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E8SM44

- E8SM44_NEIGO

UniProt

E8SM44 - E8SM44_NEIGO

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Protein
Submitted name: Multidrug efflux protein
Gene
NGTW08_0430
Organism
Neisseria gonorrhoeae TCDC-NG08107
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. antiporter activity Source: InterPro
  2. drug transmembrane transporter activity Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciNGON940296:GLHN-434-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Multidrug efflux proteinImported
Gene namesi
ORF Names:NGTW08_0430Imported
OrganismiNeisseria gonorrhoeae TCDC-NG08107Imported
Taxonomic identifieri940296 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000007470: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HUKX-ray3.59A5-459[»]
4HULX-ray3.81A5-459[»]
4HUMX-ray3.49A5-459[»]
4HUNX-ray3.59A5-459[»]

Family & Domainsi

Phylogenomic databases

KOiK03327.

Family and domain databases

InterProiIPR002528. MATE.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00797. matE. 1 hit.

Sequencei

Sequence statusi: Complete.

E8SM44-1 [UniParc]FASTAAdd to Basket

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MLLDLDRFSF SVFLKEIRLL TALALPMLLA QVAQVGIGFV DTVMAGGAGK    50
EDLAAVALGS SAFATVYITF MGIMAALNPM IAQLYGAGKT GEAGETGRQG 100
IWFGLILGIF GMILMWAAIT PFRNWLTLSD YVEGTMAQYM LFTSLAMPAA 150
MVHRALHAYA SSLNRPRLIM LVSFAAFVLN VPLNYIFVYG KFGMPALGGA 200
GCGVATMAVF WFSALALWIY IAKEKFFRPF GLTAKFGKPD WAVFKQIWKI 250
GAPIGLSYFL EASAFSFIVF LIAPFGEDYV AAQQVGISLS GILYMIPQSV 300
GSAGTVRIGF SLGRREFSRA RYISGVSLVS GWVLAVITVL SLVLFRSPLA 350
SMYNDDPAVL SIASTVLLFA GLFQPADFTQ CIASYALRGY KVTKVPMFIH 400
AAAFWGCGLL PGYLLAYRFD MGIYGFWTAL IASLTIAAVA LVWCLEKYSM 450
ELVKSHKAV 459
Length:459
Mass (Da):49,811
Last modified:April 5, 2011 - v1
Checksum:i0B0AC1EDC75DA7FB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002440 Genomic DNA. Translation: ADV07402.1.
RefSeqiWP_003687823.1. NC_017511.1.
YP_005889265.1. NC_017511.1.

Genome annotation databases

EnsemblBacteriaiADV07402; ADV07402; NGTW08_0430.
GeneIDi12405721.
KEGGingt:NGTW08_0430.
PATRICi45469942. VBINeiGon174987_0550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002440 Genomic DNA. Translation: ADV07402.1 .
RefSeqi WP_003687823.1. NC_017511.1.
YP_005889265.1. NC_017511.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4HUK X-ray 3.59 A 5-459 [» ]
4HUL X-ray 3.81 A 5-459 [» ]
4HUM X-ray 3.49 A 5-459 [» ]
4HUN X-ray 3.59 A 5-459 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADV07402 ; ADV07402 ; NGTW08_0430 .
GeneIDi 12405721.
KEGGi ngt:NGTW08_0430.
PATRICi 45469942. VBINeiGon174987_0550.

Phylogenomic databases

KOi K03327.

Enzyme and pathway databases

BioCyci NGON940296:GLHN-434-MONOMER.

Family and domain databases

InterProi IPR002528. MATE.
[Graphical view ]
Pfami PF01554. MatE. 2 hits.
[Graphical view ]
TIGRFAMsi TIGR00797. matE. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Draft genome sequence of a dominant, multidrug-resistant Neisseria gonorrhoeae strain, TCDC-NG08107, from a sexual group at high risk of acquiring human immunodeficiency virus infection and syphilis."
    Chen C.C., Hsia K.C., Huang C.T., Wong W.W., Yen M.Y., Li L.H., Lin K.Y., Chen K.W., Li S.Y.
    J. Bacteriol. 193:1788-1789(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TCDC-NG08107Imported.
  2. "Structures of a Na+-coupled, substrate-bound MATE multidrug transporter."
    Lu M., Symersky J., Radchenko M., Koide A., Guo Y., Nie R., Koide S.
    Proc. Natl. Acad. Sci. U.S.A. 110:2099-2104(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.49 ANGSTROMS) OF 5-459.

Entry informationi

Entry nameiE8SM44_NEIGO
AccessioniPrimary (citable) accession number: E8SM44
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 3, 2014
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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