Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

E8RC25 (E8RC25_DESPD) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length465 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
E8RC25 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 65347506CD6252D0

FASTA46550,674
        10         20         30         40         50         60 
MNRATASSQI NTPASNYKGE CATIDGRRAI EYSPHFVMRS MHRCSFVRIY GDLSSIKESI 

        70         80         90        100        110        120 
LTADIITLKA NGALNVPANP IIPYIEGDGT GPDIWAAAQK VLDAAVAKSY GQSRKIEWLE 

       130        140        150        160        170        180 
VLAGEKAFRV TGEWLPRETI DALKKYTVSI KGPLTTPVGE GMRSLNVTLR QVLDLYACVR 

       190        200        210        220        230        240 
PVRYYQGVVS PVKEPGLVDM VIFRENTEDV YAGIEWQAGT EKANRVIDFL RNEMGASIRD 

       250        260        270        280        290        300 
NSGIGIKPIS EFGTKRLVRK AIQYALDEGR NSVTLVHKGN IMKFTEGAFR HWGYELAAEE 

       310        320        330        340        350        360 
FGESTITETA LWEQFNGAIP EGKIVIKDRI ADAMFQQILL RPSEYSVLAM PNLNGDYISD 

       370        380        390        400        410        420 
ALAAQVGGLG MAPGANIGDG VALFEATHGT APKYAGLDKV NPGSVLLSGV MLLDYIGWKE 

       430        440        450        460 
AAELIKSALE TTISKKTVTY DLARLMEGAT ELSCSAFGSA IINNM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002364 Genomic DNA. Translation: ADW16750.1.
RefSeqYP_004194041.1. NC_014972.1.

3D structure databases

ProteinModelPortalE8RC25.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADW16750; ADW16750; Despr_0574.
GeneID10173283.
KEGGdpr:Despr_0574.
PATRIC46934529. VBIDesPro114934_0605.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.

Enzyme and pathway databases

BioCycDPRO577650:GH80-584-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE8RC25_DESPD
AccessionPrimary (citable) accession number: E8RC25
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 16, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)