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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

Isop_2834

Organism
Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: InterPro
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciIPAL575540:GI5T-2877-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Isop_2834Imported
OrganismiIsosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B)Imported
Taxonomic identifieri575540 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeIsosphaera
ProteomesiUP000008631: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE8R149.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000021113.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8R149-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGIPITVAYG DGIGPEIMAA TLIVLKEAGA DLEPEVIEIG ESIYQRGVSS
60 70 80 90 100
GIEPTSWESL RRTGVFLKSP VTTPQGGGFK SLNVTIRKGL GLYANVRPCQ
110 120 130 140 150
AYAPFVRTLH PRMDLVIIRE NEEDLYAGIE HRQTDEVMQC LKLISRPGCE
160 170 180 190 200
RIVRYAFEFA RAHGRTKVTC MTKDNIMKLT DGLFHQVFDE IGRDYPELKQ
210 220 230 240 250
DHLIIDIGAA RLADTPEIFD VIVTPNLYGD ILSDIAAQVA GSVGLAGSAN
260 270 280 290 300
IGDHGAMFEA IHGSAPTIAG KNLANPSGLL QAAVMMLVHL GLGELATTIR
310 320 330 340 350
NAWLRTLEDG LHTADIAGTL TKTTVGTLEF AQAVVERLGQ RPERLKPASF
360 370 380 390 400
EADNPDPIPA PAHPPSLTRA PAPSPAAALP AYRRAPETSK TLVGVDLFLN
410 420 430 440 450
WREGSPEDLG RTLSKSATPK LTLCMITNRG VKVWPNGLPE TFCTDHWRCR
460 470 480 490
FMSERQEPID HRDILELYQR VIQSGFDVIK TENLCLFDGV PGFALGQGQ
Length:499
Mass (Da):54,375
Last modified:April 5, 2011 - v1
Checksum:i7E0177102D3923A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002353 Genomic DNA. Translation: ADV63400.1.
RefSeqiYP_004179949.1. NC_014962.1.

Genome annotation databases

EnsemblBacteriaiADV63400; ADV63400; Isop_2834.
GeneIDi10156976.
KEGGiipa:Isop_2834.
PATRICi46960370. VBIIsoPal14453_3656.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002353 Genomic DNA. Translation: ADV63400.1.
RefSeqiYP_004179949.1. NC_014962.1.

3D structure databases

ProteinModelPortaliE8R149.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADV63400; ADV63400; Isop_2834.
GeneIDi10156976.
KEGGiipa:Isop_2834.
PATRICi46960370. VBIIsoPal14453_3656.

Phylogenomic databases

HOGENOMiHOG000021113.
KOiK00031.

Enzyme and pathway databases

BioCyciIPAL575540:GI5T-2877-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 43644.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43644 / DSM 9630 / IS1BImported.

Entry informationi

Entry nameiE8R149_ISOPI
AccessioniPrimary (citable) accession number: E8R149
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.