Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA ligase

Gene

MTES_2901

Organism
Microbacterium testaceum (strain StLB037)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMTES979556:GJFH-4351-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:MTES_2901Imported
OrganismiMicrobacterium testaceum (strain StLB037)Imported
Taxonomic identifieri979556 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrobacteriaceaeMicrobacterium
ProteomesiUP000008975: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK01971.
OMAiNDIACIV.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8NA35-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLFGDIETAL AAVTSTRSRL AKVDALAALL RELEPDEIGP AVGLLTAAPR
60 70 80 90 100
QGRLGVGWRT LASRGGAHVP APALTIGEID EAFSRLVEVG GTGSAAVRTA
110 120 130 140 150
LLDELASRAT ASEWQLLIRI MTGELRTGAL EGVLLDAIAR AADRDGAAVR
160 170 180 190 200
RAAMLSGDLG ETAVLALTGT IDDLTAVGLV VGRGVQPMLA STAATVAEAL
210 220 230 240 250
DAAGRASVEY KLDGARVQVH RHGDEVRVFT RTLADVTHRV PEIVEVARSL
260 270 280 290 300
PVDDVILDGE TLSLDEDGAP RPFQETMARF GAETAREIAL RPWFFDILHV
310 320 330 340 350
DGRDLIDEPL AARLDELERV AGEYRIPALM TDDPEAADAF ARAALQAGHE
360 370 380 390 400
GVMVKGLDAA YSAGRRGKSW LKVKPVHTFD LVVLGVERGS GRRADWLSNL
410 420 430 440 450
HLGARDPDGV FGEPGGFVMV GKTFKGLTDE LLRWQTAHFA ERATGEVPGG
460 470 480 490 500
IRVVPDTVVE IAIDGVQRSV RYPGGVALRF ARVKAYRSDK PASEADTIAT
510 520
LRAMLPGGGV GAAADDPSGG LDERTIS
Length:527
Mass (Da):55,704
Last modified:April 5, 2011 - v1
Checksum:iDAE3B22803535E73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012052 Genomic DNA. Translation: BAJ75865.1.
RefSeqiWP_013585990.1. NC_015125.1.
YP_004225745.1. NC_015125.1.

Genome annotation databases

EnsemblBacteriaiBAJ75865; BAJ75865; MTES_2901.
GeneIDi10219668.
KEGGimts:MTES_2901.
PATRICi46972914. VBIMicTes185510_2881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012052 Genomic DNA. Translation: BAJ75865.1.
RefSeqiWP_013585990.1. NC_015125.1.
YP_004225745.1. NC_015125.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAJ75865; BAJ75865; MTES_2901.
GeneIDi10219668.
KEGGimts:MTES_2901.
PATRICi46972914. VBIMicTes185510_2881.

Phylogenomic databases

HOGENOMiHOG000036008.
KOiK01971.
OMAiNDIACIV.

Enzyme and pathway databases

BioCyciMTES979556:GJFH-4351-MONOMER.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of Microbacterium testaceum StLB037, an N-acylhomoserine lactone-degrading bacterium isolated from potato leaves."
    Morohoshi T., Wang W.Z., Someya N., Ikeda T.
    J. Bacteriol. 193:2072-2073(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: StLB037Imported.
  2. "Genome sequence of Microbacterium testaceum StLB037."
    Morohoshi T., Wang W.Z., Someya N., Ikeda T.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: StLB037.

Entry informationi

Entry nameiE8NA35_MICTS
AccessioniPrimary (citable) accession number: E8NA35
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.