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E8SHF5 (E8SHF5_STAPH) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nucleoside diphosphate kinase HAMAP-Rule MF_00451
Short name=NDK HAMAP-Rule MF_00451
Short name=NDP kinase HAMAP-Rule MF_00451
EC=2.7.4.6 HAMAP-Rule MF_00451
Alternative name(s):
Nucleoside-2-P kinase HAMAP-Rule MF_00451
Gene names
Name:ndk HAMAP-Rule MF_00451
Ordered Locus Names:SPSINT_1170
OrganismStaphylococcus pseudintermedius (strain HKU10-03) [Complete proteome] [HAMAP] EMBL ADV05698.1
Taxonomic identifier937773 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length150 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate By similarity. HAMAP-Rule MF_00451

Catalytic activity

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. HAMAP-Rule MF_00451 RuleBase RU004013

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00451

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00451

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00451.

Sequence similarities

Belongs to the NDK family. HAMAP-Rule MF_00451 RuleBase RU004011

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1151Pros-phosphohistidine intermediate By similarity HAMAP-Rule MF_00451
Binding site91ATP By similarity HAMAP-Rule MF_00451
Binding site571ATP By similarity HAMAP-Rule MF_00451
Binding site851ATP By similarity HAMAP-Rule MF_00451
Binding site911ATP By similarity HAMAP-Rule MF_00451
Binding site1021ATP By similarity HAMAP-Rule MF_00451
Binding site1121ATP By similarity HAMAP-Rule MF_00451

Sequences

Sequence LengthMass (Da)Tools
E8SHF5 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 1090FA79EE18D695

FASTA15016,485
        10         20         30         40         50         60 
MEKSFVMIKP DAVQRKLIGE IVQRIEQKGL KLVGAKLMTV PQSLAETHYG EHKGKPFYDS 

        70         80         90        100        110        120 
LISFITSAPV FAMVVEGENA VAVARHIIGS TNPSEATPGS IRGDLGLTVG RNVIHGSDSV 

       130        140        150 
ESAEREIGLW FKDEEISSYH TPDETWLYEA

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Staphylococcus pseudintermedius."
Tse H., Tsoi H.W., Leung S.P., Urquhart I.J., Lau S.K.P., Woo P.C.Y., Yuen K.Y.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: HKU10-03.
[2]"Complete genome sequence of the veterinary pathogen Staphylococcus pseudintermedius strain HKU10-03, isolated in a case of canine pyoderma."
Tse H., Tsoi H.W., Leung S.P., Urquhart I.J., Lau S.K., Woo P.C., Yuen K.Y.
J. Bacteriol. 193:1783-1784(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HKU10-03.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002439 Genomic DNA. Translation: ADV05698.1.
RefSeqYP_004149334.1. NC_014925.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADV05698; ADV05698; SPSINT_1170.
GeneID10135934.
KEGGssd:SPSINT_1170.
PATRIC45365538. VBIStaPse177932_1169.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000224564.
KOK00940.

Family and domain databases

Gene3D3.30.70.141. 1 hit.
HAMAPMF_00451. NDP_kinase.
InterProIPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
[Graphical view]
PANTHERPTHR11349. PTHR11349. 1 hit.
PfamPF00334. NDK. 1 hit.
[Graphical view]
PRINTSPR01243. NUCDPKINASE.
SMARTSM00562. NDK. 1 hit.
[Graphical view]
SUPFAMSSF54919. NDK. 1 hit.
PROSITEPS00469. NDP_KINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8SHF5_STAPH
AccessionPrimary (citable) accession number: E8SHF5
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 1, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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