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E8N1N6

- E8N1N6_ANATU

UniProt

E8N1N6 - E8N1N6_ANATU

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Protein
Submitted name:

Putative D-alanine--D-alanine ligase

Gene

ANT_06070

Organism
Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Binds 2 magnesium or manganese ions per subunit.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  3. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciATHE926569:GH0F-618-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative D-alanine--D-alanine ligaseImported (EC:6.3.2.4Imported)
Gene namesi
Ordered Locus Names:ANT_06070Imported
OrganismiAnaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)Imported
Taxonomic identifieri926569 [NCBI]
Taxonomic lineageiBacteriaChloroflexiAnaerolineaeAnaerolinealesAnaerolineaceaeAnaerolinea
ProteomesiUP000008922: Chromosome

Subcellular locationi

Cytoplasm SAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

KOiK01921.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E8N1N6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDTTIFIQEE LDPDPEKPPS SRPRPARPWR VAVIANVKGE TALPIQAPPD
60 70 80 90 100
AGAEFDRKET IEAIQSAIES DGHTTRFLSA DHTLLDSLRE YQPDICFNIA
110 120 130 140 150
EGIIGDAREA QVPALLEMLG IPYTASRVLA NALGLDKTMT KRIWRNLGIP
160 170 180 190 200
TASFQEFITG DEPLEADLSF PLFVKPAREG TGMGMDEGSI VYNENQLRRR
210 220 230 240 250
VKWVIEAYHQ PALVETYLPG REFTVGVLGR ADARRWSPKP HLYRADGFHR
260 270 280 290 300
FPILEVDNSN TVTPGVYGYA AKTLHPGEEG VPGFICPAQV EPDLAEKLWT
310 320 330 340 350
LAIRAHNAIG ALDVSRVDVR LDAHGNPRLL EINTLPGLTP GFSDLCVIAQ
360 370 380 390 400
AEGLSYRDLI LEILYLGASR WGLLEEAPQA IHVPLQAHHH TFQPAPMIFK
Length:400
Mass (Da):44,278
Last modified:April 5, 2011 - v1
Checksum:iFAF8BA7AD59EBA50
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012029 Genomic DNA. Translation: BAJ62641.1.
RefSeqiYP_004173241.1. NC_014960.1.

Genome annotation databases

EnsemblBacteriaiBAJ62641; BAJ62641; ANT_06070.
GeneIDi10172320.
KEGGiatm:ANT_06070.
PATRICi46852904. VBIAnaThe181647_0635.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012029 Genomic DNA. Translation: BAJ62641.1 .
RefSeqi YP_004173241.1. NC_014960.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAJ62641 ; BAJ62641 ; ANT_06070 .
GeneIDi 10172320.
KEGGi atm:ANT_06070.
PATRICi 46852904. VBIAnaThe181647_0635.

Phylogenomic databases

KOi K01921.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci ATHE926569:GH0F-618-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Whole genome sequence of Anaerolinea thermophila UNI-1."
    Narita-Yamada S., Kishi E., Watanabe Y., Takasaki K., Ankai A., Oguchi A., Fukui S., Takahashi M., Yashiro I., Hosoyama A., Sekiguchi Y., Hanada S., Fujita N.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1Imported.

Entry informationi

Entry nameiE8N1N6_ANATU
AccessioniPrimary (citable) accession number: E8N1N6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3