 EMBL ADV07402.1.
[2]	"Draft Genome Sequence of a Dominant, Multidrug-Resistant Neisseria gonorrhoeae Strain, TCDC-NG08107, from a Sexual Group at High Risk of Acquiring Human Immunodeficiency Virus Infection and Syphilis." Chen C.C., Hsia K.C., Huang C.T., Wong W.W., Yen M.Y., Li L.H., Lin K.Y., Chen K.W., Li S.Y. J. Bacteriol. 193:1788-1789(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: TCDC-NG08107 EMBL ADV07402.1.
[3]	"Structures of a Na+-coupled, substrate-bound MATE multidrug transporter." Lu M., Symersky J., Radchenko M., Koide A., Guo Y., Nie R., Koide S. Proc. Natl. Acad. Sci. U.S.A. 110:2099-2104(2013) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.49 ANGSTROMS) OF 5-459.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP002440 Genomic DNA. Translation: ADV07402.1.

RefSeq

YP_005889265.1. NC_017511.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4HUK	X-ray	3.59	A	5-459	[»]
4HUL	X-ray	3.81	A	5-459	[»]
4HUM	X-ray	3.49	A	5-459	[»]
4HUN	X-ray	3.59	A	5-459	[»]

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ADV07402; ADV07402; NGTW08_0430.

GeneID

12405721.

KEGG

ngt:NGTW08_0430.

PATRIC

45469942. VBINeiGon174987_0550.

Phylogenomic databases

KO

K03327.

Family and domain databases

InterPro

IPR002528. MATE.
[Graphical view]

Pfam

PF01554. MatE. 2 hits.
[Graphical view]

TIGRFAMs

TIGR00797. matE. 1 hit.

ProtoNet

Search...

Entry information

Entry name

E8SM44_NEIGO

Accession

Primary (citable) accession number: E8SM44

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)