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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:ANT_23460Imported
OrganismiAnaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)Imported
Taxonomic identifieri926569 [NCBI]
Taxonomic lineageiBacteriaChloroflexiAnaerolineaeAnaerolinealesAnaerolineaceaeAnaerolinea
Proteomesi
  • UP000008922 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi926569.ANT_23460

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 205TubulinInterPro annotationAdd BLAST193
Domaini207 – 324Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

E8MYN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMNQPLSES FARIKVVGVG GGGCNAVNRM IEEGLQGIEF VAVNTDGQAL
60 70 80 90 100
MLSKADVRIR IGDKVTRGLG AGGNPEMGRK AAEESAEELY SALKGADMVF
110 120 130 140 150
VTAGMGGGTG TGAAPIIAQI AKEVGALTIG VVTRPFTFEG ARRAKSAEEG
160 170 180 190 200
IGNLKEHADT LIVIPNDRLL QMVDKRASLQ DAFRLADDVL RQGIQGISEL
210 220 230 240 250
ITVPGLINLD FADVRAIMSE GGAALMAVGH ASGEDRARIA AEMAISSQLL
260 270 280 290 300
DITIDGARGI LFNVTGGPDL TLFEVNQAAA IIKETAHPDV NLIFGAVIDP
310 320 330 340 350
KIGDEIRITV IATGFDRSGV RPAAERPMRV ENSQAPRPRP ASTPAPVQPA
360 370 380
PERPTPLQTP APTEHDFSRV VNTDDFDIPA FLRNRKR
Length:387
Mass (Da):40,914
Last modified:April 5, 2011 - v1
Checksum:i49437E5EB2EE3A41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012029 Genomic DNA Translation: BAJ64372.1

Genome annotation databases

EnsemblBacteriaiBAJ64372; BAJ64372; ANT_23460
KEGGiatm:ANT_23460

Similar proteinsi

Entry informationi

Entry nameiE8MYN6_ANATU
AccessioniPrimary (citable) accession number: E8MYN6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health