E8RWN3 (E8RWN3_MICSL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrolipoyllysine-residue acetyltransferase EMBL ADU08747.1
EC=2.3.1.12 EMBL ADU08747.1

Gene names

Ordered Locus Names:

ML5_3231

Organism

Micromonospora sp. (strain L5) [Complete proteome] [HAMAP] EMBL ADU08747.1

Taxonomic identifier

648999 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Micromonospora

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423 Contains 1 lipoyl-binding domain. RuleBase RU000447

Ontologies

Keywords
Domain	Lipoyl RuleBase RU000447 SAAS SAAS003016
Molecular function	Acyltransferase RuleBase RU003765 EMBL ADU08747.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	dihydrolipoyllysine-residue acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E8RWN3 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 3B38113F4E949177	FASTA	425	45,289
	10 20 30 40 50 60 MSVQQFRLPD VGEGLTEAEI VTWRVAPGDP VGLNDVIVDI ETAKAVVELP SPYAGVVDRL 70 80 90 100 110 120 LAGEGQTVEV GAPIIAIRTG DDADAPDAAP AAAPPPADEP AVERTAVLVG YGVSAQARTR 130 140 150 160 170 180 RLRRATPSVR PAEPARPAHT SRPPVLTKPP LRKLAKDLGV ELADVRGSGP DGRITRQDLL 190 200 210 220 230 240 DHTTGPAPVA DHRRDERLPV RGVRKATAAA MVASAFTAPH VTEFLTVDMT GTVEFVDRLK 250 260 270 280 290 300 QDPAFQGVKV SPLLVASLAV LDAVRRYPDV NTRWDEENQE IVRFADVNLG IAAATPRGLL 310 320 330 340 350 360 VPNVKAAQNL PVRDLAVALN ELASTAREGR TRPADLSGGT ITITNIGVFG VDAGTPILNP 370 380 390 400 410 420 GEAAILCLGA LRRMPWVVDE QVVPRWTAQL SLSFDHRLVD GELGSRVLAH VGRFLEDPLW GLALR

References

[1]

"Complete sequence of Micromonospora sp. L5." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Ovchinnikova G., De Hoff P.L., Hirsch A.M., Woyke T. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: L5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002399 Genomic DNA. Translation: ADU08747.1.
RefSeq	YP_004082898.1. NC_014815.1.
3D structure databases
ProteinModelPortal	E8RWN3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADU08747; ADU08747; ML5_3231.
GeneID	10058749.
KEGG	mil:ML5_3231.
PATRIC	45274407. VBIMicSp154089_3253.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000281564.
KO	K00627.
OMA	ELVSWAV.
Enzyme and pathway databases
BioCyc	MSP648999:GHVN-3275-MONOMER.
Family and domain databases
Gene3D	3.30.559.10. 1 hit. 4.10.320.10. 1 hit.
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR011053. Single_hybrid_motif. [Graphical view]
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 1 hit. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 1 hit. PS00189. LIPOYL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E8RWN3_MICSL

Accession

Primary (citable) accession number: E8RWN3

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)