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Protein
Submitted name:

Glutaminyl Cyclase

Gene
N/A
Organism
Myxococcus xanthus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi40 – 401Calcium; via carbonyl oxygenCombined sources
Metal bindingi165 – 1651CalciumCombined sources
Metal bindingi166 – 1661Calcium; via carbonyl oxygenCombined sources
Metal bindingi167 – 1671CalciumCombined sources
Metal bindingi220 – 2201Calcium; via carbonyl oxygenCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sourcesImported, Metal-bindingCombined sourcesImported

Names & Taxonomyi

Protein namesi
Submitted name:
Glutaminyl CyclaseImported (EC:2.3.2.5Imported)
OrganismiMyxococcus xanthusImported
Taxonomic identifieri34 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeMyxococcus

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi122 ↔ 168Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3NOKX-ray1.65A/B1-248[»]
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiE7FH78.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108UIS. Bacteria.
COG3823. LUCA.

Family and domain databases

InterProiIPR007788. Glu_cyclase_2.
IPR011044. Quino_amine_DH_bsu.
[Graphical view]
PfamiPF05096. Glu_cyclase_2. 1 hit.
[Graphical view]
SUPFAMiSSF50969. SSF50969. 1 hit.

Sequencei

Sequence statusi: Complete.

E7FH78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPTNRPVPD AGGSVQEPVR RVAHIIREYP HATNAFTQGL VFHQGHFFES
60 70 80 90 100
TGHQGTLRQL SLESAQPVWM ERLGNIFAEG LASDGERLYQ LTWTEGLLFT
110 120 130 140 150
WSGMPPQRER TTRYSGEGWG LCYWNGKLVR SDGGTMLTFH EPDGFALVGA
160 170 180 190 200
VQVKLRGQPV ELINELECAN GVIYANIWHS SDVLEIDPAT GTVVGVIDAS
210 220 230 240
ALTRAVAGQV TNPEAVLNGI AVEPGSGRIF MTGKLWPRLF EVRLDVVD
Length:248
Mass (Da):27,213
Last modified:March 8, 2011 - v1
Checksum:iF4DFE3C20030DDF8
GO

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3NOKX-ray1.65A/B1-248[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4108UIS. Bacteria.
COG3823. LUCA.

Miscellaneous databases

EvolutionaryTraceiE7FH78.

Family and domain databases

InterProiIPR007788. Glu_cyclase_2.
IPR011044. Quino_amine_DH_bsu.
[Graphical view]
PfamiPF05096. Glu_cyclase_2. 1 hit.
[Graphical view]
SUPFAMiSSF50969. SSF50969. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus."
    Carrillo D.R., Parthier C., Janckel N., Grandke J., Stelter M., Schilling S., Boehme M., Neumann P., Wolf R., Demuth H.U., Stubbs M.T., Rahfeld J.U.
    Biol. Chem. 391:1419-1428(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) IN COMPLEX WITH CALCIUM, ACTIVE SITE.

Entry informationi

Entry nameiE7FH78_MYXXA
AccessioniPrimary (citable) accession number: E7FH78
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 16, 2016
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sourcesImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.