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Protein
Submitted name:

Mechanosensitive channel MscS

Gene

HPIN_05000

Organism
Helicobacter pylori (strain India7)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciHPYL907238:GLEI-974-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Mechanosensitive channel MscSImported
Gene namesi
Ordered Locus Names:HPIN_05000Imported
OrganismiHelicobacter pylori (strain India7)Imported
Taxonomic identifieri907238 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000009059 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HW9X-ray4.14A/B/C/D/E/F/G1-272[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK03442.
OMAiSNNTACR.

Family and domain databases

InterProiIPR010920. LSM_dom.
IPR011066. MscC_channel_C.
IPR006685. MscS_channel.
IPR011014. MscS_channel_TM-2.
[Graphical view]
PfamiPF00924. MS_channel. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.
SSF82689. SSF82689. 1 hit.
SSF82861. SSF82861. 1 hit.

Sequencei

Sequence statusi: Complete.

E8QGV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEIKTLLVD FFPQAKHFGI ILIKAVIVFC IGFYFSFFLR NKTMKLLSKK
60 70 80 90 100
DEILANFVAQ VTFILILIIT TIIALSTLGV QTTSIITVLG TVGIAVALAL
110 120 130 140 150
KDYLSSIAGG IILIILHPFK KGDIIEISGL EGKVEALNFF NTSLRLHDGR
160 170 180 190 200
LAVLPNRSVA NSNIINSNNT ACRRIEWVCG VGYGSDIELV HKTIKDVIDA
210 220 230 240 250
MDKIDKNMPT FIGITDFGSS SLNFTIRVWA KIEDGIFNVR SELIERIKNA
260 270
LDANHIEIPF NKLDIAIKNQ DSSK
Length:274
Mass (Da):30,358
Last modified:April 5, 2011 - v1
Checksum:i2DE532610A8825E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002331 Genomic DNA. Translation: ADU80214.1.
RefSeqiWP_000343461.1. NC_017372.1.
YP_005782299.1. NC_017372.1.

Genome annotation databases

EnsemblBacteriaiADU80214; ADU80214; HPIN_05000.
KEGGihpn:HPIN_05000.
PATRICi45422734. VBIHelPyl171055_0997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002331 Genomic DNA. Translation: ADU80214.1.
RefSeqiWP_000343461.1. NC_017372.1.
YP_005782299.1. NC_017372.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HW9X-ray4.14A/B/C/D/E/F/G1-272[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADU80214; ADU80214; HPIN_05000.
KEGGihpn:HPIN_05000.
PATRICi45422734. VBIHelPyl171055_0997.

Phylogenomic databases

KOiK03442.
OMAiSNNTACR.

Enzyme and pathway databases

BioCyciHPYL907238:GLEI-974-MONOMER.

Family and domain databases

InterProiIPR010920. LSM_dom.
IPR011066. MscC_channel_C.
IPR006685. MscS_channel.
IPR011014. MscS_channel_TM-2.
[Graphical view]
PfamiPF00924. MS_channel. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.
SSF82689. SSF82689. 1 hit.
SSF82861. SSF82861. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of Helicobacter pylori strain India7."
    Kersulyte D., Mukhopadhyay A., Choudhury A., Nair G.B., Berg D.E.
    Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: India7Imported.
  2. "Open and shut: crystal structures of the dodecylmaltoside solubilized mechanosensitive channel of small conductance from Escherichia coli and Helicobacter pylori at 4.4 A and 4.1 A resolutions."
    Lai J.Y., Poon Y.S., Kaiser J.T., Rees D.C.
    Protein Sci. 22:502-509(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (4.14 ANGSTROMS) OF 1-272.

Entry informationi

Entry nameiE8QGV2_HELP7
AccessioniPrimary (citable) accession number: E8QGV2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 1, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.