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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Asticcacaulis excentricus (strain ATCC 15261 / DSM 4724 / VKM B-1370 / CB 48)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei125UniRule annotation1
Active sitei550UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Astex_1955Imported
OrganismiAsticcacaulis excentricus (strain ATCC 15261 / DSM 4724 / VKM B-1370 / CB 48)Imported
Taxonomic identifieri573065 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeAsticcacaulis
Proteomesi
  • UP000001492 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi573065.Astex_1955.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiCOG2352. LUCA.
HOGENOMiHOG000238647.
KOiK01595.
OMAiPWVFGWT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E8RL05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDAMIDHVK QNTAMLEGFL TDAVNSFGRG TVLSKIEALR ADNADVDDLS
60 70 80 90 100
ESEAAHAARV LTCLSTLTVL SEDVANLKRV ETFPGTQEAI TLANAVQQAR
110 120 130 140 150
AKGHSQAEIE ETLNGILASP VFTAHPTEMR RASVVEREYD ITQFLSAYER
160 170 180 190 200
TTRASERKAL EEDLFRAVAL LFNTRLNRPE RITVADEIQN SLGAVRRAIL
210 220 230 240 250
PALVELYGDW NREIELEGEL PNVLKLGSWI GGDRDGHPHV DDTTMNYAFH
260 270 280 290 300
NQAKLVLDFY FQQLDKLDIE LTLSEELAPV TDALLELARK SSDTNVHRVD
310 320 330 340 350
EPYRRALTFI KTRLASTWQA ILKLPHPLAS PLAGAYETSE NFVRDLLIIR
360 370 380 390 400
DSLIEYGGKR LVGRTLKSTI QIARSCGFHL LSLDMRQNSA VHERVIAELF
410 420 430 440 450
AQSSELLDYS SLSENERVSA LVAELTNDRL LRWPFAKYSD ETRRELRIID
460 470 480 490 500
AAAEVIRTFG PDAIGAYVVS MAKSVSDILE PLVLLKQAGL VYGGPSPHTM
510 520 530 540 550
IRVSPLFETI EDLEAAPDIM KRWLGLPAMR SLMGRPAVQE VMLGYSDSNK
560 570 580 590 600
DGGYTASRWS LHKASSAIKA VCNQKGVALR LFHGRGGSVG RGGGPSFNAI
610 620 630 640 650
MAQPEGTVGG QIRVTEQGEM IARKFGNKTT AGKTLDSFSA AVFLASLPVK
660 670 680 690 700
ERDAHHIKES EAEAKYGPLM NQLCKASFDA YRALVYDDPH FLDFFRSVTP
710 720 730 740 750
ISEISDLKIG SRPASRTKSG KIEDLRAIPW VFSWSQSRMV LPGFYGFNAA
760 770 780 790 800
VKALGVDDQT LIDMCNEWDF FEVFLANMEM ALAKSDMEMA SLYAGMASDP
810 820 830 840 850
VEAQRIFATI RQEHEEMTAL AKRIRKAGTL LSTHEQLRGS IERSHALLQT
860 870 880 890
LNRMQVKLLK KRREGNKHKL VKLAMQLTVN GIASALRNTG
Length:890
Mass (Da):98,725
Last modified:April 5, 2011 - v1
Checksum:iF2F59EE11FD9D2D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002395 Genomic DNA. Translation: ADU13618.1.
RefSeqiWP_013479448.1. NC_014816.1.

Genome annotation databases

EnsemblBacteriaiADU13618; ADU13618; Astex_1955.
KEGGiaex:Astex_1955.

Similar proteinsi

Entry informationi

Entry nameiE8RL05_ASTEC
AccessioniPrimary (citable) accession number: E8RL05
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 27, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported