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E8ND12

- E8ND12_MICTS

UniProt

E8ND12 - E8ND12_MICTS

Protein
Submitted name:

Monomeric isocitrate dehydrogenase

Gene

MTES_0687

Organism
Microbacterium testaceum (strain StLB037)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei145 – 1451Substrate
    Sitei255 – 2551Critical for catalysisUniRule annotation
    Metal bindingi348 – 3481Magnesium or manganeseUniRule annotation
    Sitei418 – 4181Critical for catalysisUniRule annotation
    Binding sitei545 – 5451SubstrateUniRule annotation
    Metal bindingi546 – 5461Magnesium or manganeseUniRule annotation
    Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Monomeric isocitrate dehydrogenaseImported
    Gene namesi
    Ordered Locus Names:MTES_0687Imported
    OrganismiMicrobacterium testaceum (strain StLB037)Imported
    Taxonomic identifieri979556 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeMicrobacterium
    ProteomesiUP000008975: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE8ND12.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni132 – 1398Substrate binding

    Phylogenomic databases

    HOGENOMiHOG000240860.
    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E8ND12-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPDSTIIYTY TDEAPALATA SFLPIVQAVT KQAGVDVETR DISLAGRILA    50
    AFPQRLTPEQ QVGDALAELG GLATLPEANI IKLPNISASI PQLKAAIAEL 100
    QAQGYDIPDY PDEASTVEDK DVRARYDRIK GSAVNPVLRE GNSDRRAPLA 150
    VKNYAKKHPH RNKAFAEGSK TRVATMGHDD FFSNEKSVVI ADDDVLTIQH 200
    VAADGTTTTL KEGLKVLQGE IVDATFLSAA ALDAFLADTL EQAKADDVLY 250
    SVHLKATMMK VSDPIIFGHV VKAFFADVFD RHGDALAAAG LTPNDGLGSI 300
    LAGLSNVEGG DGIASEIRDA LASGPRLSYV NSDKGITNLH VPSDVIVDAS 350
    MPALVRNGGK LWGVDGGEDD TLAVIPDSSY AGVYQATIED VIANGPLDPA 400
    TIGSVPNVGL MAQAAEEYGS HDKTFEIAAP GRVQVVASNG DVLLEHEVGA 450
    GDIWRATQTK DVAVRDWVKL AVTRARATGV PAVFWLDETR AHDRNLIAKV 500
    NEYLADHDTE GLTIEILAPA EATRYSLERI RRGEDTISVT GNVLRDYLTD 550
    LFPILEVGTS AKMLSIVPLL AGGGLFETGA GGSAPKHVQQ LVEEDYLRWD 600
    SLGEFFALAA SLEHLADTTG NKRARVLAQT LDAATGTFLE NDKSPGRALG 650
    TIDNRGSHFY LALYWAQELA KQTTDADLAA VFGPVAEKLA AEEQTIVAEL 700
    NAVQGHHAEI GGYYRPNTEL VEKVMRPSAT LNAVVDALR 739
    Length:739
    Mass (Da):78,823
    Last modified:April 5, 2011 - v1
    Checksum:iAE64684BF8D2BAE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012052 Genomic DNA. Translation: BAJ73651.1.
    RefSeqiWP_013583778.1. NC_015125.1.
    YP_004223531.1. NC_015125.1.

    Genome annotation databases

    EnsemblBacteriaiBAJ73651; BAJ73651; MTES_0687.
    GeneIDi10217629.
    KEGGimts:MTES_0687.
    PATRICi46968441. VBIMicTes185510_0677.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012052 Genomic DNA. Translation: BAJ73651.1 .
    RefSeqi WP_013583778.1. NC_015125.1.
    YP_004223531.1. NC_015125.1.

    3D structure databases

    ProteinModelPortali E8ND12.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAJ73651 ; BAJ73651 ; MTES_0687 .
    GeneIDi 10217629.
    KEGGi mts:MTES_0687.
    PATRICi 46968441. VBIMicTes185510_0677.

    Phylogenomic databases

    HOGENOMi HOG000240860.
    KOi K00031.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Microbacterium testaceum StLB037, an N-acylhomoserine lactone-degrading bacterium isolated from potato leaves."
      Morohoshi T., Wang W.Z., Someya N., Ikeda T.
      J. Bacteriol. 193:2072-2073(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: StLB037Imported.
    2. "Genome sequence of Microbacterium testaceum StLB037."
      Morohoshi T., Wang W.Z., Someya N., Ikeda T.
      Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: StLB037.

    Entry informationi

    Entry nameiE8ND12_MICTS
    AccessioniPrimary (citable) accession number: E8ND12
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3