Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Thermus scotoductus (strain ATCC 700910 / SA-01)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei148 – 1481UniRule annotation
Active sitei534 – 5341UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTSCO743525:GCD4-1392-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:TSC_c13950Imported
OrganismiThermus scotoductus (strain ATCC 700910 / SA-01)Imported
Taxonomic identifieri743525 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000008087: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238648.
KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8PJQ9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKPAKEDTFD LLRAEVDLLG RLLGEAIRAV SGERFFALVE EVRLLSKARR
60 70 80 90 100
QGDEGARATL LKRVEGLSLE EAEALVRAFT HYFHLVNLAE ERHRVRVNRL
110 120 130 140 150
RAQAETPESP RPEGFLALAR ALKERGLSLE EVEAHLNRLE LWLTFTAHPT
160 170 180 190 200
ETRRRTLRHH LEKLQEELEA QDRSRLAARV ALLYATEEVR KARPTVEDEI
210 220 230 240 250
KGGLYYLPTT LWQAVPRVVE GLEAALEKVY GRRPRLKSPV RFRSWIGGDR
260 270 280 290 300
DGNPFVTPEV TAFAARYARQ VARERFLLEL ENLVRDLSLS ETKVPVPRGV
310 320 330 340 350
REGGEGTERF PGEPYRRFFA RLYTRLEKGE ASTEELLRAL RVAEEGLASV
360 370 380 390 400
GLEQVAASFL RPLEARLFAF GLELAPLDLR EESGKLLEAA AELLRVGGGH
410 420 430 440 450
PDFLSLPPEA QEALLTEELR SARPLLPVGH EPQGEALRVA LGAFRAWRDK
460 470 480 490 500
GAHVVSMTHH PGDLLAVFLL AREVGLYRPG APLPLDVVPL FETLEDLHRA
510 520 530 540 550
PEVLTRLLQN PVFLAHARGR GGVEIMIGYS DSNKDAGFLA ANLALYEAQE
560 570 580 590 600
ALAKVGQSFG LPVFFFHGRG TSTARGGGPA GRAIASLPPR SVGHRIRLTE
610 620 630 640 650
QGEALADRYS HPELAVRHLE QLLFHFAQAA LGEGVEPRPE WREALWQAGE
660 670 680 690 700
ESMRRYRALL AQEGFFPFFE AFTPIREIGE LPIASRPVYR HGRVREIRDL
710 720 730 740 750
RAIPWVMAWT QVRLLLPGWY GLTALEALPL DLLRRMYREW PFFATTLENA
760 770 780 790 800
AMALAKADLG VAELYLRLVP EKLHSLFHGL AQEYQKTVTL LESIFQAPLL
810 820 830 840 850
HNQRTLERQI ALRNPYVDPI NFVQVELLRR YRAPGGREDE ALKKALLLSI
860
LGVAAGLRNA G
Length:861
Mass (Da):96,837
Last modified:April 5, 2011 - v1
Checksum:i01C5154A961CD6C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001962 Genomic DNA. Translation: ADW22014.1.
RefSeqiWP_015717285.1. NC_014974.1.
YP_004202563.1. NC_014974.1.

Genome annotation databases

EnsemblBacteriaiADW22014; ADW22014; TSC_c13950.
GeneIDi10177516.
KEGGitsc:TSC_c13950.
PATRICi47045623. VBITheSco147128_1347.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001962 Genomic DNA. Translation: ADW22014.1.
RefSeqiWP_015717285.1. NC_014974.1.
YP_004202563.1. NC_014974.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADW22014; ADW22014; TSC_c13950.
GeneIDi10177516.
KEGGitsc:TSC_c13950.
PATRICi47045623. VBITheSco147128_1347.

Phylogenomic databases

HOGENOMiHOG000238648.
KOiK01595.

Enzyme and pathway databases

BioCyciTSCO743525:GCD4-1392-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Thermus scotoductus SA-01."
    Gounder K., Liesegang H., Brzuszkiewicz E., Wollherr A., Daniel R., Gottschalk G., van Heerden E., Litthauer D.
    Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700910 / SA-01Imported.

Entry informationi

Entry nameiE8PJQ9_THESS
AccessioniPrimary (citable) accession number: E8PJQ9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.