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Protein

Probable transaldolase

Gene

tal

Organism
Thermus scotoductus (strain ATCC 700910 / SA-01)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotationSAAS annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei92 – 921Schiff-base intermediate with substrateUniRule annotation

GO - Molecular functioni

  1. sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationSAAS annotation

Keywords - Biological processi

Pentose shuntUniRule annotationSAAS annotation

Keywords - Ligandi

Schiff baseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciTSCO743525:GCD4-1555-MONOMER.
UniPathwayiUPA00115; UER00414.
UPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:TSC_c15580Imported
OrganismiThermus scotoductus (strain ATCC 700910 / SA-01)Imported
Taxonomic identifieri743525 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000008087: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3B subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000226073.
KOiK00616.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00494. Transaldolase_3b.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004731. Transaldolase_3A/3B.
IPR022999. Transaldolase_3B.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00875. fsa_talC_mipB. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8PKM2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MELYLDTANL EEIREIAAWG VLSGVTTNPT LVAKEYAGRG TKLTEEVLFA
60 70 80 90 100
HLRAICEVAK GPVSAEVTAL EAGAMVEEGL RLAAIHPHIV VKLPTTEEGL
110 120 130 140 150
KACKRLSTQG VKVNMTLIFS ANQALLAARA GAAYVSPFLG RVDDISWDGG
160 170 180 190 200
ELLREIVELI QVQNLPVKVI AASIRHPRHV TEAALLGADI ATMPYTVFKQ
210 220
LLKHPLTDIG LRRFMEDWEK VKP
Length:223
Mass (Da):24,326
Last modified:April 5, 2011 - v1
Checksum:i82F54DA407C79E56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001962 Genomic DNA. Translation: ADW22174.1.
RefSeqiWP_015717443.1. NC_014974.1.
YP_004202723.1. NC_014974.1.

Genome annotation databases

EnsemblBacteriaiADW22174; ADW22174; TSC_c15580.
GeneIDi10177679.
KEGGitsc:TSC_c15580.
PATRICi47045950. VBITheSco147128_1505.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001962 Genomic DNA. Translation: ADW22174.1.
RefSeqiWP_015717443.1. NC_014974.1.
YP_004202723.1. NC_014974.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADW22174; ADW22174; TSC_c15580.
GeneIDi10177679.
KEGGitsc:TSC_c15580.
PATRICi47045950. VBITheSco147128_1505.

Phylogenomic databases

HOGENOMiHOG000226073.
KOiK00616.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.
UPA00115; UER00414.
BioCyciTSCO743525:GCD4-1555-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00494. Transaldolase_3b.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004731. Transaldolase_3A/3B.
IPR022999. Transaldolase_3B.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00875. fsa_talC_mipB. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Thermus scotoductus SA-01."
    Gounder K., Liesegang H., Brzuszkiewicz E., Wollherr A., Daniel R., Gottschalk G., van Heerden E., Litthauer D.
    Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700910 / SA-01Imported.

Entry informationi

Entry nameiE8PKM2_THESS
AccessioniPrimary (citable) accession number: E8PKM2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.