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Protein

50S ribosomal protein L1

Gene

rplA

Organism
Staphylococcus pseudintermedius (strain HKU10-03)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.UniRule annotation
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

RepressorUniRule annotation, Ribonucleoprotein, Ribosomal proteinUniRule annotation

Keywords - Biological processi

Translation regulationUniRule annotation

Keywords - Ligandi

RNA-binding, rRNA-bindingUniRule annotation, tRNA-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSPSE937773:GH0P-232-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L1UniRule annotation
Gene namesi
Name:rplAUniRule annotation
Ordered Locus Names:SPSINT_0212Imported
OrganismiStaphylococcus pseudintermedius (strain HKU10-03)Imported
Taxonomic identifieri937773 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000007469 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L1P family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000207015.
KOiK02863.
OMAiINAVQDY.

Family and domain databases

Gene3Di3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
HAMAPiMF_01318_B. Ribosomal_L1_B.
InterProiIPR005878. Ribosom_L1_bac-type.
IPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
IPR023673. Ribosomal_L1_CS.
[Graphical view]
PfamiPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMiSSF56808. SSF56808. 1 hit.
TIGRFAMsiTIGR01169. rplA_bact. 1 hit.
PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8SJ17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKGKKYQE ALNKVDRQAL YTVEEAIRLA QETSIANFDA SVEVAFRLGI
60 70 80 90 100
DTRKNDQQIR GAVVLPHGTG KSQRVLVFAK GDKIAEAEAA GADYVGDAEY
110 120 130 140 150
VNKIQQGWFD FDVVVATPDM MGEVGKLGRV LGPKGLMPNP KTGTVTMDVK
160 170 180 190 200
KAVEEIKAGK VEYRAEKAGI VHASIGKVSF ETEKLVENFK TLQDVLTKAK
210 220 230
PSSAKGTYFK SVAVTTTMGP GIKVDTATFK L
Length:231
Mass (Da):25,001
Last modified:April 5, 2011 - v1
Checksum:i5D9B8DDFAF984946
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002439 Genomic DNA. Translation: ADV04741.1.
RefSeqiWP_014614754.1. NC_014925.1.
YP_004148377.1. NC_014925.1.

Genome annotation databases

EnsemblBacteriaiADV04741; ADV04741; SPSINT_0212.
KEGGissd:SPSINT_0212.
PATRICi45363607. VBIStaPse177932_0211.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002439 Genomic DNA. Translation: ADV04741.1.
RefSeqiWP_014614754.1. NC_014925.1.
YP_004148377.1. NC_014925.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADV04741; ADV04741; SPSINT_0212.
KEGGissd:SPSINT_0212.
PATRICi45363607. VBIStaPse177932_0211.

Phylogenomic databases

HOGENOMiHOG000207015.
KOiK02863.
OMAiINAVQDY.

Enzyme and pathway databases

BioCyciSPSE937773:GH0P-232-MONOMER.

Family and domain databases

Gene3Di3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
HAMAPiMF_01318_B. Ribosomal_L1_B.
InterProiIPR005878. Ribosom_L1_bac-type.
IPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
IPR023673. Ribosomal_L1_CS.
[Graphical view]
PfamiPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMiSSF56808. SSF56808. 1 hit.
TIGRFAMsiTIGR01169. rplA_bact. 1 hit.
PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Staphylococcus pseudintermedius."
    Tse H., Tsoi H.W., Leung S.P., Urquhart I.J., Lau S.K.P., Woo P.C.Y., Yuen K.Y.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HKU10-03.
  2. "Complete genome sequence of the veterinary pathogen Staphylococcus pseudintermedius strain HKU10-03, isolated in a case of canine pyoderma."
    Tse H., Tsoi H.W., Leung S.P., Urquhart I.J., Lau S.K., Woo P.C., Yuen K.Y.
    J. Bacteriol. 193:1783-1784(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HKU10-03Imported.

Entry informationi

Entry nameiE8SJ17_STAPH
AccessioniPrimary (citable) accession number: E8SJ17
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 27, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.