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E8P5H1

- E8P5H1_YERPH

UniProt

E8P5H1 - E8P5H1_YERPH

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, YPC_0287
Organism
Yersinia pestis bv. Medievalis (strain Harbin 35)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371 By similarityUniRule annotation
Active sitei545 – 5451 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciYPES547048:GLMW-278-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:YPC_0287Imported
OrganismiYersinia pestis bv. Medievalis (strain Harbin 35)Imported
Taxonomic identifieri547048 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000008088: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiE8P5H1.

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE8P5H1.
SMRiE8P5H1. Positions 4-878.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiELSTISC.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8P5H1-1 [UniParc]FASTAAdd to Basket

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MNEQYSAMRS NVSMLGTLLG DTIKEALGEH ILDRVETIRK LSKSSRAGNE    50
ASRQELLTTL QNLSNDELLP VARAFSQFLN LTNTAEQYHS ISPHGEAASN 100
PEALAQLFTR LKDKKLSDQD MRSAVDDLSI ELVLTAHPTE ITRRTLIHKL 150
VEVNTCLSQL DHNDLADYER NKIMRRLRQL VAQSWHTDEI RKLRPSPVDE 200
AKWGFAVVEN SLWEGVPAFL REFNEQLENS LDYRLPVEAV PIRFTSWMGG 250
DRDGNPNVTA EITRHVLLLS RWKATDLFLR DIQVLVSELS MSECTPELRE 300
LAGGEEVLEP YRQLMKNVRT QLTNTQAYLE ARLKGERVLP PHDLLVSNDQ 350
LWEPLYACYQ SLKACGMEII ANGQLLDTLR RVRCFGVPLV RIDVRQESTR 400
HTDAIAELTR YLGLGDYESW SESDKQAFLV RELNSKRPLV PLKWEPSAET 450
QEVLETCRVI AEAPQGSIAA YVISMAKVPS DVLAVHLLLK EAGCPFTLPV 500
APLFETLDDL NNADDVMTQL LGIDWYRGLI QGKQMVMIGY SDSAKDAGVM 550
AASWAQYRAQ DALIKTCEKA GITLTLFHGR GGSIGRGGAP AHAALLSQPP 600
GSLKGGLRVT EQGEMIRFKF GLPEVTISSL ALYAGAILEA NLLPPPEPKK 650
EWIEVMDLLS DASCDMYRSY VRENPEFVRY FRAATPELEL GKLPLGSRPA 700
KRRPDGGVES LRAIPWIFAW TQNRLMLPAW LGAGAGLQRA IDAGKQDVLA 750
TMCRDWPFFS TRIGMLEMVF AKADLWLAEY YDQRLVDKSL WPLGQQLRDQ 800
LAADIKVVLA IANDDHLMAD LPWIAESIAL RNVYTDPLNV LQAELLHRSR 850
QQEHPDACVE QALMVTIAGV AAGMRNTG 878
Length:878
Mass (Da):98,324
Last modified:April 5, 2011 - v1
Checksum:iF57CE8ABD26287B4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001608 Genomic DNA. Translation: ADV97047.1.
RefSeqiYP_005622334.1. NC_017265.1.

Genome annotation databases

EnsemblBacteriaiADV97047; ADV97047; YPC_0287.
GeneIDi12279417.
KEGGiyph:YPC_0287.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001608 Genomic DNA. Translation: ADV97047.1 .
RefSeqi YP_005622334.1. NC_017265.1.

3D structure databases

ProteinModelPortali E8P5H1.
SMRi E8P5H1. Positions 4-878.
ModBasei Search...

Proteomic databases

PRIDEi E8P5H1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADV97047 ; ADV97047 ; YPC_0287 .
GeneIDi 12279417.
KEGGi yph:YPC_0287.

Phylogenomic databases

KOi K01595.
OMAi ELSTISC.

Enzyme and pathway databases

BioCyci YPES547048:GLMW-278-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Yersinia pestis Harbin 35, complete genome."
    Plunkett G.III., Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Han C.S., Bruce D.C., Detter J.C., Tapia R., Brettin T.S., Mane S.P., Sobral B.W.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Harbin 35Imported.

Entry informationi

Entry nameiE8P5H1_YERPH
AccessioniPrimary (citable) accession number: E8P5H1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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