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E8N1N6

- E8N1N6_ANATU

UniProt

E8N1N6 - E8N1N6_ANATU

Protein
Submitted name:

Putative D-alanine--D-alanine ligase

Gene

ANT_06070

Organism
Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciATHE926569:GH0F-618-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
    Gene namesi
    Ordered Locus Names:ANT_06070Imported
    OrganismiAnaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)Imported
    Taxonomic identifieri926569 [NCBI]
    Taxonomic lineageiBacteriaChloroflexiAnaerolineaeAnaerolinealesAnaerolineaceaeAnaerolinea
    ProteomesiUP000008922: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    KOiK01921.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    PS00844. DALA_DALA_LIGASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E8N1N6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDTTIFIQEE LDPDPEKPPS SRPRPARPWR VAVIANVKGE TALPIQAPPD    50
    AGAEFDRKET IEAIQSAIES DGHTTRFLSA DHTLLDSLRE YQPDICFNIA 100
    EGIIGDAREA QVPALLEMLG IPYTASRVLA NALGLDKTMT KRIWRNLGIP 150
    TASFQEFITG DEPLEADLSF PLFVKPAREG TGMGMDEGSI VYNENQLRRR 200
    VKWVIEAYHQ PALVETYLPG REFTVGVLGR ADARRWSPKP HLYRADGFHR 250
    FPILEVDNSN TVTPGVYGYA AKTLHPGEEG VPGFICPAQV EPDLAEKLWT 300
    LAIRAHNAIG ALDVSRVDVR LDAHGNPRLL EINTLPGLTP GFSDLCVIAQ 350
    AEGLSYRDLI LEILYLGASR WGLLEEAPQA IHVPLQAHHH TFQPAPMIFK 400
    Length:400
    Mass (Da):44,278
    Last modified:April 5, 2011 - v1
    Checksum:iFAF8BA7AD59EBA50
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012029 Genomic DNA. Translation: BAJ62641.1.
    RefSeqiWP_013559036.1. NC_014960.1.
    YP_004173241.1. NC_014960.1.

    Genome annotation databases

    EnsemblBacteriaiBAJ62641; BAJ62641; ANT_06070.
    GeneIDi10172320.
    KEGGiatm:ANT_06070.
    PATRICi46852904. VBIAnaThe181647_0635.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012029 Genomic DNA. Translation: BAJ62641.1 .
    RefSeqi WP_013559036.1. NC_014960.1.
    YP_004173241.1. NC_014960.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAJ62641 ; BAJ62641 ; ANT_06070 .
    GeneIDi 10172320.
    KEGGi atm:ANT_06070.
    PATRICi 46852904. VBIAnaThe181647_0635.

    Phylogenomic databases

    KOi K01921.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci ATHE926569:GH0F-618-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    PS00844. DALA_DALA_LIGASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Anaerolinea thermophila UNI-1."
      Narita-Yamada S., Kishi E., Watanabe Y., Takasaki K., Ankai A., Oguchi A., Fukui S., Takahashi M., Yashiro I., Hosoyama A., Sekiguchi Y., Hanada S., Fujita N.
      Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1Imported.

    Entry informationi

    Entry nameiE8N1N6_ANATU
    AccessioniPrimary (citable) accession number: E8N1N6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3