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E8S0H6 (E8S0H6_MICSL) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595

Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595
Gene names
Name:ppc HAMAP-Rule MF_00595
Ordered Locus Names:ML5_1124 EMBL ADU06664.1
OrganismMicromonospora sp. (strain L5) [Complete proteome] [HAMAP] EMBL ADU06664.1
Taxonomic identifier648999 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeMicromonospora

Protein attributes

Sequence length928 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS021135

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS021135

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1371 By similarity HAMAP-Rule MF_00595
Active site5741 By similarity HAMAP-Rule MF_00595

Sequences

Sequence LengthMass (Da)Tools
E8S0H6 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: D1E43C40E16B1C51

FASTA928101,580
        10         20         30         40         50         60 
MTDQHDHDGP DAALRADIRR LGTLLGQTLA RQEGRPLLDL VEEIRAQVRS DVPAAAQRLA 

        70         80         90        100        110        120 
GLDVTTGTKL ARAFSTYFHL ANITEQVHRA RDLRRRRATH GGWLDQAAKM IAERGVPAEE 

       130        140        150        160        170        180 
IAAAARRLAV RPVFTAHPTE AARRSILSKL RAVADELDTE TANAILYGAS DEGPANRRLA 

       190        200        210        220        230        240 
ELLDLMWQTD ELRLDRPDPT DEARNAIYYL RDLYAEAAPQ VLDDLADTLR TLGVETSPTS 

       250        260        270        280        290        300 
RPLSFGTWIG GDRDGNPFVT PVVTREVLRI QHEHGIAATE KAMDELITEV SVSRRLRAVS 

       310        320        330        340        350        360 
LDLSASLAKD LDALPEVAPR FRRVNAEEPY RLKARCVKAK LANTRERLRA DTPHVPGRDY 

       370        380        390        400        410        420 
RGSSELIADL ELLRASLARN SGQLTAVGRL ASAIRTVSAF GLHLATMDIR EHAEKHHEVL 

       430        440        450        460        470        480 
AQLYEAVGEV SDYPALSRLE RTKLLADELT GRRPLSTQDS PLTESARKTF DVFAAIREAQ 

       490        500        510        520        530        540 
DRFGPEVIES YIISMTLGVD DVLAAVVLAR EAGLVDVHSG RARIGIVPLL ETPAELNAGG 

       550        560        570        580        590        600 
ELLDELLSLP AYRALVAARG DVQEVMLGYS DSNKEAGITT SQWSIHRAQR SLRDVAARHG 

       610        620        630        640        650        660 
VHLRLFHGRG GTVGRGGGPT HDAILAQPYG TLDGAIKVTE QGEVISDKYT LPALARENLE 

       670        680        690        700        710        720 
LTVAAVLQAT LLHTAPRQPA EMLERWDAAM DVVSSSAFRS YRSLVEEPDL PAYFWASTPT 

       730        740        750        760        770        780 
ELLGALNIGS RPAKRPNTGA GLSGLRAIPW VFGWTQTRQI VPGWFGVGSG LAAARAAGLA 

       790        800        810        820        830        840 
DVLAEMNRNW HFFRTFLSNV EMMLTKTDLT IARRYVETLV PKKLHPIFDK IEQEYELTKQ 

       850        860        870        880        890        900 
EVLAVTAAPA LLDNSPVLQR TLAVRDTYLE PLHHLQVALL RQYRESGAAG RAVVTAPGGR 

       910        920 
RAPNDGTALE RALLTTVNGI AAGMRNTG 

« Hide

References

[1]"Complete sequence of Micromonospora sp. L5."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G., De Hoff P.L., Hirsch A.M., Woyke T.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002399 Genomic DNA. Translation: ADU06664.1.
RefSeqYP_004080815.1. NC_014815.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADU06664; ADU06664; ML5_1124.
GeneID10056614.
KEGGmil:ML5_1124.
PATRIC45270100. VBIMicSp154089_1139.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000238647.
KOK01595.
OMAAIPWVFG.

Enzyme and pathway databases

BioCycMSP648999:GHVN-1141-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8S0H6_MICSL
AccessionPrimary (citable) accession number: E8S0H6
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 19, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)