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E8ND12

- E8ND12_MICTS

UniProt

E8ND12 - E8ND12_MICTS

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Protein
Submitted name:

Monomeric isocitrate dehydrogenase

Gene
MTES_0687
Organism
Microbacterium testaceum (strain StLB037)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451Substrate By similarityUniRule annotation
Sitei255 – 2551Critical for catalysis By similarityUniRule annotation
Metal bindingi348 – 3481Magnesium or manganese By similarity
Sitei418 – 4181Critical for catalysis By similarityUniRule annotation
Binding sitei545 – 5451Substrate By similarityUniRule annotation
Metal bindingi546 – 5461Magnesium or manganese By similarity
Metal bindingi550 – 5501Magnesium or manganese By similarity

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Monomeric isocitrate dehydrogenaseImported
Gene namesi
Ordered Locus Names:MTES_0687Imported
OrganismiMicrobacterium testaceum (strain StLB037)Imported
Taxonomic identifieri979556 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeMicrobacterium
ProteomesiUP000008975: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE8ND12.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate binding By similarityUniRule annotation

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

E8ND12-1 [UniParc]FASTAAdd to Basket

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MPDSTIIYTY TDEAPALATA SFLPIVQAVT KQAGVDVETR DISLAGRILA    50
AFPQRLTPEQ QVGDALAELG GLATLPEANI IKLPNISASI PQLKAAIAEL 100
QAQGYDIPDY PDEASTVEDK DVRARYDRIK GSAVNPVLRE GNSDRRAPLA 150
VKNYAKKHPH RNKAFAEGSK TRVATMGHDD FFSNEKSVVI ADDDVLTIQH 200
VAADGTTTTL KEGLKVLQGE IVDATFLSAA ALDAFLADTL EQAKADDVLY 250
SVHLKATMMK VSDPIIFGHV VKAFFADVFD RHGDALAAAG LTPNDGLGSI 300
LAGLSNVEGG DGIASEIRDA LASGPRLSYV NSDKGITNLH VPSDVIVDAS 350
MPALVRNGGK LWGVDGGEDD TLAVIPDSSY AGVYQATIED VIANGPLDPA 400
TIGSVPNVGL MAQAAEEYGS HDKTFEIAAP GRVQVVASNG DVLLEHEVGA 450
GDIWRATQTK DVAVRDWVKL AVTRARATGV PAVFWLDETR AHDRNLIAKV 500
NEYLADHDTE GLTIEILAPA EATRYSLERI RRGEDTISVT GNVLRDYLTD 550
LFPILEVGTS AKMLSIVPLL AGGGLFETGA GGSAPKHVQQ LVEEDYLRWD 600
SLGEFFALAA SLEHLADTTG NKRARVLAQT LDAATGTFLE NDKSPGRALG 650
TIDNRGSHFY LALYWAQELA KQTTDADLAA VFGPVAEKLA AEEQTIVAEL 700
NAVQGHHAEI GGYYRPNTEL VEKVMRPSAT LNAVVDALR 739
Length:739
Mass (Da):78,823
Last modified:April 5, 2011 - v1
Checksum:iAE64684BF8D2BAE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012052 Genomic DNA. Translation: BAJ73651.1.
RefSeqiWP_013583778.1. NC_015125.1.
YP_004223531.1. NC_015125.1.

Genome annotation databases

EnsemblBacteriaiBAJ73651; BAJ73651; MTES_0687.
GeneIDi10217629.
KEGGimts:MTES_0687.
PATRICi46968441. VBIMicTes185510_0677.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012052 Genomic DNA. Translation: BAJ73651.1 .
RefSeqi WP_013583778.1. NC_015125.1.
YP_004223531.1. NC_015125.1.

3D structure databases

ProteinModelPortali E8ND12.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAJ73651 ; BAJ73651 ; MTES_0687 .
GeneIDi 10217629.
KEGGi mts:MTES_0687.
PATRICi 46968441. VBIMicTes185510_0677.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of Microbacterium testaceum StLB037, an N-acylhomoserine lactone-degrading bacterium isolated from potato leaves."
    Morohoshi T., Wang W.-Z., Someya N., Ikeda T.
    J. Bacteriol. 193:2072-2073(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: StLB037Imported.
  2. "Genome sequence of Microbacterium testaceum StLB037."
    Morohoshi T., Wang W.Z., Someya N., Ikeda T.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: StLB037.

Entry informationi

Entry nameiE8ND12_MICTS
AccessioniPrimary (citable) accession number: E8ND12
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 3, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi