Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E8SM44

- E8SM44_NEIGO

UniProt

E8SM44 - E8SM44_NEIGO

Protein
Submitted name:

Multidrug efflux protein

Gene

NGTW08_0430

Organism
Neisseria gonorrhoeae TCDC-NG08107
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 13 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. antiporter activity Source: InterPro
    2. drug transmembrane transporter activity Source: InterPro

    Enzyme and pathway databases

    BioCyciNGON940296:GLHN-434-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Multidrug efflux proteinImported
    Gene namesi
    ORF Names:NGTW08_0430Imported
    OrganismiNeisseria gonorrhoeae TCDC-NG08107
    Taxonomic identifieri940296 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4HUKX-ray3.59A5-459[»]
    4HULX-ray3.81A5-459[»]
    4HUMX-ray3.49A5-459[»]
    4HUNX-ray3.59A5-459[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK03327.

    Family and domain databases

    InterProiIPR002528. MATE.
    [Graphical view]
    PfamiPF01554. MatE. 2 hits.
    [Graphical view]
    TIGRFAMsiTIGR00797. matE. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E8SM44-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLDLDRFSF SVFLKEIRLL TALALPMLLA QVAQVGIGFV DTVMAGGAGK    50
    EDLAAVALGS SAFATVYITF MGIMAALNPM IAQLYGAGKT GEAGETGRQG 100
    IWFGLILGIF GMILMWAAIT PFRNWLTLSD YVEGTMAQYM LFTSLAMPAA 150
    MVHRALHAYA SSLNRPRLIM LVSFAAFVLN VPLNYIFVYG KFGMPALGGA 200
    GCGVATMAVF WFSALALWIY IAKEKFFRPF GLTAKFGKPD WAVFKQIWKI 250
    GAPIGLSYFL EASAFSFIVF LIAPFGEDYV AAQQVGISLS GILYMIPQSV 300
    GSAGTVRIGF SLGRREFSRA RYISGVSLVS GWVLAVITVL SLVLFRSPLA 350
    SMYNDDPAVL SIASTVLLFA GLFQPADFTQ CIASYALRGY KVTKVPMFIH 400
    AAAFWGCGLL PGYLLAYRFD MGIYGFWTAL IASLTIAAVA LVWCLEKYSM 450
    ELVKSHKAV 459
    Length:459
    Mass (Da):49,811
    Last modified:April 5, 2011 - v1
    Checksum:i0B0AC1EDC75DA7FB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002440 Genomic DNA. Translation: ADV07402.1.
    RefSeqiWP_003687823.1. NC_017511.1.
    YP_005889265.1. NC_017511.1.

    Genome annotation databases

    EnsemblBacteriaiADV07402; ADV07402; NGTW08_0430.
    GeneIDi12405721.
    KEGGingt:NGTW08_0430.
    PATRICi45469942. VBINeiGon174987_0550.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002440 Genomic DNA. Translation: ADV07402.1 .
    RefSeqi WP_003687823.1. NC_017511.1.
    YP_005889265.1. NC_017511.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4HUK X-ray 3.59 A 5-459 [» ]
    4HUL X-ray 3.81 A 5-459 [» ]
    4HUM X-ray 3.49 A 5-459 [» ]
    4HUN X-ray 3.59 A 5-459 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADV07402 ; ADV07402 ; NGTW08_0430 .
    GeneIDi 12405721.
    KEGGi ngt:NGTW08_0430.
    PATRICi 45469942. VBINeiGon174987_0550.

    Phylogenomic databases

    KOi K03327.

    Enzyme and pathway databases

    BioCyci NGON940296:GLHN-434-MONOMER.

    Family and domain databases

    InterProi IPR002528. MATE.
    [Graphical view ]
    Pfami PF01554. MatE. 2 hits.
    [Graphical view ]
    TIGRFAMsi TIGR00797. matE. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Chen C.-C., Hsia K.-C., Huang C.-T., Wong W.-W., Yen M.-Y., Li L.-H., Lin K.-Y., Chen K.-W., Li S.-Y.
      Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: TCDC-NG08107Imported.
    2. "Draft genome sequence of a dominant, multidrug-resistant Neisseria gonorrhoeae strain, TCDC-NG08107, from a sexual group at high risk of acquiring human immunodeficiency virus infection and syphilis."
      Chen C.C., Hsia K.C., Huang C.T., Wong W.W., Yen M.Y., Li L.H., Lin K.Y., Chen K.W., Li S.Y.
      J. Bacteriol. 193:1788-1789(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TCDC-NG08107Imported.
    3. "Structures of a Na+-coupled, substrate-bound MATE multidrug transporter."
      Lu M., Symersky J., Radchenko M., Koide A., Guo Y., Nie R., Koide S.
      Proc. Natl. Acad. Sci. U.S.A. 110:2099-2104(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.49 ANGSTROMS) OF 5-459.

    Entry informationi

    Entry nameiE8SM44_NEIGO
    AccessioniPrimary (citable) accession number: E8SM44
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 13 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3