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E8QGV2

- E8QGV2_HELP7

UniProt

E8QGV2 - E8QGV2_HELP7

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Protein
Submitted name:

Mechanosensitive channel MscS

Gene

HPIN_05000

Organism
Helicobacter pylori (strain India7)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. transmembrane transport Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciHPYL907238:GLEI-974-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Mechanosensitive channel MscSImported
Gene namesi
Ordered Locus Names:HPIN_05000Imported
OrganismiHelicobacter pylori (strain India7)Imported
Taxonomic identifieri907238 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000009059: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4HW9X-ray4.14A/B/C/D/E/F/G1-272[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK03442.
OMAiGMEKIDK.

Family and domain databases

InterProiIPR010920. LSM_dom.
IPR011066. MscC_channel_C.
IPR006685. MscS_channel.
IPR011014. MscS_channel_TM-2.
[Graphical view]
PfamiPF00924. MS_channel. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.
SSF82689. SSF82689. 1 hit.
SSF82861. SSF82861. 1 hit.

Sequencei

Sequence statusi: Complete.

E8QGV2-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MDEIKTLLVD FFPQAKHFGI ILIKAVIVFC IGFYFSFFLR NKTMKLLSKK
60 70 80 90 100
DEILANFVAQ VTFILILIIT TIIALSTLGV QTTSIITVLG TVGIAVALAL
110 120 130 140 150
KDYLSSIAGG IILIILHPFK KGDIIEISGL EGKVEALNFF NTSLRLHDGR
160 170 180 190 200
LAVLPNRSVA NSNIINSNNT ACRRIEWVCG VGYGSDIELV HKTIKDVIDA
210 220 230 240 250
MDKIDKNMPT FIGITDFGSS SLNFTIRVWA KIEDGIFNVR SELIERIKNA
260 270
LDANHIEIPF NKLDIAIKNQ DSSK
Length:274
Mass (Da):30,358
Last modified:April 5, 2011 - v1
Checksum:i2DE532610A8825E7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002331 Genomic DNA. Translation: ADU80214.1.
RefSeqiYP_005782299.1. NC_017372.1.

Genome annotation databases

EnsemblBacteriaiADU80214; ADU80214; HPIN_05000.
GeneIDi12362426.
KEGGihpn:HPIN_05000.
PATRICi45422734. VBIHelPyl171055_0997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002331 Genomic DNA. Translation: ADU80214.1 .
RefSeqi YP_005782299.1. NC_017372.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4HW9 X-ray 4.14 A/B/C/D/E/F/G 1-272 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADU80214 ; ADU80214 ; HPIN_05000 .
GeneIDi 12362426.
KEGGi hpn:HPIN_05000.
PATRICi 45422734. VBIHelPyl171055_0997.

Phylogenomic databases

KOi K03442.
OMAi GMEKIDK.

Enzyme and pathway databases

BioCyci HPYL907238:GLEI-974-MONOMER.

Family and domain databases

InterProi IPR010920. LSM_dom.
IPR011066. MscC_channel_C.
IPR006685. MscS_channel.
IPR011014. MscS_channel_TM-2.
[Graphical view ]
Pfami PF00924. MS_channel. 1 hit.
[Graphical view ]
SUPFAMi SSF50182. SSF50182. 1 hit.
SSF82689. SSF82689. 1 hit.
SSF82861. SSF82861. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of Helicobacter pylori strain India7."
    Kersulyte D., Mukhopadhyay A., Choudhury A., Nair G.B., Berg D.E.
    Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: India7Imported.
  2. "Open and shut: crystal structures of the dodecylmaltoside solubilized mechanosensitive channel of small conductance from Escherichia coli and Helicobacter pylori at 4.4 A and 4.1 A resolutions."
    Lai J.Y., Poon Y.S., Kaiser J.T., Rees D.C.
    Protein Sci. 22:502-509(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (4.14 ANGSTROMS) OF 1-272.

Entry informationi

Entry nameiE8QGV2_HELP7
AccessioniPrimary (citable) accession number: E8QGV2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteomeImported

External Data

Dasty 3