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E8ND12

- E8ND12_MICTS

UniProt

E8ND12 - E8ND12_MICTS

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Protein
Submitted name:

Monomeric isocitrate dehydrogenase

Gene

MTES_0687

Organism
Microbacterium testaceum (strain StLB037)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei145 – 1451Substrate
Sitei255 – 2551Critical for catalysisUniRule annotation
Metal bindingi348 – 3481Magnesium or manganeseUniRule annotation
Sitei418 – 4181Critical for catalysisUniRule annotation
Binding sitei545 – 5451SubstrateUniRule annotation
Metal bindingi546 – 5461Magnesium or manganeseUniRule annotation
Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Monomeric isocitrate dehydrogenaseImported
Gene namesi
Ordered Locus Names:MTES_0687Imported
OrganismiMicrobacterium testaceum (strain StLB037)Imported
Taxonomic identifieri979556 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeMicrobacterium
ProteomesiUP000008975: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE8ND12.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni132 – 1398Substrate binding

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

E8ND12-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPDSTIIYTY TDEAPALATA SFLPIVQAVT KQAGVDVETR DISLAGRILA
60 70 80 90 100
AFPQRLTPEQ QVGDALAELG GLATLPEANI IKLPNISASI PQLKAAIAEL
110 120 130 140 150
QAQGYDIPDY PDEASTVEDK DVRARYDRIK GSAVNPVLRE GNSDRRAPLA
160 170 180 190 200
VKNYAKKHPH RNKAFAEGSK TRVATMGHDD FFSNEKSVVI ADDDVLTIQH
210 220 230 240 250
VAADGTTTTL KEGLKVLQGE IVDATFLSAA ALDAFLADTL EQAKADDVLY
260 270 280 290 300
SVHLKATMMK VSDPIIFGHV VKAFFADVFD RHGDALAAAG LTPNDGLGSI
310 320 330 340 350
LAGLSNVEGG DGIASEIRDA LASGPRLSYV NSDKGITNLH VPSDVIVDAS
360 370 380 390 400
MPALVRNGGK LWGVDGGEDD TLAVIPDSSY AGVYQATIED VIANGPLDPA
410 420 430 440 450
TIGSVPNVGL MAQAAEEYGS HDKTFEIAAP GRVQVVASNG DVLLEHEVGA
460 470 480 490 500
GDIWRATQTK DVAVRDWVKL AVTRARATGV PAVFWLDETR AHDRNLIAKV
510 520 530 540 550
NEYLADHDTE GLTIEILAPA EATRYSLERI RRGEDTISVT GNVLRDYLTD
560 570 580 590 600
LFPILEVGTS AKMLSIVPLL AGGGLFETGA GGSAPKHVQQ LVEEDYLRWD
610 620 630 640 650
SLGEFFALAA SLEHLADTTG NKRARVLAQT LDAATGTFLE NDKSPGRALG
660 670 680 690 700
TIDNRGSHFY LALYWAQELA KQTTDADLAA VFGPVAEKLA AEEQTIVAEL
710 720 730
NAVQGHHAEI GGYYRPNTEL VEKVMRPSAT LNAVVDALR
Length:739
Mass (Da):78,823
Last modified:April 5, 2011 - v1
Checksum:iAE64684BF8D2BAE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012052 Genomic DNA. Translation: BAJ73651.1.
RefSeqiWP_013583778.1. NC_015125.1.
YP_004223531.1. NC_015125.1.

Genome annotation databases

EnsemblBacteriaiBAJ73651; BAJ73651; MTES_0687.
GeneIDi10217629.
KEGGimts:MTES_0687.
PATRICi46968441. VBIMicTes185510_0677.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012052 Genomic DNA. Translation: BAJ73651.1 .
RefSeqi WP_013583778.1. NC_015125.1.
YP_004223531.1. NC_015125.1.

3D structure databases

ProteinModelPortali E8ND12.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAJ73651 ; BAJ73651 ; MTES_0687 .
GeneIDi 10217629.
KEGGi mts:MTES_0687.
PATRICi 46968441. VBIMicTes185510_0677.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of Microbacterium testaceum StLB037, an N-acylhomoserine lactone-degrading bacterium isolated from potato leaves."
    Morohoshi T., Wang W.Z., Someya N., Ikeda T.
    J. Bacteriol. 193:2072-2073(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: StLB037Imported.
  2. "Genome sequence of Microbacterium testaceum StLB037."
    Morohoshi T., Wang W.Z., Someya N., Ikeda T.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: StLB037.

Entry informationi

Entry nameiE8ND12_MICTS
AccessioniPrimary (citable) accession number: E8ND12
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3