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E8PJW4

- E8PJW4_THESS

UniProt

E8PJW4 - E8PJW4_THESS

Protein

Elongation factor Tu

Gene

tuf1

Organism
Thermus scotoductus (strain ATCC 700910 / SA-01)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi82 – 865GTPUniRule annotation
    Nucleotide bindingi137 – 1404GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciTSCO743525:GCD4-174-MONOMER.
    TSCO743525:GCD4-2243-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf1Imported
    Synonyms:tufUniRule annotation, tuf2Imported
    Ordered Locus Names:TSC_c01740Imported, TSC_c22460Imported
    OrganismiThermus scotoductus (strain ATCC 700910 / SA-01)Imported
    Taxonomic identifieri743525 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000008087: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E8PJW4-1 [UniParc]FASTAAdd to Basket

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    MAKGEFIRTK PHVNVGTIGH VDHGKTTLTA ALTFVAAAEN PNVEVKDYGE    50
    IDKAPEERAR GITINTAHVE YETAKRHYSH VDCPGHADYI KNMITGAAQM 100
    DGAILVVSAA DGPMPQTREH ILLARQVGVP YIVVFMNKVD MVDDPELLDL 150
    VEMEVRDLLN QYEFPGDEVP VIRGSALLAL EQMHKNPQTK RGENEWVDKI 200
    WELLDAIDEY IPTPVRDVDK PFLMPVEDVF TITGRGTVAT GRIERGKVKV 250
    GDEVEIVGLA PETRKTVVTG VEMHRKTLQE GIAGDNVGLL LRGVSREEVE 300
    RGQVLAKPGS ITPHTKFEAS VYILKKEEGG RHTGFFSGYR PQFYFRTTDV 350
    TGVVELPSGV EMVMPGDNVT FTVELIKPVA LEEGLRFAIR EGGRTVGAGV 400
    VTKILE 406
    Length:406
    Mass (Da):44,729
    Last modified:April 5, 2011 - v1
    Checksum:i5FEEBC97E67DDDE9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001962 Genomic DNA. Translation: ADW20816.1.
    CP001962 Genomic DNA. Translation: ADW22849.1.
    RefSeqiWP_015716104.1. NC_014974.1.
    YP_004201365.1. NC_014974.1.
    YP_004203398.1. NC_014974.1.

    Genome annotation databases

    EnsemblBacteriaiADW20816; ADW20816; TSC_c01740.
    ADW22849; ADW22849; TSC_c22460.
    GeneIDi10176295.
    10178367.
    KEGGitsc:TSC_c01740.
    tsc:TSC_c22460.
    PATRICi47043192. VBITheSco147128_0162.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001962 Genomic DNA. Translation: ADW20816.1 .
    CP001962 Genomic DNA. Translation: ADW22849.1 .
    RefSeqi WP_015716104.1. NC_014974.1.
    YP_004201365.1. NC_014974.1.
    YP_004203398.1. NC_014974.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADW20816 ; ADW20816 ; TSC_c01740 .
    ADW22849 ; ADW22849 ; TSC_c22460 .
    GeneIDi 10176295.
    10178367.
    KEGGi tsc:TSC_c01740.
    tsc:TSC_c22460.
    PATRICi 47043192. VBITheSco147128_0162.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.

    Enzyme and pathway databases

    BioCyci TSCO743525:GCD4-174-MONOMER.
    TSCO743525:GCD4-2243-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Thermus scotoductus SA-01."
      Gounder K., Liesegang H., Brzuszkiewicz E., Wollherr A., Daniel R., Gottschalk G., van Heerden E., Litthauer D.
      Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700910 / SA-01Imported and SA-01.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: SA-01Imported.

    Entry informationi

    Entry nameiE8PJW4_THESS
    AccessioniPrimary (citable) accession number: E8PJW4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3